Effects of metformin on clinical outcome in diabetic patients with advanced HCC receiving sorafenib

Does cancer risk increase with HbA1c, independent of diabetes?

(2014) J C de Beer et al.   BRITISH JOURNAL OF CANCER

Paradoxic effects of metformin on endothelial cells and angiogenesis

(2014) Katiuscia Dallaglio et al.   CARCINOGENESIS

Hyperglycemia and chronic liver diseases on risk of hepatocellular carcinoma in Chinese patients with type 2 diabetes--National cohort of Taiwan Diabetes Study

(2014) Chia-Ing Li et al.   INTERNATIONAL JOURNAL OF CANCER

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

(2014) Floris H. Groenendijk et al.   INTERNATIONAL JOURNAL OF CANCER

Anti-Diabetic Medications and the Risk of Hepatocellular Cancer: A Systematic Review and Meta-Analysis

(2013) Siddharth Singh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The LKB1-AMPK Pathway—Friend or Foe in Cancer?

(2013) D. Grahame Hardie   CANCER CELL

Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model

(2012) A. Cittadini et al.   DIABETES

Enhancers and attenuators of risk associations of chronic hepatitis B virus infection with hepatocellular carcinoma in type 2 diabetes

(2012) Xilin Yang et al.   ENDOCRINE-RELATED CANCER

Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies

(2012) Hsiao-Ping Chen et al.   GUT

Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial

(2012) Jordi Bruix et al.   JOURNAL OF HEPATOLOGY

Metformin pathways

(2012) Li Gong et al.   Pharmacogenetics and Genomics

HbA1c Measured in Stored Erythrocytes Is Positively Linearly Associated with Mortality in Individuals with Diabetes Mellitus

(2012) Diewertje Sluik et al.   PLoS One

Metformin Accelerates the Growth of BRAF V600E -Driven Melanoma by Upregulating VEGF-A

(2012) Matthew J. Martin et al.   Cancer Discovery

Metformin restores endothelial function in aorta of diabetic rats

(2011) Cristina M Sena et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metformin associated with lower mortality in diabetic patients with early stage hepatocellular carcinoma after radiofrequency ablation

(2011) Tsung-Ming Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

(2011) T Tomic et al.   Cell Death & Disease

Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis

(2010) R. M. Memmott et al.   Cancer Prevention Research

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Associations of Hyperglycemia and Insulin Usage With the Risk of Cancer in Type 2 Diabetes: The Hong Kong Diabetes Registry

(2010) X. Yang et al.   DIABETES

Regulation of hepatic metabolism by AMPK

(2010) Marc Foretz et al.   JOURNAL OF HEPATOLOGY

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease

(2010) Valter Donadon et al.   LIVER INTERNATIONAL

Glycated hemoglobin and antidiabetic strategies as risk factors for hepatocellular carcinoma

(2010) Valter Donadon   WORLD JOURNAL OF GASTROENTEROLOGY

Metformin decreases angiogenesis via NF-κB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1

(2009) Bee K. Tan et al.   CARDIOVASCULAR RESEARCH

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE