A murine preclinical syngeneic transplantation model for breast cancer precision medicine

PARP inhibitors: the race is on

(2016) Jessica S Brown et al.   BRITISH JOURNAL OF CANCER

Metaplastic Carcinoma of the Breast

(2015) Elizabeth McKinnon et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

(2015) Georgina V Long et al.   LANCET

Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models

(2015) Antonina Mitrofanova et al.   Cell Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Cross-Species Regulatory Network Analysis Identifies a Synergistic Interaction between FOXM1 and CENPF that Drives Prostate Cancer Malignancy

(2014) Alvaro Aytes et al.   CANCER CELL

New Strategies for Triple-Negative Breast Cancer--Deciphering the Heterogeneity

(2014) I. A. Mayer et al.   CLINICAL CANCER RESEARCH

Luminal B Breast Cancer: Molecular Characterization, Clinical Management, and Future Perspectives

(2014) Felipe Ades et al.   JOURNAL OF CLINICAL ONCOLOGY

LPA receptor signaling: pharmacology, physiology, and pathophysiology

(2014) Yun C. Yung et al.   JOURNAL OF LIPID RESEARCH

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease

(2014) Janan T. Eppig et al.   NUCLEIC ACIDS RESEARCH

Genome-wide transcriptome profiling of homologous recombination DNA repair

(2014) Guang Peng et al.   Nature Communications

Genetic heterogeneity in breast cancer: the road to personalized medicine?

(2013) Richard D Baird et al.   BMC Medicine

Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice

(2013) J. Usary et al.   CLINICAL CANCER RESEARCH

Lactate Dehydrogenase B: A Metabolic Marker of Response to Neoadjuvant Chemotherapy in Breast Cancer

(2013) J. B. Dennison et al.   CLINICAL CANCER RESEARCH

Proteomic Markers of DNA Repair and PI3K Pathway Activation Predict Response to the PARP Inhibitor BMN 673 in Small Cell Lung Cancer

(2013) R. J. Cardnell et al.   CLINICAL CANCER RESEARCH

Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

(2013) J. Murai et al.   MOLECULAR CANCER THERAPEUTICS

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

(2013) Adam D Pfefferle et al.   GENOME BIOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Resistance to PARP-Inhibitors in Cancer Therapy

(2013) Alicia Montoni et al.   Frontiers in Pharmacology

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

(2012) A. Kreso et al.   SCIENCE

Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

(2012) Lauren Averett Byers et al.   Cancer Discovery

Synthetic lethality: exploiting the addiction of cancer to DNA repair

(2011) M. Shaheen et al.   BLOOD

Heterogeneity of breast cancer: etiology and clinical relevance

(2011) Vanessa Almendro et al.   Clinical & Translational Oncology

Basal Breast Cancer: A Complex and Deadly Molecular Subtype

(2011) F. Bertucci et al.   CURRENT MOLECULAR MEDICINE

Insights into autotaxin: how to produce and present a lipid mediator

(2011) Wouter H. Moolenaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATX-LPA receptor axis in inflammation and cancer

(2010) Shuying Liu et al.   CELL CYCLE

Functional Proteomic Analysis of Advanced Serous Ovarian Cancer Using Reverse Phase Protein Array: TGF-  Pathway Signaling Indicates Response to Primary Chemotherapy

(2010) M. S. Carey et al.   CLINICAL CANCER RESEARCH

Deconstructing the molecular portraits of breast cancer

(2010) Aleix Prat et al.   Molecular Oncology

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

(2009) Shuying Liu et al.   CANCER CELL

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY