Targeting Ongoing DNA Damage in Multiple Myeloma: Effects of DNA Damage Response Inhibitors on Plasma Cell Survival
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Title
Targeting Ongoing DNA Damage in Multiple Myeloma: Effects of DNA Damage Response Inhibitors on Plasma Cell Survival
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-05-19
DOI
10.3389/fonc.2017.00098
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- (2015) María-Victoria Mateos et al. BLOOD REVIEWS
- Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
- (2015) A. Bakr et al. NUCLEIC ACIDS RESEARCH
- Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma
- (2015) F. Cottini et al. Cancer Discovery
- Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability
- (2015) Ana B. Herrero et al. PLoS One
- Targeting DNA damage response in cancer therapy
- (2014) Noriko Hosoya et al. CANCER SCIENCE
- DNA replication stress: Causes, resolution and disease
- (2014) Abdelghani Mazouzi et al. EXPERIMENTAL CELL RESEARCH
- A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin
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- Molecular pathogenesis of multiple myeloma: basic and clinical updates
- (2013) Marta Chesi et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma
- (2012) P. L. Bergsagel et al. BLOOD
- The Checkpoint Kinase Inhibitor AZD7762 Potentiates Chemotherapy-Induced Apoptosis of p53-Mutated Multiple Myeloma Cells
- (2012) H. J. Landau et al. MOLECULAR CANCER THERAPEUTICS
- Activation of DSB Processing Requires Phosphorylation of CtIP by ATR
- (2012) Shaun E. Peterson et al. MOLECULAR CELL
- Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening
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- Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX
- (2011) D K Walters et al. LEUKEMIA
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- Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
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- Anticancer therapy with checkpoint inhibitors: what, where and when?
- (2011) Michelle D. Garrett et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax
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