Use of the Ketogenic Diet to Treat Intractable Epilepsy in Mitochondrial Disorders

Low glycemic index treatment for seizure control in Angelman syndrome: A case series from the Center for Dietary Therapy of Epilepsy at the Massachusetts General Hospital

(2017) Olivia R. Grocott et al.   EPILEPSY & BEHAVIOR

Control of seizures by ketogenic diet-induced modulation of metabolic pathways

(2016) Ryan M. Clanton et al.   AMINO ACIDS

Mitochondrial cytopathies

(2016) Ayman W. El-Hattab et al.   CELL CALCIUM

Ketogenic diet effects on neurobehavioral development of children with intractable epilepsy: A prospective study

(2016) Dengna Zhu et al.   EPILEPSY & BEHAVIOR

Ketogenic diets: from cancer to mitochondrial diseases and beyond

(2016) Ana F. Branco et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Ketogenic diet guidelines for infants with refractory epilepsy

(2016) Elles van der Louw et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model

(2016) Stephanie L. Ciarlone et al.   NEUROBIOLOGY OF DISEASE

Epilepsy in adults with mitochondrial disease: A cohort study

(2015) Roger G. Whittaker et al.   ANNALS OF NEUROLOGY

Seizure control by decanoic acid through direct AMPA receptor inhibition

(2015) Pishan Chang et al.   BRAIN

Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure

(2015) Andrea Viggiano et al.   BRAIN RESEARCH

Antioxidants as a Preventive Treatment for Epileptic Process: A Review of the Current Status

(2015) Bostjan Martinc et al.   Current Neuropharmacology

Mitochondria: The ketogenic diet—A metabolism-based therapy

(2015) Silvia Vidali et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial disease: genetics and management

(2015) Yi Shiau Ng et al.   JOURNAL OF NEUROLOGY

Acute anticonvulsant effects of capric acid in seizure tests in mice

(2015) Piotr Wlaź et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Targeting LDH enzymes with a stiripentol analog to treat epilepsy

(2015) N. Sada et al.   SCIENCE

The Role of Reactive Species in Epileptogenesis and Influence of Antiepileptic Drug Therapy on Oxidative Stress

(2015) Bostjan Martinc et al.   Current Neuropharmacology

Ketones Prevent Oxidative Impairment of Hippocampal Synaptic Integrity through KATP Channels

(2015) Do Young Kim et al.   PLoS One

Ketogenic Diet

(2014) Radhika Dhamija et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Seizure semiology and EEG findings in mitochondrial diseases

(2014) Justyna A. Chevallier et al.   EPILEPSIA

Ketogenic diets, mitochondria, and neurological diseases

(2014) Lindsey B. Gano et al.   JOURNAL OF LIPID RESEARCH

The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells

(2014) Sean David Hughes et al.   JOURNAL OF NEUROCHEMISTRY

A decade of the modified Atkins diet (2003–2013): Results, insights, and future directions

(2013) Eric H. Kossoff et al.   EPILEPSY & BEHAVIOR

Mitochondrial involvement and oxidative stress in temporal lobe epilepsy

(2013) Shane Rowley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ketogenic diets

(2012) Eric H. Kossoff et al.   CURRENT OPINION IN NEUROLOGY

Mitochondrial diseases and epilepsy

(2012) Laurence A. Bindoff et al.   EPILEPSIA

Prolonged seizure activity impairs mitochondrial bioenergetics and induces cell death

(2012) S. Kovac et al.   JOURNAL OF CELL SCIENCE

Ketone bodies in epilepsy

(2012) Melanie A. McNally et al.   JOURNAL OF NEUROCHEMISTRY

Seizure control by ketogenic diet-associated medium chain fatty acids

(2012) Pishan Chang et al.   NEUROPHARMACOLOGY

Epilepsy in mitochondrial disorders

(2012) Josef Finsterer et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Mitochondrial toxicity of antiepileptic drugs and their tolerability in mitochondrial disorders

(2011) Josef Finsterer et al.   Expert Opinion on Drug Metabolism & Toxicology

The ketogenic diet in childhood epilepsy: where are we now?

(2010) J. H. Cross et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Epileptic phenotypes in children with respiratory chain disorders

(2010) Sandra El Sabbagh et al.   EPILEPSIA

Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy?

(2010) Simon Waldbaum et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Metabolic Control of Vesicular Glutamate Transport and Release

(2010) Narinobu Juge et al.   NEURON

Dietary therapies – an old idea with a new lease of life

(2010) J. Helen Cross   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Long-term outcome and tolerability of the ketogenic diet in drug-resistant childhood epilepsy—The Austrian experience

(2010) Anastasia Dressler et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

A case of Ohtahara syndrome with mitochondrial respiratory chain complex I deficiency

(2009) Joo Hee Seo et al.   BRAIN & DEVELOPMENT

The ketogenic diet and epilepsy

(2009) Do Young Kim et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis

(2009) CHRISTINE BARNERIAS et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Efficacy, safety, and tolerability of the low glycemic index treatment in pediatric epilepsy

(2009) David A. Muzykewicz et al.   EPILEPSIA

The ketogenic diet: Uses in epilepsy and other neurologic illnesses

(2008) Kristin W. Barañano et al.   Current Treatment Options in Neurology

The Modified Atkins Diet

(2008) Eric H. Kossoff et al.   EPILEPSIA

Mitochondrial respiratory chain defects: Underlying etiology in various epileptic conditions

(2008) Young Mock Lee et al.   EPILEPSIA

A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy

(2008) Elizabeth G. Neal et al.   EPILEPSIA

The ketogenic diet increases mitochondrial glutathione levels

(2008) Stuart G. Jarrett et al.   JOURNAL OF NEUROCHEMISTRY

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

Prevalence of mitochondrial DNA disease in adults

(2007) Andrew M. Schaefer et al.   ANNALS OF NEUROLOGY