Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA

Reversible modification of DNA by methyltransferase-catalyzed transfer and light-triggered removal of photo-caging groups

(2018) Lea Anhäuser et al.   CHEMICAL COMMUNICATIONS

Interactions, localization, and phosphorylation of the m 6 A generating METTL3–METTL14–WTAP complex

(2018) Eva Schöller et al.   RNA

N6-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay

(2017) Xiao Shu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

m6A modulates haematopoietic stem and progenitor cell specification

(2017) Chunxia Zhang et al.   NATURE

A benzylic linker promotes methyltransferase catalyzed norbornene transfer for rapid bioorthogonal tetrazine ligation

(2017) F. Muttach et al.   Chemical Science

Modifying the 5′-Cap for Click Reactions of Eukaryotic mRNA and To Tune Translation Efficiency in Living Cells

(2016) Josephin M. Holstein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-pot modification of 5′-capped RNA based on methionine analogs

(2016) Fabian Muttach et al.   METHODS

Dual randomization of oligonucleotides to reduce the bias in ribosome-profiling libraries

(2016) Aarón Lecanda et al.   METHODS

Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing

(2016) Wen Xiao et al.   MOLECULAR CELL

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

(2016) Irmgard U. Haussmann et al.   NATURE

m6A modulates neuronal functions and sex determination in Drosophila

(2016) Tina Lence et al.   NATURE

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

A Biocatalytic Cascade for Versatile One-Pot Modification of mRNA Starting from Methionine Analogues

(2015) Fabian Muttach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

(2015) Bastian Linder et al.   NATURE METHODS

Engineering Giardia lamblia trimethylguanosine synthase (GlaTgs2) to transfer non-natural modifications to the RNA 5'-cap

(2015) Josephin Marie Holstein et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Enzymatic modification of 5′-capped RNA with a 4-vinylbenzyl group provides a platform for photoclick and inverse electron-demand Diels–Alder reaction

(2015) Josephin Marie Holstein et al.   Chemical Science

Facile Chemoenzymatic Strategies for the Synthesis and Utilization ofS-Adenosyl-L-Methionine Analogues

(2014) Shanteri Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-ResolutionN6-Methyladenosine (m6A) Map Using Photo-Crosslinking-Assisted m6A Sequencing

(2014) Kai Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal site-specific labeling of the 5′-cap structure in eukaryotic mRNAs

(2014) Josephin Marie Holstein et al.   CHEMICAL COMMUNICATIONS

A Chemo-Enzymatic Approach for Site-Specific Modification of the RNA Cap

(2013) Daniela Schulz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

(2013) Jean-Michel Fustin et al.   CELL

Identification of a Selective Polymerase Enables Detection of N6-Methyladenosine in RNA

(2013) Emily M. Harcourt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA

(2013) N. Liu et al.   RNA

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

A Selenium-Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild-Type Protein Methyltransferases

(2012) Sophie Willnow et al.   CHEMBIOCHEM

Bioorthogonal Profiling of Protein Methylation Using Azido Derivative of S-Adenosyl-l-methionine

(2012) Kabirul Islam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells

(2012) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases

(2012) Miglė Tomkuvienė et al.   NUCLEIC ACIDS RESEARCH

Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

(2011) Kabirul Islam et al.   ACS Chemical Biology

Labeling Substrates of Protein Arginine Methyltransferase with Engineered Enzymes and MatchedS-Adenosyl-l-methionine Analogues

(2011) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling

(2010) Y. Motorin et al.   NUCLEIC ACIDS RESEARCH