Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14

Ageing is associated with brown adipose tissue remodelling and loss of white fat browning in female C57BL/6 mice

(2017) Leidyanne Ferreira Gonçalves et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

(2016) Juliana Camacho-Pereira et al.   Cell Metabolism

Effect of gender on perioperative outcomes after robotic-assisted pulmonary lobectomy

(2016) Jessica R. Glover et al.   Journal of Thoracic Disease

The sirtuins, oxidative stress and aging: an emerging link

(2016) Philip I. Merksamer et al.   Aging-US

Characterization of the SIRT family of NAD+-dependent protein deacetylases in the context of a mammalian model of hibernation, the thirteen-lined ground squirrel

(2015) Andrew N. Rouble et al.   CRYOBIOLOGY

The metabolic regulation of aging

(2015) Toren Finkel   NATURE MEDICINE

SIRT3 regulates progression and development of diseases of aging

(2015) Eoin McDonnell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

(2015) Mickaël Ohanna et al.   Oncotarget

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

(2014) Eija Pirinen et al.   Cell Metabolism

High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients

(2014) Xiaojing Chen et al.   Scientific Reports

Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione

(2013) Dan Nguyen et al.   AGING CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH

(2013) Akiko Satoh et al.   Cell Metabolism

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice

(2013) Tsutomu Sasaki et al.   DIABETOLOGIA

Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain

(2013) Paul R. Evans et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

(2013) L. E. Hebert et al.   NEUROLOGY

GRK2 contribution to the regulation of energy expenditure and brown fat function

(2012) Rocio Vila-Bedmar et al.   FASEB JOURNAL

Assembly and Function of the Regulator of G protein Signaling 14 (RGS14)·H-Ras Signaling Complex in Live Cells Are Regulated by Gαi1and Gαi-linked G Protein-coupled Receptors

(2012) Christopher P. Vellano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial Metabolism, Sirtuins, and Aging

(2012) M. N. Sack et al.   Cold Spring Harbor Perspectives in Biology

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

(2010) Laurent Mouchiroud et al.   AGING CELL

Mitochondrial energy metabolism and ageing

(2010) Ivana Bratic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-γ activation and function in lipid homeostasis and energy expenditure

(2010) Daozhong Jin et al.   FASEB JOURNAL

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

(2010) S. E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Obesity: Why be Concerned?

(2009) W. Virgil Brown et al.   AMERICAN JOURNAL OF MEDICINE

The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis

(2009) Daphne P Guh et al.   BMC PUBLIC HEALTH

RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways

(2009) Feng-jue Shu et al.   CELLULAR SIGNALLING

Human longevity and 11p15.5: a study in 1321 centenarians

(2009) Francesco Lescai et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Role of Layer 6 of V2 Visual Cortex in Object-Recognition Memory

(2009) Manuel F. López-Aranda et al.   SCIENCE