Syntheses and Immunological Evaluation of Self-Adjuvanting Clustered N -Acetyl and N -Propionyl Sialyl-Tn Combined with a T-helper Cell Epitope as Antitumor Vaccine Candidates

A Synthetic Glycopeptide Vaccine for the Induction of a Monoclonal Antibody that Differentiates between Normal and Tumor Mammary Cells and Enables the Diagnosis of Human Pancreatic Cancer

(2016) Björn Palitzsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide

(2015) Pamela Thompson et al.   CHEMICAL COMMUNICATIONS

Synthetic self-adjuvanting glycopeptide cancer vaccines

(2015) David M. McDonald et al.   Frontiers in Chemistry

Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells

(2014) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Fully Synthetic Four-Component Antitumor Vaccine Consisting of a Mucin Glycopeptide Antigen Combined with Three Different T-Helper-Cell Epitopes

(2014) Björn Palitzsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Glycosylation Using In(OTf)3 as a Lewis Acid: Activation of N-Phenyltrifluoroacetimidate or Thioglycosides with Halogenated Reagents or PhIO

(2014) Regina M. Salmasan et al.   CHEMISTRY LETTERS

Self-Adjuvanting Synthetic Antitumor Vaccines from MUC1 Glycopeptides Conjugated to T-Cell Epitopes from Tetanus Toxoid

(2013) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The development of synthetic antitumour vaccines from mucin glycopeptide antigens

(2013) Nikola Gaidzik et al.   CHEMICAL SOCIETY REVIEWS

A Vision for Vaccines Built from Fully Synthetic Tumor-Associated Antigens: From the Laboratory to the Clinic

(2013) Rebecca M. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Survival Advantage in Patients with Metastatic Breast Cancer Receiving Endocrine Therapy plus Sialyl Tn-KLH Vaccine: Post Hoc Analysis of a Large Randomized Trial

(2013) Nuhad K. Ibrahim et al.   Journal of Cancer

Fully Synthetic Self-Adjuvanting Thioether-Conjugated GlycopeptideLipopeptide Antitumor Vaccines for the Induction of Complement-Dependent Cytotoxicity against Tumor Cells

(2012) Hui Cai et al.   CHEMISTRY-A EUROPEAN JOURNAL

a Totally Synthetic, Self-Assembling, Adjuvant-Free MUC1 Glycopeptide Vaccine for Cancer Therapy

(2012) Zhi-Hua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam3CysSer

(2011) Brendan L. Wilkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Antitumor Vaccines Containing MUC1 Glycopeptides with Two Immunodominant Domains-Induction of a Strong Immune Response against Breast Tumor Tissues

(2011) Nikola Gaidzik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells

(2011) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Phase III Multicenter Clinical Trial of the Sialyl-TN (STn)-Keyhole Limpet Hemocyanin (KLH) Vaccine for Metastatic Breast Cancer

(2011) D. Miles et al.   ONCOLOGIST

Enhancement of the Immunogenicity of Synthetic Carbohydrate Vaccines by Chemical Modifications of STn Antigen

(2010) Fan Yang et al.   ACS Chemical Biology

Fully Synthetic Vaccines Consisting of Tumor-Associated MUC1 Glycopeptides and a Lipopeptide Ligand of the Toll-like Receptor 2

(2010) Anton Kaiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2

(2010) Ryoko Sawahata et al.   MICROBES AND INFECTION

Synthesis of N-modified sTn analogs and evaluation of their immunogenicities by microarray-based immunoassay

(2010) Sk Sahabuddin et al.   TETRAHEDRON

A Synthetic Vaccine Consisting of a Tumor-Associated Sialyl-TN-MUC1 Tandem-Repeat Glycopeptide and Tetanus Toxoid: Induction of a Strong and Highly Selective Immune Response

(2009) Anton Kaiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent development in carbohydrate-based cancer vaccines

(2009) Zhongwu Guo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY