Social stress shortens lifespan in mice

Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women

(2017) Silvia Stringhini et al.   LANCET

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential

(2017) Priya Balasubramanian et al.   EBioMedicine

Age-associated vascular inflammation promotes monocytosis during atherogenesis

(2016) Wei Du et al.   AGING CELL

The Association Between Income and Life Expectancy in the United States, 2001-2014

(2016) Raj Chetty et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Out with the old

(2016) Jesús Gil et al.   NATURE

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

(2016) B. G. Childs et al.   SCIENCE

Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice

(2016) Valentina Sanghez et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Cumulative early life adversity predicts longevity in wild baboons

(2016) Jenny Tung et al.   Nature Communications

Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis

(2016) Maria Razzoli et al.   Molecular Metabolism

Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease

(2016) Vera H. I. Fengler et al.   PLoS One

Chronic intermittent mental stress promotes atherosclerotic plaque vulnerability, myocardial infarction and sudden death in mice

(2015) Lynn Roth et al.   ATHEROSCLEROSIS

Reduced Expression of MYC Increases Longevity and Enhances Healthspan

(2015) Jeffrey W. Hofmann et al.   CELL

Sex differences and stress across the lifespan

(2015) Tracy L Bale et al.   NATURE NEUROSCIENCE

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

(2015) E. H. Blackburn et al.   SCIENCE

Longevity factor klotho and chronic psychological stress

(2015) A A Prather et al.   Translational Psychiatry

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and Longevity

(2014) E. S. Epel et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Chronic variable stress activates hematopoietic stem cells

(2014) Timo Heidt et al.   NATURE MEDICINE

Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: A translational approach

(2014) Jan-Michael Heinzmann et al.   PSYCHONEUROENDOCRINOLOGY

Chronic Stress Impairs Collateral Blood Flow Recovery in Aged Mice

(2014) Roberta M. Lassance-Soares et al.   Journal of Cardiovascular Translational Research

The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet

(2014) Sarah J. Mitchell et al.   Cell Reports

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

A new murine model of stress-induced complex atherosclerotic lesions

(2013) A. H. Najafi et al.   Disease Models & Mechanisms

Telomere Length in Epidemiology: A Biomarker of Aging, Age-Related Disease, Both, or Neither?

(2013) J. L. Sanders et al.   EPIDEMIOLOGIC REVIEWS

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

(2013) Albert R. Davalos et al.   JOURNAL OF CELL BIOLOGY

Chronic social stress during adolescence: Interplay of paroxetine treatment and ageing

(2013) Sebastian H. Scharf et al.   NEUROPHARMACOLOGY

Conditional Deletion of ERK5 MAP Kinase in the Nervous System Impairs Pheromone Information Processing and Pheromone-Evoked Behaviors

(2013) Junhui Zou et al.   PLoS One

Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome

(2013) Valentina Sanghez et al.   PSYCHONEUROENDOCRINOLOGY

Socioeconomic Status, Structural and Functional Measures of Social Support, and Mortality

(2012) Silvia Stringhini et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Pathobiology of Aging Mice and GEM

(2012) C. F. Brayton et al.   VETERINARY PATHOLOGY

A quantitative PCR method for measuring absolute telomere length

(2011) Nathan J O'Callaghan et al.   BIOLOGICAL PROCEDURES ONLINE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Stress revisited: A critical evaluation of the stress concept

(2011) J.M. Koolhaas et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The metabolic footprint of aging in mice

(2011) Riekelt H. Houtkooper et al.   Scientific Reports

Multiple risk exposure as a potential explanatory mechanism for the socioeconomic status-health gradient

(2010) Gary W. Evans et al.   Annals of the New York Academy of Sciences

Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice

(2010) A. Bartolomucci et al.   Disease Models & Mechanisms

Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice

(2010) Harold Dadomo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Social stress, visceral obesity, and coronary artery atherosclerosis: product of a primate adaptation

(2009) Carol A. Shively et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Metabolic Consequences and Vulnerability to Diet-Induced Obesity in Male Mice under Chronic Social Stress

(2009) Alessandro Bartolomucci et al.   PLoS One