Lactoperoxidase as a potential drug target

Leonurus cardiaca L. herb extracts and their constituents promote lactoperoxidase activity

(2015) Jörg Flemmig et al.   Journal of Functional Foods

Mode of binding of the antithyroid drug propylthiouracil to mammalian haem peroxidases

(2015) R. P. Singh et al.   Acta Crystallographica Section F-Structural Biology Communications

Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase

(2014) Jörg Flemmig et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates

(2013) Louisa V. Forbes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

(−)-Epicatechin regenerates the chlorinating activity of myeloperoxidase in vitro and in neutrophil granulocytes

(2013) Jörg Flemmig et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Evaluation of New Scaffolds of Myeloperoxidase Inhibitors by Rational Design Combined with High-Throughput Virtual Screening

(2012) Iyas Aldib et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhancement of Respiratory Mucosal Antiviral Defenses by the Oxidation of Iodide

(2011) Anthony J. Fischer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

(2011) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

Hypothiocyanous Acid: Benign or Deadly?

(2011) Tessa J. Barrett et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effects of Mono- and Disaccharides on the Antimicrobial Activity of Bovine Lactoperoxidase System

(2011) AHMAD NIMATULLAH AL-BAARRI et al.   JOURNAL OF FOOD PROTECTION

Human myeloperoxidase in innate and acquired immunity

(2010) Juergen Arnhold et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases

(2010) Amit K. Singh et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Interactions of melatonin and serotonin with lactoperoxidase enzyme

(2010) Melda Şişecioğlu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

(2009) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

Inhibition of Lactoperoxidase by Its Own Catalytic Product: Crystal Structure of the Hypothiocyanate-Inhibited Bovine Lactoperoxidase at 2.3-Å Resolution

(2009) A.K. Singh et al.   BIOPHYSICAL JOURNAL

Peroxidative Metabolism of β2-Agonists Salbutamol and Fenoterol and Their Analogues

(2009) Krzysztof J. Reszka et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Kinetics and Mechanisms of the Reaction of Hypothiocyanous Acid with 5-Thio-2-nitrobenzoic Acid and Reduced Glutathione

(2009) Péter Nagy et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The role of hypothiocyanous acid (HOSCN) in biological systems

(2009) Clare L. Hawkins   FREE RADICAL RESEARCH

Binding Modes of Aromatic Ligands to Mammalian Heme Peroxidases with Associated Functional Implications

(2009) Amit K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Evidence of Substrate Specificity in Mammalian Peroxidases

(2009) Ishfaq Ahmed Sheikh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mode of Binding of the Tuberculosis Prodrug Isoniazid to Heme Peroxidases

(2009) Amit K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role of Proximal Histidine-Asparagine Interaction in Mammalian Peroxidases

(2009) Xavier Carpena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases

(2009) Y. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications

(2008) Michael J. Davies et al.   ANTIOXIDANTS & REDOX SIGNALING

Intramolecular Electron Transfer versus Substrate Oxidation in Lactoperoxidase: Investigation of Radical Intermediates by Stopped-Flow Absorption Spectrophotometry and (9−285 GHz) Electron Paramagnetic Resonance Spectroscopy†

(2008) Alistair J. Fielding et al.   BIOCHEMISTRY

Non-Vital Polymorphonuclear Leukocytes Express Myeloperoxidase on their Surface

(2008) Jörg Flemmig et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Thiocyanate concentration in saliva of cystic fibrosis patients.

(2008) Łukasz Minarowski et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Inhibition of Lactoperoxidase-Catalyzed 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and Tyrosine Oxidation by Tyrosine-Containing Random Amino Acid Copolymers

(2008) Morten R. Clausen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Crystal Structure of Lactoperoxidase at 2.4 Å Resolution

(2008) Amit Kumar Singh et al.   JOURNAL OF MOLECULAR BIOLOGY