Tanshinone IIA Prevents Leu27IGF-II-Induced Cardiomyocyte Hypertrophy Mediated by Estrogen Receptor and Subsequent Akt Activation

Citrus medica var. sarcodactylis (Foshou) Activates Fibroblast Growth Factor-2 Signaling to Induce Migration of RSC96 Schwann Cells

(2014) Chih-Yang Huang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Novel Target Genes Responsive to Apoptotic Activity by Ocimum gratissimum in Human Osteosarcoma Cells

(2014) Chien-Chung Lin et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Dilong Prevents the High-KCl Cardioplegic Solution Administration-Induced Apoptosis in H9c2 Cardiomyoblast Cells Mediated by MEK

(2014) Chien-Kuo Han et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Genistein Suppresses the Isoproterenol-Treated H9c2 Cardiomyoblast Cell Apoptosis Associated with P-38, Erk1/2, JNK, and NFκB Signaling Protein Activation

(2013) Wei-Syun Hu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Effects of Tetramethylpyrazine on Microglia Activation in Spinal Cord Compression Injury of Mice

(2013) Jung-Won Shin et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Salvia miltiorrhiza (Dan Shen) Significantly Ameliorates Colon Inflammation in Dextran Sulfate Sodium Induced Colitis

(2013) Xiao-Dong Wen et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Regulation of antioxidant system, lipids and fatty acid β-oxidation contributes to the cardioprotective effect of sodium tanshinone IIA sulphonate in isoproterenol-induced myocardial infarction in rats

(2013) Bo Wei et al.   ATHEROSCLEROSIS

Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts

(2013) Yueh-Shan Weng et al.   FOOD AND CHEMICAL TOXICOLOGY

Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways

(2013) Caiyu Lin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TanshinoneIIA and Cryptotanshinone Protect against Hypoxia-Induced Mitochondrial Apoptosis in H9c2 Cells

(2013) Hyou-Ju Jin et al.   PLoS One

Tanshinone IIA Improves miR-133 Expression Through MAPK ERK1/2 Pathway in Hypoxic Cardiac Myocytes

(2012) Li Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cardiovascular actions and therapeutic potential of tanshinone IIA

(2011) Si Gao et al.   ATHEROSCLEROSIS

Direct Vasorelaxation by a Novel Phytoestrogen Tanshinone IIA Is Mediated by Nongenomic Action of Estrogen Receptor Through Endothelial Nitric Oxide Synthase Activation and Calcium Mobilization

(2011) Guanwei Fan et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Histone acetylation is essential for ANG-II-induced IGF-IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart

(2011) Chun-Hsien Chu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes

(2010) Agnieszka Biala et al.   BLOOD PRESSURE

Tanshinone IIA attenuates atherosclerosis in ApoE−/− mice through down-regulation of scavenger receptor expression

(2010) Fu-Tian Tang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Akt mediates 17β-estradiol and/or estrogen receptor-α inhibition of LPS-induced tumor necresis factor-α expression and myocardial cell apoptosis by suppressing the JNK1/2-NFκB pathway

(2010) Chung-Jung Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Systolic heart failure: Chronic and acute syndromes

(2009) Kanu Chatterjee et al.   CRITICAL CARE MEDICINE

Tanshinone IIA pretreatment protects myocardium against ischaemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway in diabetic rats

(2009) Y. Zhang et al.   DIABETES OBESITY & METABOLISM

Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer

(2009) Lu   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS

(2009) Guan-Wei Fan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in Myocardial Cells

(2008) Chun-Hsien Chu et al.   ENDOCRINOLOGY

Tanshinone IIA: A new activator of human cardiac KCNQ1/KCNE1 (IKs) potassium channels

(2008) Dong-Dong Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Correlation ofSalvia miltiorrhizaExtract–Induced Regulation of Osteoclastogenesis with the Amount of Components Tanshinone I, Tanshinone IIA, Cryptotanshinone, and Dihydrotanshinone

(2008) Hae-Kyung Kim et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen)

(2008) Yong-Guo Li et al.   JOURNAL OF CHROMATOGRAPHY A

IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Gαq interaction and protein kinase C-α/CaMKII activation in H9c2 cardiomyoblast cells

(2008) Chun-Hsien Chu et al.   JOURNAL OF ENDOCRINOLOGY

IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells

(2008) Mu-Hsin Chang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY