Microengineered Bioartificial Liver Chip for Drug Toxicity Screening

Computational Models for Human and Animal Hepatotoxicity with a Global Application Scope

(2016) Denis Mulliner et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates

(2016) Volker M. Lauschke et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes

(2016) Jacek R. Wiśniewski et al.   Journal of Proteomics

A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity

(2016) Suraj J Patel et al.   Clinical and Translational Gastroenterology

Liver sinusoid on a chip: Long-term layered co-culture of primary rat hepatocytes and endothelial cells in microfluidic platforms

(2015) Young Bok Abraham Kang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Heparin hydrogel sandwich cultures of primary hepatocytes

(2015) Elena Foster et al.   EUROPEAN POLYMER JOURNAL

Alternatives to animal testing: A review

(2015) Sonali K. Doke et al.   SAUDI PHARMACEUTICAL JOURNAL

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

(2013) L. Schyschka et al.   ARCHIVES OF TOXICOLOGY

Underlying potential: cellular and molecular determinants of adult liver repair

(2013) Anna Mae Diehl et al.   JOURNAL OF CLINICAL INVESTIGATION

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

(2013) Abhinav Bhushan et al.   Stem Cell Research & Therapy

Silicon Micromachining: Electrochemical Micromachining as an Enabling Technology for Advanced Silicon Microstructuring (Adv. Funct. Mater. 6/2012)

(2012) Margherita Bassu et al.   ADVANCED FUNCTIONAL MATERIALS

A preliminary study for constructing a bioartificial liver device with induced pluripotent stem cell-derived hepatocytes

(2012) Masaya Iwamuro et al.   Biomedical Engineering Online

Assessment of Compound Hepatotoxicity Using Human Plateable Cryopreserved Hepatocytes in a 1536-Well-Plate Format

(2011) Timothy A. Moeller et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Improvement of HepG2/C3a cell functions in a microfluidic biochip

(2011) Jean Matthieu Prot et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microfluidic devices for in vitro studies on liver drug metabolism and toxicity

(2011) Paul M. van Midwoud et al.   Integrative Biology

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

(2010) Mihye Kim et al.   BIOMATERIALS

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Reactive Epoxy-Functionalized Thin Films by a Pulsed Plasma Polymerization Process

(2008) Benjamin Thierry et al.   LANGMUIR