Human muscle-specific A-kinase anchoring protein polymorphisms modulate the susceptibility to cardiovascular diseases by altering cAMP/PKA signaling

Force development and intracellular Ca 2+ in intact cardiac muscles from gravin mutant mice

(2017) Zhitao Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Objective assessment of the evolutionary action equation for the fitness effect of missense mutations across CAGI-blinded contests

(2017) Panagiotis Katsonis et al.   HUMAN MUTATION

Activation of adrenergic receptor β2 promotes tumor progression and epithelial mesenchymal transition in tongue squamous cell carcinoma

(2017) Haichao Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

(2017) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Common and rare genetic variants and risk of CHD

(2017) Daniel I. Swerdlow et al.   Nature Reviews Cardiology

β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes

(2017) Misun Park et al.   Scientific Reports

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Left ventricular hypertrophy and cardiovascular disease risk prediction and reclassification in blacks and whites: The Atherosclerosis Risk in Communities Study

(2015) Tochi M. Okwuosa et al.   AMERICAN HEART JOURNAL

mAKAP—A Master Scaffold for Cardiac Remodeling

(2015) Catherine L. Passariello et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

(2015) Momoko Horikoshi et al.   PLoS Genetics

The Scaffold Protein Muscle A-Kinase Anchoring Protein β Orchestrates Cardiac Myocyte Hypertrophic Signaling Required for the Development of Heart Failure

(2014) Michael D. Kritzer et al.   Circulation-Heart Failure

A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness

(2014) Panagiotis Katsonis et al.   GENOME RESEARCH

Compartmentalization Role of A-Kinase Anchoring Proteins (AKAPs) in Mediating Protein Kinase A (PKA) Signaling and Cardiomyocyte Hypertrophy

(2014) Abeer Rababa'h et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

β1-Adrenergic Receptor Signaling Activates the Epithelial Calcium Channel, Transient Receptor Potential Vanilloid Type 5 (TRPV5), via the Protein Kinase A Pathway

(2014) Eline A. E. van der Hagen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anchored protein kinase A signalling in cardiac cellular electrophysiology

(2014) Siddarth Soni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Protein Kinase A and Phosphodiesterase-4D3 Binding to Coding Polymorphisms of Cardiac Muscle Anchoring Protein (mAKAP)

(2013) Abeer Rababa'h et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetics of Human Cardiovascular Disease

(2012) Sekar Kathiresan et al.   CELL

Transient exposure to hydrogen peroxide inhibits the ubiquitination of phosphorylated IκBα in TNFα-stimulated HEK293 cells

(2012) Yeji Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes

(2012) A H Ramirez et al.   PHARMACOGENOMICS JOURNAL

Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system

(2011) Alessandra Stangherlin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Association of Adiponectin With Left Ventricular Mass in Blacks

(2011) Aurelian Bidulescu et al.   Circulation-Heart Failure

Coordinating electrical activity of the heart: ankyrin polypeptides in human cardiac disease

(2011) Jerry Curran et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

AKAPs: The architectural underpinnings of local cAMP signaling

(2011) Michael D. Kritzer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genomics of Cardiovascular Disease

(2011) Christopher J. O'Donnell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cyclic AMP Control Measured in Two Compartments in HEK293 Cells: Phosphodiesterase KM Is More Important than Phosphodiesterase Localization

(2011) Karina Matthiesen et al.   PLoS One

cAMP-stimulated Protein Phosphatase 2A Activity Associated with Muscle A Kinase-anchoring Protein (mAKAP) Signaling Complexes Inhibits the Phosphorylation and Activity of the cAMP-specific Phosphodiesterase PDE4D3

(2010) Kimberly L. Dodge-Kafka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Networking with AKAPs: Context-dependent Regulation of Anchored Enzymes

(2010) E. J. Welch et al.   MOLECULAR INTERVENTIONS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

(2009) Lauren Monovich et al.   FEBS LETTERS

AKAP-Scaffolding Proteins and Regulation of Cardiac Physiology

(2009) J. R. H. Mauban et al.   PHYSIOLOGY

Distinct conformational changes in  -arrestin report biased agonism at seven-transmembrane receptors

(2008) A. K. Shukla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA