Defective Tibetan PHD2 Binding to p23 Links High Altitude Adaption to Altered Oxygen Sensing
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Defective Tibetan PHD2 Binding to p23 Links High Altitude Adaption to Altered Oxygen Sensing
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 21, Pages 14656-14665
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-04-08
DOI
10.1074/jbc.m113.541227
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Human adaptability studies at high altitude: Research designs and major concepts during fifty years of discovery
- (2013) Cynthia M. Beall AMERICAN JOURNAL OF HUMAN BIOLOGY
- Erythrocytosis and Pulmonary Hypertension in a Mouse Model of HumanHIF2AGain of Function Mutation
- (2013) Qiulin Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prolyl Hydroxylase Domain Protein 2 (PHD2) Binds a Pro-Xaa-Leu-Glu Motif, Linking It to the Heat Shock Protein 90 Pathway
- (2013) Daisheng Song et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Knock-in Mouse Model of HumanPHD2Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism
- (2013) Patrick R. Arsenault et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Tibetan-Specific Mutation in the Hypoxic Gene EGLN1 and Its Contribution to High-Altitude Adaptation
- (2013) Kun Xiang et al. MOLECULAR BIOLOGY AND EVOLUTION
- Recent human adaptation: genomic approaches, interpretation and insights
- (2013) Laura B. Scheinfeldt et al. NATURE REVIEWS GENETICS
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- The HIF Pathway and Erythrocytosis
- (2011) Frank S. Lee et al. Annual Review of Pathology-Mechanisms of Disease
- Genetic determinants of Tibetan high-altitude adaptation
- (2011) Tatum S. Simonson et al. HUMAN GENETICS
- Molecular Evolution of the Metazoan PHD–HIF Oxygen-Sensing System
- (2011) Kalle T. Rytkönen et al. MOLECULAR BIOLOGY AND EVOLUTION
- On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments
- (2011) Binbin Wang et al. PLoS One
- The Hexameric Structures of Human Heat Shock Protein 90
- (2011) Cheng-Chung Lee et al. PLoS One
- Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
- (2010) P. P. Kapitsinou et al. BLOOD
- The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
- (2010) Christoph Loenarz et al. EMBO REPORTS
- The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
- (2010) Michele M. Hickey et al. JOURNAL OF CLINICAL INVESTIGATION
- A Genome-Wide Search for Signals of High-Altitude Adaptation in Tibetans
- (2010) S. Xu et al. MOLECULAR BIOLOGY AND EVOLUTION
- Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas
- (2010) Y. Peng et al. MOLECULAR BIOLOGY AND EVOLUTION
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- HSP90 at the hub of protein homeostasis: emerging mechanistic insights
- (2010) Mikko Taipale et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders
- (2010) C. M. Beall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Evidence for High-Altitude Adaptation in Tibet
- (2010) T. S. Simonson et al. SCIENCE
- Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
- (2010) X. Yi et al. SCIENCE
- Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data
- (2010) Abigail Bigham et al. PLoS Genetics
- Universal sample preparation method for proteome analysis
- (2009) Jacek R Wiśniewski et al. NATURE METHODS
- Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 mutation
- (2008) D. P. Gale et al. BLOOD
- Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
- (2008) Adam T. Boutin et al. CELL
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- A Gain-of-Function Mutation in theHIF2AGene in Familial Erythrocytosis
- (2008) Melanie J. Percy et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started