标题
Disialoganglioside GD2 as a therapeutic target for human diseases
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 19, Issue 3, Pages 349-362
出版商
Informa Healthcare
发表日期
2015-01-21
DOI
10.1517/14728222.2014.986459
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A new liquid chromatography/tandem mass spectrometry method for quantification of gangliosides in human plasma
- (2014) Qianyang Huang et al. ANALYTICAL BIOCHEMISTRY
- Etoposide-loaded immunoliposomes as active targeting agents for GD2-positive malignancies
- (2014) Brandon S Brown et al. CANCER BIOLOGY & THERAPY
- Gangliosides Drive the Tumor Infiltration and Function of Myeloid-Derived Suppressor Cells
- (2014) A. Wondimu et al. CANCER RESEARCH
- Phase I Trial of a Bivalent Gangliosides Vaccine in Combination with β-Glucan for High-Risk Neuroblastoma in Second or Later Remission
- (2014) Brian H. Kushner et al. CLINICAL CANCER RESEARCH
- Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy
- (2014) Ming Cheng et al. INTERNATIONAL JOURNAL OF CANCER
- Key role for myeloid cells: Phase II results of anti-GD2antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma
- (2014) Nai-Kong V. Cheung et al. INTERNATIONAL JOURNAL OF CANCER
- Phase I Trial of a Novel Anti-GD2 Monoclonal Antibody, Hu14.18K322A, Designed to Decrease Toxicity in Children With Refractory or Recurrent Neuroblastoma
- (2014) Fariba Navid et al. JOURNAL OF CLINICAL ONCOLOGY
- An aberrant spliced transcript of focal adhesion kinase is exclusively expressed in human breast cancer
- (2014) Ling Yao et al. Journal of Translational Medicine
- Preclinical Evaluation of Multistep Targeting of Diasialoganglioside GD2 Using an IgG-scFv Bispecific Antibody with High Affinity for GD2 and DOTA Metal Complex
- (2014) S. M. Cheal et al. MOLECULAR CANCER THERAPEUTICS
- Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia
- (2014) Mickaël Terme et al. PLoS One
- Endothelin A Receptor Antagonism Enhances Inhibitory Effects of Anti-Ganglioside GD2 Monoclonal Antibody on Invasiveness and Viability of Human Osteosarcoma Cells
- (2014) Bo Liu et al. PLoS One
- GD2-Targeted Immunotherapy and Radioimmunotherapy
- (2014) Konstantin Dobrenkov et al. SEMINARS IN ONCOLOGY
- Structure Based Refinement of a Humanized Monoclonal Antibody That Targets Tumor Antigen Disialoganglioside GD2
- (2014) Mahiuddin Ahmed et al. Frontiers in Immunology
- Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody
- (2014) Bryan D Choi et al. OncoImmunology
- Vaccination with anti-idiotype antibody ganglidiomab mediates a GD2-specific anti-neuroblastoma immune response
- (2013) Holger N. Lode et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy
- (2013) Mahiuddin Ahmed et al. FEBS LETTERS
- Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency
- (2013) Marie Vincent et al. INTERNATIONAL JOURNAL OF CANCER
- In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors
- (2013) Mahiuddin Ahmed et al. PLoS One
- Generation of Murine Sympathoadrenergic Progenitor-Like Cells from Embryonic Stem Cells and Postnatal Adrenal Glands
- (2013) Shobhit Saxena et al. PLoS One
- An MRI-Visible Non-Viral Vector Bearing GD2 Single Chain Antibody for Targeted Gene Delivery to Human Bone Marrow Mesenchymal Stem Cells
- (2013) Pengfei Pang et al. PLoS One
- Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells
- (2013) Y.-J. Liang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How Do Gangliosides Regulate RTKs Signaling?
- (2013) Sylvain Julien et al. Cells
- The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting
- (2012) S Kailayangiri et al. BRITISH JOURNAL OF CANCER
- Phase II trial of hu14.18-IL2 for patients with metastatic melanoma
- (2012) Mark R. Albertini et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3
- (2012) Hidenobu Shibuya et al. CANCER SCIENCE
- Disialyl gangliosides enhance tumor phenotypes with differential modalities
- (2012) Koichi Furukawa et al. GLYCOCONJUGATE JOURNAL
- Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment
- (2012) Nidale Tarek et al. JOURNAL OF CLINICAL INVESTIGATION
- Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
- (2012) Venkata Lokesh Battula et al. JOURNAL OF CLINICAL INVESTIGATION
- Murine Anti-GD2 Monoclonal Antibody 3F8 Combined With Granulocyte-Macrophage Colony-Stimulating Factor and 13-Cis-Retinoic Acid in High-Risk Patients With Stage 4 Neuroblastoma in First Remission
- (2012) Nai-Kong V. Cheung et al. JOURNAL OF CLINICAL ONCOLOGY
- Ganglioside Inhibition of CD8+ T Cell Cytotoxicity: Interference with Lytic Granule Trafficking and Exocytosis
- (2012) H. C. Lee et al. JOURNAL OF IMMUNOLOGY
- Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity
- (2012) Anastasia Shibina et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Essential Roles of Gangliosides in the Formation and Maintenance of Membrane Microdomains in Brain Tissues
- (2012) Yuhsuke Ohmi et al. NEUROCHEMICAL RESEARCH
- Anti-CD3 × anti-GD2 bispecific antibody redirects T-cell cytolytic activity to neuroblastoma targets
- (2012) Maxim Yankelevich et al. PEDIATRIC BLOOD & CANCER
- Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD2 Coated Nanoparticles
- (2012) Amanda Tivnan et al. PLoS One
- Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo
- (2012) Nai-Kong V. Cheung et al. OncoImmunology
- Expression of GD2 and GD3 Gangliosides in Human Embryonic Neural Stem Cells
- (2011) Makoto Yanagisawa et al. ASN Neuro
- Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
- (2011) C. U. Louis et al. BLOOD
- Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy
- (2011) Thorsten Simon et al. BMC CANCER
- Impact of minimal tumor burden on antibody response to vaccination
- (2011) Soo-Kie Kim et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Mesenchymal Stem Cells
- (2011) Adam R. Williams et al. CIRCULATION RESEARCH
- Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function
- (2011) Lixian Dong et al. GLYCOCONJUGATE JOURNAL
- NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
- (2011) Ruth Esser et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Successful Multifold Dose Escalation of Anti-GD2Monoclonal Antibody 3F8 in Patients With Neuroblastoma: A Phase I Study
- (2011) Brian H. Kushner et al. JOURNAL OF CLINICAL ONCOLOGY
- Activation of Peripheral-Blood Granulocytes Is Strongly Correlated With Patient Outcome After Immunotherapy With Anti-GD2 Monoclonal Antibody and Granulocyte-Macrophage Colony-Stimulating Factor
- (2011) Irene Y. Cheung et al. JOURNAL OF CLINICAL ONCOLOGY
- A Monoclonal Antibody to O-Acetyl-GD2 Ganglioside and Not to GD2 Shows Potent Anti-Tumor Activity without Peripheral Nervous System Cross-Reactivity
- (2011) Nidia Alvarez-Rueda et al. PLoS One
- Genotypes of NK Cell KIR Receptors, Their Ligands, and Fc Receptors in the Response of Neuroblastoma Patients to Hu14.18-IL2 Immunotherapy
- (2010) D. C. Delgado et al. CANCER RESEARCH
- GD2 expression is closely associated with neuronal differentiation of human umbilical cord blood-derived mesenchymal stem cells
- (2010) Hye Jin Jin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Small-Molecule Ligands of GD2 Ganglioside, Designed from NMR Studies, Exhibit Induced-Fit Binding and Bioactivity
- (2010) Wenyong Tong et al. CHEMISTRY & BIOLOGY
- Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity
- (2010) Alessandra Jales et al. IMMUNOLOGY
- Antitumor Activity of Hu14.18-IL2 in Patients With Relapsed/Refractory Neuroblastoma: A Children's Oncology Group (COG) Phase II Study
- (2010) Suzanne Shusterman et al. JOURNAL OF CLINICAL ONCOLOGY
- Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma
- (2010) Alice L. Yu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function
- (2010) Valeria Sordi et al. STEM CELLS
- Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method
- (2009) L Li et al. CANCER GENE THERAPY
- Neural Ganglioside GD2 Identifies a Subpopulation of Mesenchymal Stem Cells in Umbilical Cord
- (2009) Jie Xu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Immunogenicity of the Hu14.18-IL2 Immunocytokine Molecule in Adults With Melanoma and Children With Neuroblastoma
- (2009) J. A. Hank et al. CLINICAL CANCER RESEARCH
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- Systematic amino acid substitutions improved efficiency of GD2-peptide mimotope vaccination against neuroblastoma
- (2009) Matthias Bleeke et al. EUROPEAN JOURNAL OF CANCER
- Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study
- (2009) Katherine K. Matthay et al. JOURNAL OF CLINICAL ONCOLOGY
- Reducing Epitope Spread during Affinity Maturation of an Anti-Ganglioside GD2 Antibody
- (2009) J. Hu et al. JOURNAL OF IMMUNOLOGY
- Elevated Levels of Select Gangliosides in T Cells from Renal Cell Carcinoma Patients Is Associated with T Cell Dysfunction
- (2009) S. Biswas et al. JOURNAL OF IMMUNOLOGY
- Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma
- (2009) Kim Kramer et al. JOURNAL OF NEURO-ONCOLOGY
- High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial
- (2008) Andrew DJ Pearson et al. LANCET ONCOLOGY
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- (2008) Martin A Pule et al. NATURE MEDICINE
- The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis
- (2008) Long-Jun Dai et al. Stem Cell Research
- Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains
- (2007) Adriane Regina Todeschini et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Polysialic acid in the plasticity of the developing and adult vertebrate nervous system
- (2007) Urs Rutishauser NATURE REVIEWS NEUROSCIENCE
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