Enhanced neuroinvasion by smaller, soluble prions

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation

(2016) Sara Breid et al.   JOURNAL OF VIROLOGY

Protein aggregates stimulate macropinocytosis facilitating their propagation

(2016) Justin J. Yerbury   Prion

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

(2016) Xiaobei Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

(2016) James A. Carroll et al.   PLoS Pathogens

SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

(2015) Rafaa Zeineddine et al.   Molecular Neurodegeneration

A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP

(2015) April M. Weissmiller et al.   PLoS One

Structure-based drug design identifies polythiophenes as antiprion compounds

(2015) Uli S. Herrmann et al.   Science Translational Medicine

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

(2014) Xiaobei Zhao et al.   Jove-Journal of Visualized Experiments

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

(2013) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

(2013) O. N. Gill et al.   BMJ-British Medical Journal

Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates

(2012) Ilan Margalith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion propagation, toxicity and degradation

(2012) Adriano Aguzzi et al.   NATURE NEUROSCIENCE

Biochemical Properties of Highly Neuroinvasive Prion Strains

(2012) Cyrus Bett et al.   PLoS Pathogens

Aerosols Transmit Prions to Immunocompetent and Immunodeficient Mice

(2011) Johannes Haybaeck et al.   PLoS Pathogens

Crucial Role for Prion Protein Membrane Anchoring in the Neuroinvasion and Neural Spread of Prion Infection

(2010) M. Klingeborn et al.   JOURNAL OF VIROLOGY

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

(2010) Jason M. Wilham et al.   PLoS Pathogens

The Physical Relationship between Infectivity and Prion Protein Aggregates Is Strain-Dependent

(2010) Philippe Tixador et al.   PLoS Pathogens

Role of the Lymphoreticular System in Prion Neuroinvasion from the Oral and Nasal Mucosa

(2009) R. A. Bessen et al.   JOURNAL OF VIROLOGY

Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils

(2009) E. Chatani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of cerebral  -amyloidosis: Intracerebral versus systemic A  inoculation

(2009) Y. S. Eisele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of prion protein proteolysis and disaggregation on the strain properties of hamster scrapie

(2008) A. M. Deleault et al.   JOURNAL OF GENERAL VIROLOGY

Conformational Stability of PrP Amyloid Fibrils Controls Their Smallest Possible Fragment Size

(2008) Ying Sun et al.   JOURNAL OF MOLECULAR BIOLOGY

Prominent and Persistent Extraneural Infection in Human PrP Transgenic Mice Infected with Variant CJD

(2008) Vincent Béringue et al.   PLoS One

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

(2008) Magdalini Polymenidou et al.   PLoS One

Intraspecies Transmission of BASE Induces Clinical Dullness and Amyotrophic Changes

(2008) Guerino Lombardi et al.   PLoS Pathogens