Intra- and Intercellular Quality Control Mechanisms of Mitochondria

Drp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals

(2017) Chenxia Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

(2017) Inés Sáenz-de-Santa-María et al.   Oncotarget

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

(2017) Rong Yu et al.   Scientific Reports

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins

(2017) Vladimir V. Rogov et al.   Scientific Reports

Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription

(2016) Viktor Posse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

(2016) Gian-Luca McLelland et al.   JOURNAL OF CELL BIOLOGY

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

(2016) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Autophagy core machinery: overcoming spatial barriers in neurons

(2016) Aileen R. Ariosa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation

(2016) Aparna Ramachandran et al.   NUCLEIC ACIDS RESEARCH

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

(2016) I. Ku hl et al.   Science Advances

Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease

(2015) Janice M. Huss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

(2015) X Wang et al.   CELL DEATH AND DIFFERENTIATION

PPARs and ERRs: molecular mediators of mitochondrial metabolism

(2015) Weiwei Fan et al.   CURRENT OPINION IN CELL BIOLOGY

(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation

(2015) F. C. Fiesel et al.   EMBO REPORTS

New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond

(2015) Josep A. Villena   FEBS Journal

The Function of Autophagy in Neurodegenerative Diseases

(2015) Yoshimitsu Kiriyama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

(2015) Jin-Mi Heo et al.   MOLECULAR CELL

Mechanism of phospho-ubiquitin-induced PARKIN activation

(2015) Tobias Wauer et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

(2015) Donald G. Phinney et al.   Nature Communications

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

(2014) Agne Kazlauskaite et al.   BIOCHEMICAL JOURNAL

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy

(2014) Tanveer Ahmad et al.   EMBO JOURNAL

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

(2014) Gian-Luca McLelland et al.   EMBO JOURNAL

Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

(2014) Ruchika Anand et al.   JOURNAL OF CELL BIOLOGY

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

(2014) Guo Chen et al.   MOLECULAR CELL

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

A novel intermediate in transcription initiation by human mitochondrial RNA polymerase

(2014) Yaroslav I. Morozov et al.   NUCLEIC ACIDS RESEARCH

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

(2014) Huu B. Ngo et al.   Nature Communications

The reciprocal roles of PARK2 and mitofusins in mitophagy and mitochondrial spheroid formation

(2013) Xiao-Ming Yin et al.   Autophagy

PINK1 is degraded through the N-end rule pathway

(2013) Koji Yamano et al.   Autophagy

The LC3 interactome at a glance

(2013) P. Wild et al.   JOURNAL OF CELL SCIENCE

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival MitophagyversusApoptosis

(2012) Yanyan Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin and Mitofusins Reciprocally Regulate Mitophagy and Mitochondrial Spheroid Formation

(2012) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Microscopic Analysis of a Spherical Mitochondrial Structure

(2012) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

(2012) Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of Bcl-2 homology motifs: homology versus homoplasy

(2012) Abdel Aouacheria et al.   TRENDS IN CELL BIOLOGY

Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes

(2011) Kangmin He et al.   CARDIOVASCULAR RESEARCH

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

(2011) Jian Zhao et al.   EMBO JOURNAL

MiD49 and MiD51, new components of the mitochondrial fission machinery

(2011) Catherine S Palmer et al.   EMBO REPORTS

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

(2011) Cathrin Meissner et al.   JOURNAL OF NEUROCHEMISTRY

Adriamycin Nephropathy

(2010) Kaoru Yasuda et al.   AMERICAN JOURNAL OF PATHOLOGY

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

(2010) Melissa N. Quinsay et al.   Autophagy

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome

(2009) Metodi D. Metodiev et al.   Cell Metabolism

The Miro GTPases: At the heart of the mitochondrial transport machinery

(2009) Katarina Reis et al.   FEBS LETTERS

Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1

(2009) Sarah Ehses et al.   JOURNAL OF CELL BIOLOGY

How peroxisomes multiply

(2009) E. H. Hettema et al.   JOURNAL OF CELL SCIENCE

PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression

(2008) Kristel Vercauteren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS