Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells

Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway

(2015) Tien-Hui Lu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Lotus Leaf (Nelumbo nucifera) and its Active Constituents Prevent Inflammatory Responses in Macrophages via JNK/NF-κB Signaling Pathway

(2014) Shing-Hwa Liu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Glucopsychosine increases cytosolic calcium to induce calpain-mediated apoptosis of acute myeloid leukemia cells

(2014) Leonard Angka et al.   CANCER LETTERS

Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction

(2014) M Chen et al.   CELL DEATH AND DIFFERENTIATION

ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin

(2014) Julia Leitman et al.   PLoS One

Sialic Acid Rescues Repurified Lipopolysaccharide-Induced Acute Renal Failure via Inhibiting TLR4/PKC/gp91-Mediated Endoplasmic Reticulum Stress, Apoptosis, Autophagy, and Pyroptosis Signaling

(2014) Chih-Ching Yang et al.   TOXICOLOGICAL SCIENCES

PUMA mediates ER stress-induced apoptosis in portal hypertensive gastropathy

(2014) S Tan et al.   Cell Death & Disease

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells

(2014) Y Teng et al.   Cell Death & Disease

Glucose deprivation induces reticulum stress by the PERK pathway and caspase-7- and calpain-mediated caspase-12 activation

(2013) Selene García de la Cadena et al.   APOPTOSIS

Zinc and Copper Levels in Bladder Cancer: A Systematic Review and Meta-Analysis

(2013) Song Mao et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters

(2013) Joo Ae Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways

(2013) Tien-Hui Lu et al.   TOXICOLOGY LETTERS

PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts

(2013) A Bluwstein et al.   Cell Death & Disease

Role of protein kinase C δ in ER stress and apoptosis induced by oxidized LDL in human vascular smooth muscle cells

(2013) P Larroque-Cardoso et al.   Cell Death & Disease

Ursolic acid induces ER stress response to activate ASK1–JNK signaling and induce apoptosis in human bladder cancer T24 cells

(2012) Qing-you Zheng et al.   CELLULAR SIGNALLING

Implication of eIF2α kinase GCN2 in induction of apoptosis and endoplasmic reticulum stress-responsive genes by sodium salicylate

(2012) Solange H.L. Gentz et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Bufalin induces G0/G1 phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells

(2012) Wen-Wen Huang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals

(2012) Chun-Hung Chen et al.   TOXICOLOGY

PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway

(2011) Wei Li et al.   CANCER LETTERS

Extract of Lotus Leaf (Nelumbo nucifera) and Its Active Constituent Catechin with Insulin Secretagogue Activity

(2011) Chun Fa Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

SnapShot: The Unfolded Protein Response

(2010) R. Luke Wiseman et al.   CELL

Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer

(2010) Ssu-Ming Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

(2009) Ying-Ju Chen et al.   CANCER LETTERS

Inhibition of eIF2α Dephosphorylation Maximizes Bortezomib Efficiency and Eliminates Quiescent Multiple Myeloma Cells Surviving Proteasome Inhibitor Therapy

(2009) Denis M. Schewe et al.   CANCER RESEARCH

Synergistic Apoptosis Induction in Leukemic Cells by the Phosphatase Inhibitor Salubrinal and Proteasome Inhibitors

(2009) Hannes C. A. Drexler   PLoS One

Cantharidin induces apoptosis of human multiple myeloma cells via inhibition of the JAK/STAT pathway

(2008) Morihiko Sagawa et al.   CANCER SCIENCE

The PKC  -Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis

(2008) X. Qi et al.   JOURNAL OF CELL SCIENCE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE