Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans

A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence

(2015) Haiyi Lou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sea-level haemoglobin concentration is associated with greater exercise capacity in Tibetan males at 4200 m

(2015) P. D. Wagner et al.   EXPERIMENTAL PHYSIOLOGY

Altitude Adaptation: A Glimpse Through Various Lenses

(2015) Tatum S. Simonson   HIGH ALTITUDE MEDICINE & BIOLOGY

Low haemoglobin concentration in Tibetan males is associated with greater high-altitude exercise capacity

(2015) T. S. Simonson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Human high-altitude adaptation: forward genetics meets the HIF pathway

(2014) Abigail W. Bigham et al.   GENES & DEVELOPMENT

Defective Tibetan PHD2 Binding to p23 Links High Altitude Adaption to Altered Oxygen Sensing

(2014) Daisheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA

(2014) Emilia Huerta-Sánchez et al.   NATURE

A genetic mechanism for Tibetan high-altitude adaptation

(2014) Felipe R Lorenzo et al.   NATURE GENETICS

Shared and Unique Signals of High-Altitude Adaptation in Geographically Distinct Tibetan Populations

(2014) Tana Wuren et al.   PLoS One

Admixture facilitates genetic adaptations to high altitude in Tibet

(2014) Choongwon Jeong et al.   Nature Communications

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes

(2014) Nitin Udpa et al.   GENOME BIOLOGY

Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era

(2013) Nayia Petousi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Genomic Analysis of Natural Selection and Phenotypic Variation in High-Altitude Mongolians

(2013) Jinchuan Xing et al.   PLoS Genetics

Ethiopian Genetic Diversity Reveals Linguistic Stratification and Complex Influences on the Ethiopian Gene Pool

(2012) Luca Pagani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

Genetic Variants in EPAS1 Contribute to Adaptation to High-Altitude Hypoxia in Sherpas

(2012) Masayuki Hanaoka et al.   PLoS One

Genetic adaptation to high altitude in the Ethiopian highlands

(2012) Laura B Scheinfeldt et al.   GENOME BIOLOGY

’ome on the Range: Altitude Adaptation, Positive Selection, and Himalayan Genomics

(2011) Martin J. MacInnis et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Peopling the Tibetan Plateau: Insights from Archaeology

(2011) Mark Aldenderfer   HIGH ALTITUDE MEDICINE & BIOLOGY

Genetic determinants of Tibetan high-altitude adaptation

(2011) Tatum S. Simonson et al.   HUMAN GENETICS

A mitochondrial revelation of early human migrations to the Tibetan Plateau before and after the last glacial maximum

(2010) Zhendong Qin et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas

(2010) Y. Peng et al.   MOLECULAR BIOLOGY AND EVOLUTION

EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda

(2010) S. Aggarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes for High Altitudes

(2010) J. F. Storz   SCIENCE

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

(2010) Abigail Bigham et al.   PLoS Genetics