Theory, simulations and the design of functionalized nanoparticles for biomedical applications: A Soft Matter Perspective

Sorption and Spatial Distribution of Protein Globules in Charged Hydrogel Particles

(2017) Irene Adroher-Benítez et al.   LANGMUIR

Kinetics of receptor-mediated endocytosis of elastic nanoparticles

(2017) Xin Yi et al.   Nanoscale

Exploiting Receptor Competition to Enhance Nanoparticle Binding Selectivity

(2017) Stefano Angioletti-Uberti   PHYSICAL REVIEW LETTERS

Optimal multivalent targeting of membranes with many distinct receptors

(2017) Tine Curk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clathrate colloidal crystals

(2017) Haixin Lin et al.   SCIENCE

A Simple Model of Multivalent Adhesion and Its Application to Influenza Infection

(2016) Huafeng Xu et al.   BIOPHYSICAL JOURNAL

Communication: Simple approach for calculating the binding free energy of a multivalent particle

(2016) Nicholas B. Tito et al.   JOURNAL OF CHEMICAL PHYSICS

Communication: Free energy of ligand-receptor systems forming multimeric complexes

(2016) Lorenzo Di Michele et al.   JOURNAL OF CHEMICAL PHYSICS

Incorporation of Soft Particles into Lipid Vesicles: Effects of Particle Size and Elasticity

(2016) Xin Yi et al.   LANGMUIR

Broadly Accessible Self-Consistent Field Theory for Block Polymer Materials Discovery

(2016) Akash Arora et al.   MACROMOLECULES

Theory and simulation of DNA-coated colloids: a guide for rational design

(2016) Stefano Angioletti-Uberti et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Rational design of molecularly imprinted polymers

(2016) Tine Curk et al.   Soft Matter

Simulation and Theory of Antibody Binding to Crowded Antigen-Covered Surfaces

(2016) Cristiano De Michele et al.   PLoS Computational Biology

Surface tension and Laplace pressure in triangulated surface models for membranes without fixed boundary

(2015) Hiroshi Koibuchi et al.   JOURNAL OF MATHEMATICAL CHEMISTRY

Competitive Protein Adsorption to Soft Polymeric Layers: Binary Mixtures and Comparison to Theory

(2015) Michael Oberle et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Nanoparticle hardness controls the internalization pathway for drug delivery

(2015) Ye Li et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection

(2015) Antonio Muñoz et al.   Nature Chemistry

Liquid-crystalline ordering of antimicrobial peptide–DNA complexes controls TLR9 activation

(2015) Nathan W. Schmidt et al.   NATURE MATERIALS

Designing multivalent probes for tunable superselective targeting

(2015) Galina V. Dubacheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of ligand distribution on uptake efficiency

(2015) Veronika Schubertová et al.   Soft Matter

Endocytosis of PEGylated nanoparticles accompanied by structural and free energy changes of the grafted polyethylene glycol

(2014) Ying Li et al.   BIOMATERIALS

Superselective Targeting Using Multivalent Polymers

(2014) Galina V. Dubacheva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shape and Orientation Matter for the Cellular Uptake of Nonspherical Particles

(2014) Sabyasachi Dasgupta et al.   NANO LETTERS

Mobile Linkers on DNA-Coated Colloids: Valency without Patches

(2014) Stefano Angioletti-Uberti et al.   PHYSICAL REVIEW LETTERS

Dynamic density functional theory of protein adsorption on polymer-coated nanoparticles

(2014) Stefano Angioletti-Uberti et al.   Soft Matter

Engineered nanoparticles interacting with cells: size matters

(2014) Li Shang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Communication: A simple analytical formula for the free energy of ligand–receptor-mediated interactions

(2013) Stefano Angioletti-Uberti et al.   JOURNAL OF CHEMICAL PHYSICS

Role of Nanoparticle Geometry in Endocytosis: Laying Down to Stand Up

(2013) Changjin Huang et al.   NANO LETTERS

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Adsorption of proteins to functional polymeric nanoparticles

(2013) Nicole Welsch et al.   POLYMER

Wrapping of ellipsoidal nano-particles by fluid membranes

(2013) Sabyasachi Dasgupta et al.   Soft Matter

Permission to Enter Cell by Shape: Nanodisk vs Nanosphere

(2012) Yi Zhang et al.   ACS Applied Materials & Interfaces

Intracellular Release of Endocytosed Nanoparticles Upon a Change of Ligand–Receptor Interaction

(2012) Robert Vácha et al.   ACS Nano

Cooperative Effect in Receptor-Mediated Endocytosis of Multiple Nanoparticles

(2012) Tongtao Yue et al.   ACS Nano

Designing Nanoparticle Translocation through Membranes by Computer Simulations

(2012) Hong-ming Ding et al.   ACS Nano

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Role of physicochemical properties of coating ligands in receptor-mediated endocytosis of nanoparticles

(2012) Hong-ming Ding et al.   BIOMATERIALS

Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics

(2012) Ye Li et al.   BIOMATERIALS

A general theory of DNA-mediated and other valence-limited colloidal interactions

(2012) Patrick Varilly et al.   JOURNAL OF CHEMICAL PHYSICS

Protein Sorption to Charged Microgels: Characterizing Binding Isotherms and Driving Forces

(2012) Cemil Yigit et al.   LANGMUIR

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Controlling the Folding and Substrate-Binding of Proteins Using Polymer Brushes

(2012) Brenda M. Rubenstein et al.   PHYSICAL REVIEW LETTERS

Quantitative Prediction of the Phase Diagram of DNA-Functionalized Nanosized Colloids

(2012) Bianca M. Mladek et al.   PHYSICAL REVIEW LETTERS

How Shape Influences Uptake: Interactions of Anisotropic Polymer Nanoparticles and Human Mesenchymal Stem Cells

(2012) Laura Florez et al.   Small

Protein binding to soft polymeric layers: a quantitative study by fluorescence spectroscopy

(2012) Nicole Welsch et al.   Soft Matter

Virus Capsid Dissolution Studied by Microsecond Molecular Dynamics Simulations

(2012) Daniel S. D. Larsson et al.   PLoS Computational Biology

Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise

(2011) Ernst Wagner   ACCOUNTS OF CHEMICAL RESEARCH

Coarse-Grained Simulations of Macromolecules: From DNA to Nanocomposites

(2011) Juan J. de Pablo   Annual Review of Physical Chemistry

Inhibition of Influenza Virus Activity by Multivalent Glycoarchitectures with Matched Sizes

(2011) Ilona Papp et al.   CHEMBIOCHEM

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collapse of Thermoresponsive Brushes and the Tuning of Protein Adsorption

(2011) A. Halperin et al.   MACROMOLECULES

Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes

(2011) Robert Vácha et al.   NANO LETTERS

Dynamics and Statics of DNA-Programmable Nanoparticle Self-Assembly and Crystallization

(2011) C. Knorowski et al.   PHYSICAL REVIEW LETTERS

Cellular Uptake of Elastic Nanoparticles

(2011) Xin Yi et al.   PHYSICAL REVIEW LETTERS

Design Rule for Colloidal Crystals of DNA-Functionalized Particles

(2011) Francisco J. Martinez-Veracoechea et al.   PHYSICAL REVIEW LETTERS

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designing super selectivity in multivalent nano-particle binding

(2011) F. J. Martinez-Veracoechea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core–shell microgels as “smart” carriers for enzymes

(2011) Nicole Welsch et al.   Soft Matter

Interaction between lysozyme and colloidal poly(NIPAM-co-acrylic acid) microgels

(2010) Christian Johansson et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Observation of empty liquids and equilibrium gels in a colloidal clay

(2010) Barbara Ruzicka et al.   NATURE MATERIALS

One-particle-thick, solvent-free, coarse-grained model for biological and biomimetic fluid membranes

(2010) Hongyan Yuan et al.   PHYSICAL REVIEW E

Variable Nanoparticle-Cell Adhesion Strength Regulates Cellular Uptake

(2010) Hongyan Yuan et al.   PHYSICAL REVIEW LETTERS

Inhibition of HSV-1 Attachment, Entry, and Cell-to-Cell Spread by Functionalized Multivalent Gold Nanoparticles

(2010) Dana Baram-Pinto et al.   Small

Anomalous phase behavior of liquid–vapor phase transition in binary mixtures of DNA-coated particles

(2010) Francisco J. Martinez-Veracoechea et al.   Soft Matter

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

Polymersomes: nature inspired nanometer sized compartments

(2009) Caterina LoPresti et al.   JOURNAL OF MATERIALS CHEMISTRY

Membrane Simulation Models from Nanometer to Micrometer Scale

(2009) Hiroshi Noguchi   JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN

Ternary Protein Adsorption onto Brushes: Strong versus Weak

(2009) A. Halperin et al.   LANGMUIR

Enzyme-Responsive Nanoparticle Systems

(2008) James E. Ghadiali et al.   ADVANCED MATERIALS

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Adsorption of the Protein Bovine Serum Albumin in a Planar Poly(acrylic acid) Brush Layer As Measured by Optical Reflectometry

(2008) Wiebe M. de Vos et al.   LANGMUIR

Beyond drug delivery

(2008) Mauro Ferrari   Nature Nanotechnology

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiscale Simulation of Soft Matter: From Scale Bridging to Adaptive Resolution

(2007) Matej Praprotnik et al.   Annual Review of Physical Chemistry

Design maps for nanoparticles targeting the diseased microvasculature

(2007) Paolo Decuzzi et al.   BIOMATERIALS