Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice

Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice

(2015) Nandini Singh et al.   DEVELOPMENTAL DYNAMICS

Definition of Critical Periods for Hedgehog Pathway Antagonist-Induced Holoprosencephaly, Cleft Lip, and Cleft Palate

(2015) Galen W. Heyne et al.   PLoS One

Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly

(2014) Edward J. Johnson et al.   DEVELOPMENTAL BIOLOGY

Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology

(2014) N. Singh et al.   Disease Models & Mechanisms

Characterization of Subtle Brain Abnormalities in a Mouse Model of Hedgehog Pathway Antagonist-Induced Cleft Lip and Palate

(2014) Robert J. Lipinski et al.   PLoS One

Targeting of Smoothened for therapeutic gain

(2014) Martial Ruat et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Size Does Not Always Matter: Ts65Dn Down Syndrome Mice Show Cerebellum-Dependent Motor Learning Deficits that Cannot Be Rescued by Postnatal SAG Treatment

(2013) N. Gutierrez-Castellanos et al.   JOURNAL OF NEUROSCIENCE

Reagents for developmental regulation of Hedgehog signaling

(2013) Cristy Lewis et al.   METHODS

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

(2013) I. Das et al.   Science Translational Medicine

Human limb abnormalities caused by disruption of hedgehog signaling

(2012) Eve Anderson et al.   TRENDS IN GENETICS

Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord

(2011) Y. H. Belgacem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Small-Molecule Smoothened Agonist Prevents Glucocorticoid-Induced Neonatal Cerebellar Injury

(2011) V. M. Heine et al.   Science Translational Medicine

Vertebrate limb bud development: moving towards integrative analysis of organogenesis

(2009) Rolf Zeller et al.   NATURE REVIEWS GENETICS