High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine

Gut microbiota are linked to increased susceptibility to hepatic steatosis in low-aerobic-capacity rats fed an acute high-fat diet

(2016) Matthew R. Panasevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Chasing a ghost? – Issues with the determination of circulating levels of endotoxin in human blood

(2016) Anne Gnauck et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

Disconnect between adipose tissue inflammation and cardiometabolic dysfunction in Ossabaw pigs

(2015) Victoria J. Vieira-Potter et al.   Obesity

STAMP: statistical analysis of taxonomic and functional profiles

(2014) Donovan H. Parks et al.   BIOINFORMATICS

Gut microbiome and nonalcoholic fatty liver diseases

(2014) Lixin Zhu et al.   PEDIATRIC RESEARCH

Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity

(2014) Ryan G. Toedebusch et al.   PHYSIOLOGICAL GENOMICS

Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences

(2014) Jai Ram Rideout et al.   PeerJ

Differential effects of low-fat and high-fat diets on fed-state hepatic triacylglycerol secretion, hepatic fatty acid profiles, and DGAT-1 protein expression in obese-prone Sprague–Dawley rats

(2013) Timothy D. Heden et al.   Applied Physiology Nutrition and Metabolism

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

(2013) Ling Yang et al.   HEPATOLOGY

Mechanism of IL-1  Modulation of Intestinal Epithelial Barrier Involves p38 Kinase and Activating Transcription Factor-2 Activation

(2013) R. Al-Sadi et al.   JOURNAL OF IMMUNOLOGY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Use of pigs as a potential model for research into dietary modulation of the human gut microbiota

(2013) Sonja N. Heinritz et al.   NUTRITION RESEARCH REVIEWS

Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine

(2013) Jaume Padilla et al.   PHYSIOLOGICAL GENOMICS

Characterisation of Gut Microbiota in Ossabaw and Göttingen Minipigs as Models of Obesity and Metabolic Syndrome

(2013) Rebecca Pedersen et al.   PLoS One

Molecular Characterization of the Fecal Microbiota in Patients with Nonalcoholic Steatohepatitis – A Longitudinal Study

(2013) Vincent Wai-Sun Wong et al.   PLoS One

piggyBac Transposon plus Insulators Overcome Epigenetic Silencing to Provide for Stable Signaling Pathway Reporter Cell Lines

(2013) Valeri V. Mossine et al.   PLoS One

Hepatic Fatty Acid Trafficking: Multiple Forks in the Road

(2013) Douglas G. Mashek   Advances in Nutrition

Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14

(2012) Shuhong Guo et al.   AMERICAN JOURNAL OF PATHOLOGY

Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides andde novosynthesized fatty acids in HepG2 cells

(2012) Haja R. Wurie et al.   FEBS Journal

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

A bioassay for determination of lipopolysaccharide in environmental samples

(2012) Marcus Peters et al.   Innate Immunity

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model

(2011) R. Scott Rector et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

Does physical inactivity cause nonalcoholic fatty liver disease?

(2011) R. Scott Rector et al.   JOURNAL OF APPLIED PHYSIOLOGY

LPS-binding Protein Enables Intestinal Epithelial Restitution Despite LPS Exposure

(2011) Juli M. Richter et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Bayesian community-wide culture-independent microbial source tracking

(2011) Dan Knights et al.   NATURE METHODS

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

(2010) R. Scott Rector et al.   JOURNAL OF HEPATOLOGY

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine

(2009) Lydia Lee et al.   HEPATOLOGY

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

(2009) Chenhong Zhang et al.   ISME Journal

Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats

(2008) R. Scott Rector et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Overproduction of Very Low–Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome

(2008) Martin Adiels et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe