Review
Cell Biology
Susana Lopez-Ortiz, Simone Lista, Saul Penin-Grandes, Jose Pinto-Fraga, Pedro L. Valenzuela, Robert Nistico, Enzo Emanuele, Alejandro Lucia
Summary: This study aims to review the definitions and methods used for the assessment of intrinsic capacity (IC) in older adults. While there is overall consensus on the definition and dimensions of IC, there is substantial variation in the assessment methods, and no consensus on the best way to compute a comprehensive score to evaluate IC.
AGEING RESEARCH REVIEWS
(2022)
Article
Geriatrics & Gerontology
Paul D. Meesters
Summary: The number of elderly people with schizophrenia aged 65 years and above is increasing, posing challenges to the existing care systems. Research on schizophrenia in later life has been limited, but recent years have seen a significant increase in novel and high-quality studies. Older people with schizophrenia include those who had an early onset and aged with the disorder, as well as a smaller but significant group with a late onset. With aging, physical needs become more important and medical comorbidity contributes to higher mortality. Symptoms and functioning fluctuate with time, leading to deterioration in some but improvement in others. It is worth noting that a substantial number of older people may experience subjective well-being despite ongoing symptoms and social impairments. Many individuals with schizophrenia live in the community, but when institutionalization is needed, they are often placed in residential or nursing homes where staff is ill-equipped to address their complex needs. There is a need for new care models that integrate mental health and general health systems.
Editorial Material
Geriatrics & Gerontology
Jean Woo
Summary: Populations in Asian developed economies are rapidly ageing, resulting in increased frailty and dependency. Consideration of social determinants is crucial in designing equitable health and social care systems. Asian countries are developing integrated medical social care, with funding provided by long-term care insurance and philanthropy.
Article
Nutrition & Dietetics
Mirta Crovetto Mattassi, Camila Henriquez Mella, Lissette Perez Bocaz
Summary: This study investigated sarcopenia and nutritional status in Chilean older adults aged 65 and older. The results showed that nearly 50% of the participants had probable sarcopenia, with obese individuals having a higher risk. There is an association between nutritional status and sarcopenia.
Article
Multidisciplinary Sciences
Dan Su, Xiaojun Zhang, Yanling Su, Piu Chan, Erhe Xu
Summary: This study aimed to explore the effects of different levodopa doses on blood pressure in older patients with PD in the early and middle stages. The results showed that 250 mg or more of levodopa/benserazide significantly reduced BP in the lying and standing positions. Mild cognitive impairment was a risk factor for orthostatic hypotension occurrence in the off state. Therefore, older patients with PD should routinely monitor their BP.
Editorial Material
Geriatrics & Gerontology
Jotheeswaran Amuthavalli Thiyagarajan, Christopher Mikton, Rowan H. Harwood, Muthoni Gichu, Victor Gaigbe-Togbe, Tapiwa Jhamba, Daniela Pokorna, Valentina Stoevska, Rio Hada, Grace Sanico Steffan, Ana Liena, Eileen Rocard, Theresa Diaz
Summary: Life expectancy has increased significantly in the past 100 years, but the health of older people remains a concern. The UN Decade of Healthy Ageing was adopted in 2020 to address this issue, but there is a lack of goals and guidance for the program. The establishment of the Technical Advisory Group for Measurement of Healthy Ageing aims to provide support in monitoring and evaluating the progress of the Decade.
Review
Geriatrics & Gerontology
Victoria A. Goodwin, Abi J. Hall, Alison Bethel, Emily Taylor, Lynn Tatnell, Malcolm Turner, Julia Frost
Summary: There has been limited research on joy among older people in the literature. This scoping review aimed to understand the existing evidence on joy and older people. Searches were conducted in ten databases and 11 papers were included in the review, involving 1,487 participants. The findings highlight the importance of social connections and meaningful activities as sources of joy for older people.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Multidisciplinary Sciences
Lewis A. Ingram, Vincent K. Carroll, Annie A. Butler, Matthew A. Brodie, Simon C. Gandevia, Stephen R. Lord
Summary: The study evaluated the validity of the upper limb Physiological Profile Assessment (PPA) in people with Parkinson's disease (PD) and found that the PPA can effectively differentiate PD patients from healthy controls and detect differences in upper limb test domains between different medication states. Six key tests, including handgrip strength, finger-press reaction time, 9-hole peg test, bimanual pole test, arm stability, and shirt buttoning, were identified for assessing upper limb function in PD patients. These findings suggest that clinical assessments in PD patients should prioritize tests of muscle strength, unilateral movement and dexterity, bimanual coordination, arm stability and functional tasks.
Article
Clinical Neurology
Stefania Diaconu, Laura Irincu, Diana Tint, Cristian Falup-Pecurariu
Summary: This study aimed to assess the effects of levodopa-carbidopa intestinal gel (LCIG) on sleep in people with advanced Parkinson's disease (PD). The findings demonstrated that LCIG infusion had beneficial effects on sleep parameters and sleep quality, which were consistent over a period of 12 months.
FRONTIERS IN NEUROLOGY
(2023)
Article
Geriatrics & Gerontology
Mariela Silberman-Beltramella, Alba Ayala, Carmen Rodriguez-Blazquez, Maria Joao Forjaz
Summary: This study examined social relationships and their association with health variables among individuals aged 50 and over in Spain. The results showed that loneliness was the main social aspect that impacted health status. The findings suggest the importance of developing public health policies focused on enhancing social characteristics that promote the health of older people.
Article
Social Sciences, Interdisciplinary
Pui Ling Ada Cheung
Summary: With the ageing of society, old-age care in urban China has become a major concern. A qualitative study in Beijing and Guangzhou shows that older people use resilience to cope with changing family support by adapting psychologically, contributing to their children's family, filling the gap with external resources and exercising their ability to choose their living arrangement. The impact on their well-being has been mitigated by their financial independence and the influence of new values. The research highlights the need for services and networks to support older people in the community, particularly in home care.
SOCIAL INDICATORS RESEARCH
(2023)
Article
Urban Studies
Joost van Hoof, Rudy F. M. van den Hoven, Moritz Hess, Willeke H. van Staalduinen, Loes M. T. Hulsebosch-Janssen, Jeroen Dikken
Summary: The Hague has been a member of the WHO's Global Network for Age-Friendly Cities and Communities since 2015. A survey commissioned by the municipality investigated older citizens' perceptions of the age-friendliness of their city. The findings revealed different perceptions among older people and suggested the need for policy adjustments.
Review
Medicine, General & Internal
Bastiaan R. Bloem, Michael S. Okun, Christine Klein
Summary: Parkinson's disease is a neurodegenerative condition with diverse causes and clinical presentations. Diagnosis is clinically based, and treatment goals vary from person to person, emphasizing the need for personalized management. Currently, there is no therapy to slow down or arrest the progression of Parkinson's disease.
Article
Clinical Neurology
Lara Hansen, Victoria Witzig, Joerg B. Schulz, Florian Holtbernd
Summary: This study analyzed data from the multinational Parkinson's Real-World Impact Assessment (PRISM) trial in six European countries and identified significant socio-economic factors affecting prescription patterns. The results showed that patient age, disease duration, and country of residence were predictors of treatment class, with younger patients being less likely to receive LD monotherapy and variation in prescription patterns across countries.
NEUROLOGICAL SCIENCES
(2023)
Review
Clinical Neurology
Stefanie Jost, Marie-Ann Kaldenbach, Angelo Antonini, Pablo Martinez-Martin, Lars Timmermann, Per Odin, Regina Katzenschlager, Rupam Borgohain, Alfonso Fasano, Fabrizio Stocchi, Nobutaka Hattori, Prashanth Lingappa Kukkle, Mayela Rodriguez-Violante, Cristian Falup-Pecurariu, Sebastian Schade, Jan Niklas Petry-Schmelzer, Vinod Metta, Daniel Weintraub, Guenther J. Deuschl, Alberto J. Espay, Eng-King Tan, Roongroj Bhidayasiri, Victor S. C. Fung, Francisco Cardoso, Claudia Trenkwalder, Peter Jenner, K. S. Ray Chaudhuri, Haidar Dafsari
Summary: This study reviewed the investigations on drug therapy for Parkinson's disease since 2010 and proposed a new drug conversion formula. These conversion formulas can help us compare drug regimens across different clinical trials. The results are important for studying the pharmacological efficacy of Parkinson's disease treatments as well as other non-pharmacological interventions.
MOVEMENT DISORDERS
(2023)
Article
Geriatrics & Gerontology
Annette Hand, Lloyd Louis Oates, William Keith Gray, Richard W. Walker
AGING & MENTAL HEALTH
(2019)
Article
Geriatrics & Gerontology
Peter Brock, James M. Fisher, Annette Hand, Richard W. Walker
Article
Geriatrics & Gerontology
Roshan Sebastian, William K. Gray, Aishling Foley, Lydia Trendall, Doori Oh, Annette Hand, Steve Dodds, Elliot McClenaghan, Vasco Dos Santos, Lloyd L. Oates, James Fisher, Richard W. Walker
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
(2020)
Article
Medicine, General & Internal
Sarah Brown, Sonia Michelle Dalkin, Angela Bate, Russ Bradford, Charlotte Allen, Katie Brittain, Amanda Clarke, Annette Hand
Article
Education & Educational Research
Fiona Osborne, Miles Harrison, James Fisher, Belinda Bateman
Summary: The use of medical reality television in providing authentic experiences of patient care is an intriguing yet under-researched modality in medical education. Students expressed a diverse range of emotions while watching the television clips and identified gaps in their clinical knowledge. However, they also reported increased engagement and promotion of holistic care practices through this modality.
BMC MEDICAL EDUCATION
(2021)
Article
Geriatrics & Gerontology
Annette Hand, Lloyd L. Oates, William K. Gray, Lorelle L. Dismore, Katherine Baker, Jenni Naisby, Richard W. Walker
Summary: This study investigated predictors of caregiver strain and its impact on care home placement for individuals with moderate to advanced Parkinsonism through a mixed methods approach. Findings suggest that factors such as functional disability and poor caregiver sleep influence caregiver strain. The development of a predictive model can help better understand caregiver strain in this population.
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
(2022)
Article
Neurosciences
Peter Brock, Lloyd L. Oates, William K. Gray, Emily J. Henderson, Helen Mann, Victoria J. Haunton, Rob Skelly, Annette Hand, Matthew L. Davies, Richard W. Walker
Summary: This study aimed to assess patient views on the impact of PD on their driving ability, as well as the consequences of these changes and how they manage them. A survey was conducted with 805 PD patients, revealing that losing a driving license had negative effects on employment, socialization, travel expenses, and lifestyle choices. Participants suggested managing changes in driving ability through planning, vehicle adaptions, maintaining skills, and self-assessment.
JOURNAL OF PARKINSONS DISEASE
(2022)
Article
Medicine, Research & Experimental
James Fisher, Charlotte Rothwell
Summary: This study explored medical students' experiences of participating in medical education research using Pierre Bourdieu's theory of practice. The findings revealed that medical students had a positive attitude towards participation, but had uncertainties about their roles. They perceived participation as beneficial to themselves, but also experienced "research fatigue". Students sometimes participated in research to maintain valued relationships with senior colleagues.
Article
Economics
K. Ray Chaudhuri, Annette Hand, Fallon Obam, Jonathan Belsey
Summary: The study shows that adding the Parkinson's KinetiGraph (PKG) to routine assessments for Parkinson's disease is a cost-effective intervention. It reduces costs, improves quality-adjusted life years, and allows for better assessment of motor symptoms in patients, leading to improved outcomes.
JOURNAL OF MEDICAL ECONOMICS
(2022)
Article
Geriatrics & Gerontology
Daniel Rippon, Annette Hand, Lorelle Dismore, Roberta Caiazza
Summary: This study explored the impact of the COVID-19 pandemic on informal caregivers of People with Parkinson's disease (PwP) and found that COVID-19 affected their vulnerabilities, home maintenance activities, and engagement with healthcare services.
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
(2023)
Meeting Abstract
Clinical Neurology
A. Hand, K. McEwan, A. Clarke, A. Bate, S. Dalkin, R. Bradford, C. Allen, K. McDonald, S. McCarthy, K. Brittain
MOVEMENT DISORDERS
(2022)
Meeting Abstract
Clinical Neurology
A. Hand, K. McEwan, A. Clarke, S. Dalkin, A. Bate, R. Bradford, C. Allen, K. McDonald, S. McCarthy, K. Brittain
MOVEMENT DISORDERS
(2022)
Review
Geriatrics & Gerontology
Song Yuin Lee, James Fisher, Anne P. F. Wand, Koen Milisen, Elke Detroyer, Sanjeev Sockalingam, Meera Agar, Annmarie Hosie, Andrew Teodorczuk
EUROPEAN GERIATRIC MEDICINE
(2020)
Article
Medicine, Research & Experimental
Ashley Scott, Mark Sudlow, Emily Shaw, James Fisher
