A Biocatalytic Cascade for Versatile One-Pot Modification of mRNA Starting from Methionine Analogues

Widespread occurrence ofN6-methyladenosine in bacterial mRNA

(2015) Xin Deng et al.   NUCLEIC ACIDS RESEARCH

Engineering Giardia lamblia trimethylguanosine synthase (GlaTgs2) to transfer non-natural modifications to the RNA 5'-cap

(2015) Josephin Marie Holstein et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Enzymatic modification of 5′-capped RNA with a 4-vinylbenzyl group provides a platform for photoclick and inverse electron-demand Diels–Alder reaction

(2015) Josephin Marie Holstein et al.   Chemical Science

Quantum Chemical Calculations and Experimental Validation of the Photoclick Reaction for Fluorescent Labeling of the 5’ cap of Eukaryotic mRNAs

(2015) Daniela Stummer et al.   ChemistryOpen

A sensitive mass spectrum assay to characterize engineered methionine adenosyltransferases with S-alkyl methionine analogues as substrates

(2014) Rui Wang et al.   ANALYTICAL BIOCHEMISTRY

Facile Chemoenzymatic Strategies for the Synthesis and Utilization ofS-Adenosyl-L-Methionine Analogues

(2014) Shanteri Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal site-specific labeling of the 5′-cap structure in eukaryotic mRNAs

(2014) Josephin Marie Holstein et al.   CHEMICAL COMMUNICATIONS

Non-histone protein methylation as a regulator of cellular signalling and function

(2014) Kyle K. Biggar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Large-Scale, Protection-Free Synthesis of Se-Adenosyl-l-selenomethionine Analogues and Their Application as Cofactor Surrogates of Methyltransferases

(2014) Ian R. Bothwell et al.   ORGANIC LETTERS

Enhanced Chemical Stability of AdoMet Analogues for Improved Methyltransferase-Directed Labeling of DNA

(2013) Gražvydas Lukinavičius et al.   ACS Chemical Biology

A Chemo-Enzymatic Approach for Site-Specific Modification of the RNA Cap

(2013) Daniela Schulz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alternative substrates selective for S-adenosylmethionine synthetases from pathogenic bacteria

(2013) Stephen P. Zano et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Phospholipid methylation in mammals: from biochemistry to physiological function

(2013) Dennis E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Alkylating enzymes

(2013) Ludger A Wessjohann et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Progress in the research of S-adenosyl-l-methionine production

(2012) Ju Chu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Methylation – an uncommon modification of glycans

(2012) Erika Staudacher   BIOLOGICAL CHEMISTRY

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

A Selenium-Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild-Type Protein Methyltransferases

(2012) Sophie Willnow et al.   CHEMBIOCHEM

Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells

(2012) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases

(2012) Miglė Tomkuvienė et al.   NUCLEIC ACIDS RESEARCH

An enzyme-coupled high-throughput assay for screening RNA methyltransferase activity inE. Colicell lysate

(2012) Daniela Schulz et al.   RNA Biology

Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

(2011) Kabirul Islam et al.   ACS Chemical Biology

Labeling Substrates of Protein Arginine Methyltransferase with Engineered Enzymes and MatchedS-Adenosyl-l-methionine Analogues

(2011) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling

(2010) Y. Motorin et al.   NUCLEIC ACIDS RESEARCH

Structure-function relationships in methionine adenosyltransferases

(2008) G. D. Markham et al.   CELLULAR AND MOLECULAR LIFE SCIENCES