Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells

Requirement and Epigenetics Reprogramming of Nrf2 in Suppression of Tumor Promoter TPA-Induced Mouse Skin Cell Transformation by Sulforaphane

(2014) Z.-Y. Su et al.   Cancer Prevention Research

The Role of E-Cadherin Down-Regulation in Oral Cancer: CDH1 Gene Expression and Epigenetic Blockage

(2014) G. Pannone et al.   CURRENT CANCER DRUG TARGETS

Synergistic chromatin repression of the tumor suppressor geneRARBin human prostate cancers

(2014) Céline Moison et al.   Epigenetics

Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells

(2014) Qi Xie et al.   GENES CHROMOSOMES & CANCER

Tumor-suppressor Gene Promoter Hypermethylation in Saliva of Head and Neck Cancer Patients

(2014) Dmitry A. Ovchinnikov et al.   Translational Oncology

Evidence for a Functional Link between Chromosomal Breakpoints and Aberrant DNA Methylation in Cancer

(2014) Sven Bilke et al.   Frontiers in Oncology

Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer

(2013) Ganji Purnachandra Nagaraju et al.   CANCER LETTERS

Gene methylation in gastric cancer

(2013) Yiping Qu et al.   CLINICA CHIMICA ACTA

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

(2013) Praveen Rajendran et al.   Epigenetics

Genome-Wide Methylation Analysis and Epigenetic Unmasking Identify Tumor Suppressor Genes in Hepatocellular Carcinoma

(2013) Kate Revill et al.   GASTROENTEROLOGY

Cancer Epigenetics: A Brief Review

(2013) S. Virani et al.   ILAR JOURNAL

Promoter methylation of DAPK1, FHIT, MGMT, and CDKN2A genes in cervical carcinoma

(2013) Chiaki Banzai et al.   International Journal of Clinical Oncology

DNMT3B7 expression related to MENT expression and its promoter methylation in human lymphomas

(2013) Lobna Alkebsi et al.   LEUKEMIA RESEARCH

GCPII modulates oxidative stress and prostate cancer susceptibility through changes in methylation of RASSF1, BNIP3, GSTP1 and Ec-SOD

(2013) Shree Divyya et al.   MOLECULAR BIOLOGY REPORTS

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

(2013) Christopher J. Millard et al.   MOLECULAR CELL

Promoter hypermethylation of the tumor-suppressor genes RASSF1A, GSTP1 and CDH1 in endometrial cancer

(2013) ROMAN FIOLKA et al.   ONCOLOGY REPORTS

Downregulation of IFNG in CD4+ T Cells in Lung Cancer through Hypermethylation: A Possible Mechanism of Tumor-Induced Immunosuppression

(2013) Fang Wang et al.   PLoS One

Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management

(2013) Timothy Chan et al.   OncoTargets and Therapy

HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses

(2013) J E Bolden et al.   Cell Death & Disease

Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

(2012) Jueng Soo You et al.   CANCER CELL

Sulforaphane causes a major epigenetic repression of myostatin in porcine satellite cells

(2012) Huitao Fan et al.   Epigenetics

ZINC: A Free Tool to Discover Chemistry for Biology

(2012) John J. Irwin et al.   Journal of Chemical Information and Modeling

Inhibition of epstein-barr virus reactivation in nasopharyngeal carcinoma cells by dietary sulforaphane

(2012) Chung-Chun Wu et al.   MOLECULAR CARCINOGENESIS

5-Aza-2′-deoxycytidine Leads to Reduced Embryo Implantation and Reduced Expression of DNA Methyltransferases and Essential Endometrial Genes

(2012) Yu-Bin Ding et al.   PLoS One

Molecular Modeling Study on Tunnel Behavior in Different Histone Deacetylase Isoforms

(2012) Sundarapandian Thangapandian et al.   PLoS One

Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect

(2011) Fulvia Zanichelli et al.   AGE

Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide

(2011) J Chang et al.   BRITISH JOURNAL OF CANCER

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

(2011) John D. Clarke et al.   MOLECULAR NUTRITION & FOOD RESEARCH

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Association of aberrant DNA methylation with clinicopathological features in breast cancer

(2011) Aggeliki Tserga   ONCOLOGY REPORTS

Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells

(2011) Anna Hsu et al.   Clinical Epigenetics

Overexpression of DNA Methyltransferases 1, 3a, and 3b Significantly Correlates With Retinoblastoma Tumorigenesis

(2010) Yi Qu et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Toward the estimation of the absolute quality of individual protein structure models

(2010) Pascal Benkert et al.   BIOINFORMATICS

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

(2010) Jerome C. Bressi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anti-carcinogenic effects of sulforaphane in association with its apoptosis-inducing and anti-inflammatory properties in human cervical cancer cells

(2010) Chhavi Sharma et al.   Cancer Epidemiology

Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

(2010) D. Kuck et al.   MOLECULAR CANCER THERAPEUTICS

Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme

(2010) Katan Patel et al.   NUCLEIC ACIDS RESEARCH

Histone Deacetylation

(2008) Anas Al-Janadi et al.   Drugs in research & development

Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs)

(2007) Stefan Schäfer et al.   BIOORGANIC & MEDICINAL CHEMISTRY