Applications of nanoparticles in cancer medicine and beyond: optical and multimodalin vivoimaging, tissue targeting and drug delivery

Imaging agents based on lanthanide doped nanoparticles

(2015) L. Prodi et al.   CHEMICAL SOCIETY REVIEWS

Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors

(2015) K. David Wegner et al.   CHEMICAL SOCIETY REVIEWS

Reinvention of chemotherapy

(2015) Tu Nguyen-Ngoc et al.   CURRENT OPINION IN ONCOLOGY

Critical Review on the Toxicity of Some Widely Used Engineered Nanoparticles

(2015) Varsha Srivastava et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Liposomes as nanomedical devices

(2015) Giuseppina Bozzuto et al.   International Journal of Nanomedicine

Advanced targeted nanomedicine

(2015) Mohan C.M. Arachchige et al.   JOURNAL OF BIOTECHNOLOGY

Quantum dot-based lab-on-a-bead system for multiplexed detection of free and total prostate-specific antigens in clinical human serum samples

(2015) Kristina Brazhnik et al.   Nanomedicine-Nanotechnology Biology and Medicine

Application of functional quantum dot nanoparticles as fluorescence probes in cell labeling and tumor diagnostic imaging

(2015) Mei-Xia Zhao et al.   Nanoscale Research Letters

Upconversion Fluorescence-SERS Dual-Mode Tags for Cellular and in Vivo Imaging

(2014) Xiaojuan Niu et al.   ACS Applied Materials & Interfaces

Tumor-Homing Glycol Chitosan-Based Optical/PET Dual Imaging Nanoprobe for Cancer Diagnosis

(2014) Sangmin Lee et al.   BIOCONJUGATE CHEMISTRY

Multimodal imaging for improved diagnosis and treatment of cancers

(2014) Clare M. C. Tempany et al.   CANCER

Dye-doped silica nanoparticles as luminescent organized systems for nanomedicine

(2014) M. Montalti et al.   CHEMICAL SOCIETY REVIEWS

Polymer-encapsulated organic nanoparticles for fluorescence and photoacoustic imaging

(2014) Kai Li et al.   CHEMICAL SOCIETY REVIEWS

Nanomedicine Based Nanoparticles for Neurological Disorders

(2014) Bhasker Sriramoju et al.   CURRENT MEDICINAL CHEMISTRY

Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges

(2014) Sophie Laurent et al.   Expert Opinion on Drug Delivery

Theranostic nanoparticles for future personalized medicine

(2014) Ju Hee Ryu et al.   JOURNAL OF CONTROLLED RELEASE

State-of-the-art in design rules for drug delivery platforms: Lessons learned from FDA-approved nanomedicines

(2014) Charlene M. Dawidczyk et al.   JOURNAL OF CONTROLLED RELEASE

Direct Probes of 4 nm Diameter Gold Nanoparticles Interacting with Supported Lipid Bilayers

(2014) Julianne M. Troiano et al.   Journal of Physical Chemistry C

Multimodal Polymer Nanoparticles with Combined 19F Magnetic Resonance and Optical Detection for Tunable, Targeted, Multimodal Imaging in Vivo

(2014) Barbara E. Rolfe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual-Modal Magnetic Resonance and Fluorescence Imaging of Atherosclerotic Plaques in Vivo Using VCAM-1 Targeted Tobacco Mosaic Virus

(2014) Michael A. Bruckman et al.   NANO LETTERS

Managing diabetes with nanomedicine: challenges and opportunities

(2014) Omid Veiseh et al.   NATURE REVIEWS DRUG DISCOVERY

Essentials in intraoperative indocyanine green videoangiography assessment for intracranial aneurysm surgery: conclusions from 295 consecutively clipped aneurysms and review of the literature

(2014) Karl Roessler et al.   Neurosurgical Focus

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

(2014) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging

(2014) Stefania Biffi et al.   RSC Advances

Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy

(2014) Pengfei Rong et al.   Theranostics

Image-guided Pro-angiogenic Therapy in Diabetic Stroke Mouse Models Using a Multi-modal Nanoprobe

(2014) Ying-Ying Bai et al.   Theranostics

Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

(2014) Chongwei Chi et al.   Theranostics

Intracellular Delivery of Peptide Nucleic Acid and Organic Molecules Using Zeolite-L Nanocrystals

(2014) Alessandro Bertucci et al.   Advanced Healthcare Materials

Graphene Oxide Wrapped SERS Tags: Multifunctional Platforms toward Optical Labeling, Photothermal Ablation of Bacteria, and the Monitoring of Killing Effect

(2013) Donghai Lin et al.   ACS Applied Materials & Interfaces

Surface Chemistry Architecture of Silica Nanoparticles Determine the Efficiency of in Vivo Fluorescence Lymph Node Mapping

(2013) Marion Helle et al.   ACS Nano

Inherently Multimodal Nanoparticle-Driven Tracking and Real-Time Delineation of Orthotopic Prostate Tumors and Micrometastases

(2013) Tracy W. Liu et al.   ACS Nano

Core–Shell Lanthanide Upconversion Nanophosphors as Four-Modal Probes for Tumor Angiogenesis Imaging

(2013) Yun Sun et al.   ACS Nano

Prevention of Self-Quenching in Fluorescent Silica Nanoparticles by Efficient Energy Transfer

(2013) Damiano Genovese et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Background and Clinical Applications of Indocyanine Green Fluorescence Imaging of Hepatocellular Carcinoma

(2013) Takeaki Ishizawa et al.   ANNALS OF SURGICAL ONCOLOGY

Comparison of the Indocyanine Green Fluorescence and Blue Dye Methods in Detection of Sentinel Lymph Nodes in Early-stage Breast Cancer

(2013) Tomoharu Sugie et al.   ANNALS OF SURGICAL ONCOLOGY

Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes

(2013) Dongmei Yang et al.   BIOMATERIALS

Recent progress in the development of near-infrared fluorescent probes for bioimaging applications

(2013) Zhiqian Guo et al.   CHEMICAL SOCIETY REVIEWS

Nanoparticles Engineered with Rituximab and Loaded with Nutlin-3 Show Promising Therapeutic Activity in B-Leukemic Xenografts

(2013) R. Voltan et al.   CLINICAL CANCER RESEARCH

Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53wildtype JVM-2 But Not Towards p53mutated BJAB Leukemic Cells

(2013) R. Voltan et al.   CURRENT MEDICINAL CHEMISTRY

Image-guided drug delivery to the brain using nanotechnology

(2013) Hong Ding et al.   DRUG DISCOVERY TODAY

How nanotechnology can enhance docetaxel therapy

(2013) Na Zhang et al.   International Journal of Nanomedicine

Concepts and practices used to develop functional PLGA-based nanoparticulate systems

(2013) Hongkee Sah et al.   International Journal of Nanomedicine

Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis

(2013) Enrico Rampazzo et al.   Nanoscale

Image-guided cancer surgery using near-infrared fluorescence

(2013) Alexander L. Vahrmeijer et al.   Nature Reviews Clinical Oncology

New Potential Therapeutic Approach for the Treatment of B-Cell Malignancies Using Chlorambucil/Hydroxychloroquine-Loaded Anti-CD20 Nanoparticles

(2013) Nelly Mezzaroba et al.   PLoS One

A Raman-based endoscopic strategy for multiplexed molecular imaging

(2013) C. L. Zavaleta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superparamagnetic Iron Oxide Nanoparticles in Biomedicine: Applications and Developments in Diagnostics and Therapy

(2013) H. Ittrich et al.   ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN

Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites

(2013) Nikolai Khlebtsov et al.   Theranostics

Preclinical Assessment of a Zwitterionic Tantalum Oxide Nanoparticle X-ray Contrast Agent

(2012) Peter J. Bonitatibus et al.   ACS Nano

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles

(2012) Kai Yang et al.   ADVANCED MATERIALS

Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery

(2012) Fangqiong Tang et al.   ADVANCED MATERIALS

Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes

(2012) Xinglu Huang et al.   BIOMATERIALS

Gold Nanoparticles in Chemical and Biological Sensing

(2012) Krishnendu Saha et al.   CHEMICAL REVIEWS

SERS Tags: Novel Optical Nanoprobes for Bioanalysis

(2012) Yunqing Wang et al.   CHEMICAL REVIEWS

Silica-based nanoprobes for biomedical imaging and theranostic applications

(2012) Juan L. Vivero-Escoto et al.   CHEMICAL SOCIETY REVIEWS

Gold nanoparticles in theranostic oncology: current state-of-the-art

(2012) Sohail Akhter et al.   Expert Opinion on Drug Delivery

Cardiac quadruple-fusion imaging: A brief report on a novel integrated multimodality approach for in vivo visualization of transplanted stem cells

(2012) Michael Fiechter et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Macromolecular therapeutics in cancer treatment: The EPR effect and beyond

(2012) Hiroshi Maeda   JOURNAL OF CONTROLLED RELEASE

Fluorescent Nanoprobes Dedicated to in Vivo Imaging: From Preclinical Validations to Clinical Translation

(2012) Juliette Mérian et al.   MOLECULES

Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics

(2012) Anne Hellebust et al.   Nanomedicine

Near-infrared fluorescence sentinel lymph node mapping of the oral cavity in head and neck cancer patients

(2012) Joost R. van der Vorst et al.   ORAL ONCOLOGY

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Engineering of near IR fluorescent albumin nanoparticles for in vivo detection of colon cancer

(2012) Sarit Cohen et al.   JOURNAL OF NANOBIOTECHNOLOGY

Two-Order Targeted Brain Tumor Imaging by Using an Optical/Paramagnetic Nanoprobe across the Blood Brain Barrier

(2011) Huihui Yan et al.   ACS Nano

Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications

(2011) E.M. Sevick-Muraca   Annual Review of Medicine

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Finding the anaplastic focus in diffuse gliomas: The value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

(2011) Christian Ewelt et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Cancer Targeted Metallic Nanoparticle: Targeting Overview, Recent Advancement and Toxicity Concern

(2011) Sohail Akhter et al.   CURRENT PHARMACEUTICAL DESIGN

Quantum dots in cancer therapy

(2011) Guopei Luo et al.   Expert Opinion on Drug Delivery

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery

(2011) Boudewijn E. Schaafsma et al.   JOURNAL OF SURGICAL ONCOLOGY

Quantum dots, lighting up the research and development of nanomedicine

(2011) Yunqing Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

(2011) Suphiya Parveen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Multicolor core/shell silicananoparticles for in vivo and ex vivo imaging

(2011) Enrico Rampazzo et al.   Nanoscale

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier

(2011) Hirenkumar K. Makadia et al.   Polymers

PET/NIRF/MRI triple functional iron oxide nanoparticles

(2010) Jin Xie et al.   BIOMATERIALS

Metallic nanoparticles: technology overview & drug delivery applications in oncology

(2010) Mohammad Zaki Ahmad et al.   Expert Opinion on Drug Delivery

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

Energy Transfer from Silica Core−Surfactant Shell Nanoparticles to Hosted Molecular Fluorophores†

(2010) Enrico Rampazzo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

(Non-targeted) radioactive/fluorescent nanoparticles and their potential in combined pre- and intraoperative imaging during sentinel lymph node resection

(2010) Tessa Buckle et al.   NANOTECHNOLOGY

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Hybrid PET-optical imaging using targeted probes

(2010) Matthias Nahrendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy

(2008) Jaeyun Kim et al.   CHEMICAL SOCIETY REVIEWS

Quantum dots versus organic dyes as fluorescent labels

(2008) Ute Resch-Genger et al.   NATURE METHODS

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA