Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder

Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment

(2014) Piotr Gałecki et al.   Pharmacological Reports

Impact of fluoxetine on liver damage in rats

(2014) Iwona Inkielewicz-Stępniak   Pharmacological Reports

Effects of Fluoxetine on the Oxidative Status of Peripheral Blood Leucocytes of Restraint-Stressed Mice

(2011) Silvia Novío et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Fluoxetine affects antioxidant system and promotes apoptotic signaling in Wistar rat liver

(2011) Jelena Djordjevic et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pathobiological targets of depression

(2011) Kanwaljit Chopra et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Prefrontal cortex glutathione S-transferase levels in patients with bipolar disorder, major depression and schizophrenia

(2011) Jeremy W. Gawryluk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Administration of memantine and imipramine alters mitochondrial respiratory chain and creatine kinase activities in rat brain

(2011) Gislaine Z. Réus et al.   JOURNAL OF NEURAL TRANSMISSION

Antidepressant-like effect of a Ginkgo biloba extract (EGb761) in the mouse forced swimming test: Role of oxidative stress

(2011) Patricia Rojas et al.   NEUROCHEMISTRY INTERNATIONAL

Harmine and Imipramine Promote Antioxidant Activities in Prefrontal Cortex and Hippocampus

(2011) Gislaine Z. Réus et al.   Oxidative Medicine and Cellular Longevity

Venlafaxine protects against stress-induced oxidative DNA damage in hippocampus during antidepressant testing in mice

(2011) Basel A. Abdel-Wahab et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of long-term antidepressant treatment on oxidative status in major depressive disorder: A 24-week follow-up study

(2011) Vahap Ozan Kotan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Free radicals and antioxidants – quo vadis?

(2011) Barry Halliwell   TRENDS IN PHARMACOLOGICAL SCIENCES

α-Tocopherol administration produces an antidepressant-like effect in predictive animal models of depression

(2010) Kelly R. Lobato et al.   BEHAVIOURAL BRAIN RESEARCH

The antidepressant action of imipramine and venlafaxine involves suppression of nitric oxide synthesis

(2010) M. Krass et al.   BEHAVIOURAL BRAIN RESEARCH

Involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test

(2010) Andréa D.E. Zomkowski et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

(2010) Jeremy W. Gawryluk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A systemic toxicity index developed to assess peripheral changes in mood episodes

(2010) F Kapczinski et al.   MOLECULAR PSYCHIATRY

Temporal Lobe Atrophy and White Matter Lesions are Related to Major Depression over 5 years in the Elderly

(2010) Pernille J Olesen et al.   NEUROPSYCHOPHARMACOLOGY

Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders

(2010) Ann Gardner et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Expression of oxidative stress-response genes is not activated in the prefrontal cortex of patients with depressive disorder

(2010) Jean-Raymond Teyssier et al.   PSYCHIATRY RESEARCH

Increased xanthine oxidase in the thalamus and putamen in depression

(2010) Tanja Maria Michel et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Using Isoprostanes as Biomarkers of Oxidative Stress: Some Rarely Considered Issues

(2009) Barry Halliwell et al.   ANTIOXIDANTS & REDOX SIGNALING

Changes of Brain Morphometry in First-Episode, Drug-Naïve, Non–Late-Life Adult Patients with Major Depression: An Optimized Voxel-Based Morphometry Study

(2009) Ke Zou et al.   BIOLOGICAL PSYCHIATRY

Total antioxidant capacity and total oxidant status in patients with major depression: Impact of antidepressant treatment

(2009) Birgul Elbozan Cumurcu et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Cellular Defenses against Superoxide and Hydrogen Peroxide

(2008) James A. Imlay   Annual Review of Biochemistry

Antidepressant-like effect of liquiritin from Glycyrrhiza uralensis in chronic variable stress induced depression model rats

(2008) Zhiyu Zhao et al.   BEHAVIOURAL BRAIN RESEARCH

Antidepressant-like effect of the organoselenium compound ebselen in mice: Evidence for the involvement of the monoaminergic system

(2008) Thaís Posser et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Illness duration and total brain gray matter in bipolar disorder: Evidence for neurodegeneration?

(2008) Benicio N. Frey et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Effects of antidepressants on mRNA levels of antioxidant enzymes in human monocytic U-937 cells

(2008) Andreas Johannes Schmidt et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

In vivo antioxidant status: A putative target of antidepressant action

(2008) Ayesha Zafir et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased plasma levels of 8-iso-PGF2α and IL-6 in an elderly population with depression

(2008) Nikolaos Dimopoulos et al.   PSYCHIATRY RESEARCH

Nortriptyline Protects Mitochondria and Reduces Cerebral Ischemia/Hypoxia Injury

(2008) Wen-hua Zhang et al.   STROKE