Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

(2014) Olivia Dean et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment

(2014) Piotr Gałecki et al.   Pharmacological Reports

The promise of N-acetylcysteine in neuropsychiatry

(2013) Michael Berk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test

(2012) Viviane M. Linck et al.   BEHAVIOURAL PHARMACOLOGY

Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state

(2012) Kerstin Kojer et al.   EMBO JOURNAL

Involvement of different types of potassium channels in the antidepressant-like effect of ascorbic acid in the mouse tail suspension test

(2012) Morgana Moretti et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Maternal N-acetyl-cysteine (NAC) protects the rat fetal brain from inflammatory cytokine responses to lipopolysaccharide (LPS)

(2012) Ron Beloosesky et al.   Journal of Maternal-Fetal & Neonatal Medicine

A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

(2012) Frederick Rohan Walker   NEUROPHARMACOLOGY

Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder

(2012) Guilherme A. Behr et al.   Oxidative Medicine and Cellular Longevity

N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: Behavioral and biochemical analyses in rats

(2012) Irena Smaga et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

(2011) Brian Leonard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

(2011) Bun-Hee Lee et al.   Psychiatry Investigation

α-Tocopherol administration produces an antidepressant-like effect in predictive animal models of depression

(2010) Kelly R. Lobato et al.   BEHAVIOURAL BRAIN RESEARCH

Possible Involvement of Signal Transducers and Activators of Transcription 3 System on Depression in the Model Mice Brain

(2010) Salin Mingmalairak et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

(2010) Jeremy W. Gawryluk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease

(2010) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Depression and oxidative damage to lipids

(2010) Sarah Yager et al.   PSYCHONEUROENDOCRINOLOGY

The effect ofN-acetylcysteine on amphetamine-mediated dopamine release in rat brain striatal slices by ion-pair reversed-phase high performance liquid chromatography

(2009) Erzsébet Gere-Pászti et al.   BIOMEDICAL CHROMATOGRAPHY

Oxidative stress parameters after combined fluoxetine and acetylsalicylic acid therapy in depressive patients

(2009) Piotr Gałecki et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism

(2009) Ellisa Parker-Athill et al.   JOURNAL OF NEUROIMMUNOLOGY

Antidepressant-like effects of N-acetyl-L-cysteine in rats

(2008) Frederico F. Ferreira et al.   BEHAVIOURAL PHARMACOLOGY

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial

(2008) Michael Berk et al.   BIOLOGICAL PSYCHIATRY

N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial

(2008) Michael Berk et al.   BIOLOGICAL PSYCHIATRY

S-Glutathionylation Impairs Signal Transducer and Activator of Transcription 3 Activation and Signaling

(2008) Yi Xie et al.   ENDOCRINOLOGY

Interferon-α-induced serotonin uptake in Jurkat T cells via mitogen-activated protein kinase and transcriptional regulation of the serotonin transporter

(2008) C-W. Tsao et al.   JOURNAL OF PSYCHOPHARMACOLOGY

In vivo antioxidant status: A putative target of antidepressant action

(2008) Ayesha Zafir et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased plasma levels of 8-iso-PGF2α and IL-6 in an elderly population with depression

(2008) Nikolaos Dimopoulos et al.   PSYCHIATRY RESEARCH

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus

(2007) Lêda S.B. Garcia et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY