Cancer diagnostics: On-target probes for early detection

Ultrasensitive tumour-penetrating nanosensors of protease activity

(2017) Ester J. Kwon et al.   Nature Biomedical Engineering

Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia

(2017) Xianchuang Zheng et al.   Nature Biomedical Engineering

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

(2016) Melodi Javid Whitley et al.   Science Translational Medicine

Mathematical framework for activity-based cancer biomarkers

(2015) Gabriel A. Kwong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting cancers through tumor-activatable minicircles that lead to a detectable blood biomarker

(2015) John A. Ronald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo

(2015) Xianchuang Zheng et al.   Nature Communications

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

(2012) Gabriel A Kwong et al.   NATURE BIOTECHNOLOGY

Early Diagnosis of Ovarian Carcinoma: Is a Solution in Sight?

(2011) Amelie M. Lutz et al.   RADIOLOGY

Mathematical Model Identifies Blood Biomarker-Based Early Cancer Detection Strategies and Limitations

(2011) S. S. Hori et al.   Science Translational Medicine

Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes

(2008) Yasuteru Urano et al.   NATURE MEDICINE

Cancer Screening: A Mathematical Model Relating Secreted Blood Biomarker Levels to Tumor Sizes

(2008) Amelie M Lutz et al.   PLOS MEDICINE