Elastin, arterial mechanics, and cardiovascular disease

Matrix ageing and vascular impacts: focus on elastin fragmentation

(2016) Laurent Duca et al.   CARDIOVASCULAR RESEARCH

Metalloproteinase production from macrophages - a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction

(2016) Andrew C. Newby   EXPERIMENTAL PHYSIOLOGY

Integrin β3 inhibition is a therapeutic strategy for supravalvular aortic stenosis

(2016) Ashish Misra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization

(2016) Matthew A. Dale et al.   JOURNAL OF IMMUNOLOGY

Effect of glucose on the biomechanical function of arterial elastin

(2015) Yunjie Wang et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mechanical factors direct mouse aortic remodelling during early maturation

(2015) V. P. Le et al.   Journal of the Royal Society Interface

Inhibition of Interleukin-1  Decreases Aneurysm Formation and Progression in a Novel Model of Thoracic Aortic Aneurysms

(2014) W. F. Johnston et al.   CIRCULATION

Arterial Stiffness and Hypertension

(2014) Gary F. Mitchell   HYPERTENSION

Fibulin-4 and fibulin-5 in elastogenesis and beyond: Insights from mouse and human studies

(2014) Christina L. Papke et al.   MATRIX BIOLOGY

Rapamycin Inhibits Smooth Muscle Cell Proliferation and Obstructive Arteriopathy Attributable to Elastin Deficiency

(2013) Wei Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Elastin-Derived Peptides Are New Regulators of Insulin Resistance Development in Mice

(2013) S. Blaise et al.   DIABETES

High-glucose levels and elastin degradation products accelerate osteogenesis in vascular smooth muscle cells

(2013) Aditi Sinha et al.   Diabetes & Vascular Disease Research

Elastic fibres in health and disease

(2013) Andrew K. Baldwin et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the BN Rat

(2013) Séverin Slove et al.   HYPERTENSION

Williams Syndrome Predisposes to Vascular Stiffness Modified by Antihypertensive Use and Copy Number Changes in NCF1

(2013) Beth A. Kozel et al.   HYPERTENSION

A Novel Cell Adhesion Region in Tropoelastin Mediates Attachment to Integrin αVβ5

(2013) Pearl Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutis laxa: Intersection of elastic fiber biogenesis, TGFβ signaling, the secretory pathway and metabolism

(2013) Zsolt Urban et al.   MATRIX BIOLOGY

Twenty patients including 7 probands with autosomal dominant cutis laxa confirm clinical and molecular homogeneity

(2013) Smail Hadj-Rabia et al.   Orphanet Journal of Rare Diseases

Matrix control of transforming growth factor-  function

(2012) M. Horiguchi et al.   JOURNAL OF BIOCHEMISTRY

Alternative Splicing and Tissue-specific Elastin Misassembly Act as Biological Modifiers of Human Elastin Gene Frameshift Mutations Associated with Dominant Cutis Laxa

(2012) Hideki Sugitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cytokine axis regulates elastin formation and degradation

(2012) Erin P. Sproul et al.   MATRIX BIOLOGY

Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice

(2011) Victoria P. Le et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness

(2011) Paige S. Katz et al.   BASIC RESEARCH IN CARDIOLOGY

New insights into the pathogenesis of autosomal-dominant cutis laxa with report of five ELN mutations

(2011) Bert Callewaert et al.   HUMAN MUTATION

Biomechanical and Microstructural Properties of Common Carotid Arteries from Fibulin-5 Null Mice

(2010) William Wan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Unraveling the mechanism of elastic fiber assembly: The roles of short fibulins

(2010) Hiromi Yanagisawa et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Williams–Beuren Syndrome

(2010) Barbara R. Pober   NEW ENGLAND JOURNAL OF MEDICINE

Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites

(2009) Robert N. Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A brief history of arterial wave mechanics

(2009) Kim H. Parker   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Fundamental role of axial stress in compensatory adaptations by arteries

(2008) J.D. Humphrey et al.   JOURNAL OF BIOMECHANICS

Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome

(2008) Barbara R. Pober et al.   JOURNAL OF CLINICAL INVESTIGATION