Long-lasting pathological consequences of overexpression-induced α-synuclein spreading in the rat brain

Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration

(2017) Itzia Jimenez-Ferrer et al.   NEUROBIOLOGY OF DISEASE

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections

(2016) Ayse Ulusoy et al.   ACTA NEUROPATHOLOGICA

Autosomal dominant Parkinson's disease caused by SNCA duplications

(2016) Takuya Konno et al.   PARKINSONISM & RELATED DISORDERS

Phenotypic spectrum of alpha-synuclein mutations: New insights from patients and cellular models

(2016) Simona Petrucci et al.   PARKINSONISM & RELATED DISORDERS

Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice

(2015) Michael Helwig et al.   BRAIN

Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

(2015) Rosalind F. Roberts et al.   BRAIN

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

(2015) Nishant N. Vaikath et al.   NEUROBIOLOGY OF DISEASE

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

(2014) Edward Rockenstein et al.   BRAIN

Morphometric characterization of microglial phenotypes in human cerebral cortex

(2014) Susana G Torres-Platas et al.   Journal of Neuroinflammation

Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

(2013) Nolwen L. Rey et al.   ACTA NEUROPATHOLOGICA

Homeostatic and injury-induced microglia behavior in the aging brain

(2013) Jasmin K. Hefendehl et al.   AGING CELL

Caudo-rostral brain spreading of α-synuclein through vagal connections

(2013) Ayse Ulusoy et al.   EMBO Molecular Medicine

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

(2013) Changyoun Kim et al.   Nature Communications

α-Synuclein Elevation in Human Neurodegenerative Diseases: Experimental, Pathogenetic, and Therapeutic Implications

(2012) Ayse Ulusoy et al.   MOLECULAR NEUROBIOLOGY

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease

(2010) Vanesa Sanchez-Guajardo et al.   PLoS One

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic investigation of α-synuclein multiplication and parkinsonism

(2008) Owen A. Ross et al.   ANNALS OF NEUROLOGY