Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation
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Title
Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF CANCER
Volume 136, Issue 6, Pages 1434-1444
Publisher
Wiley
Online
2014-08-01
DOI
10.1002/ijc.29113
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Note: Only part of the references are listed.- Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
- (2014) Kıvanç Birsoy et al. NATURE
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- (2013) Claudia Fumarola et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2013) David B. Shackelford et al. CANCER CELL
- The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models
- (2013) Y. Pignochino et al. CLINICAL CANCER RESEARCH
- The effect of metformin and thiazolidinedione use on lung cancer in diabetics
- (2012) Peter J Mazzone et al. BMC CANCER
- A Phase II Study of Sorafenib in Patients with Platinum-Pretreated, Advanced (Stage IIIb or IV) Non-Small Cell Lung Cancer with a KRAS Mutation
- (2012) A.-M. C. Dingemans et al. CLINICAL CANCER RESEARCH
- Metformin Inhibits Growth of Thyroid Carcinoma Cells, Suppresses Self-Renewal of Derived Cancer Stem Cells, and Potentiates the Effect of Chemotherapeutic Agents
- (2012) Guofang Chen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Metformin in cancer: translational challenges
- (2012) Ryan J O Dowling et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Differential inhibitory effects of two Raf-targeting drugs, sorafenib and PLX4720, on the growth of multidrug-resistant cells
- (2012) Ki-Hwan Eum et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo
- (2012) R. Coriat et al. MOLECULAR CANCER THERAPEUTICS
- Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival
- (2012) Xiaoyun Liao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects
- (2012) M A Pierotti et al. ONCOGENE
- The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
- (2012) S. A. Hawley et al. SCIENCE
- Metformin Accelerates the Growth of BRAF V600E -Driven Melanoma by Upregulating VEGF-A
- (2012) Matthew J. Martin et al. Cancer Discovery
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
- (2011) G. Z. Rocha et al. CLINICAL CANCER RESEARCH
- Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels
- (2011) P. T. Mungai et al. MOLECULAR AND CELLULAR BIOLOGY
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- Frequent homozygous deletion of the LKB1/STK11 gene in non-small cell lung cancer
- (2011) R K Gill et al. ONCOGENE
- Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant hep G2 cells through a mitochondria-dependent oxidative stress mechanism
- (2010) Jeng-Fong Chiou et al. CANCER BIOLOGY & THERAPY
- Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?
- (2010) I. Ben Sahra et al. MOLECULAR CANCER THERAPEUTICS
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
- (2010) A. Alexander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer
- (2009) Sao Jiralerspong et al. JOURNAL OF CLINICAL ONCOLOGY
- Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
- (2008) Xu Huang et al. BIOCHEMICAL JOURNAL
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
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