The Eight and a Half Year Journey of Undiagnosed AD: Gene Sequencing and Funding of Advanced Genetic Testing Has Led to Hope and New Beginnings

Additional data on the clinical phenotype of Helsmoortel-Van der Aa syndrome associated with a novel truncating mutation inADNPgene

(2016) Małgorzata Krajewska-Walasek et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Facing the times: A young onset dementia support group: FacebookTMstyle

(2016) Denise Craig et al.   AUSTRALASIAN JOURNAL ON AGEING

D-SAL and NAP: Two Peptides Sharing a SIP Domain

(2016) Illana Gozes et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Comprehensive molecular testing in patients with high functioning autism spectrum disorder

(2016) Maria Isabel Alvarez-Mora et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A systematic variant annotation approach for ranking genes associated with autism spectrum disorders

(2016) Eric Larsen et al.   Molecular Autism

The Compassionate Side of Neuroscience: Tony Sermone’s Undiagnosed Genetic Journey—ADNP Mutation

(2015) Illana Gozes et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms

(2015) Alissa M. D’Gama et al.   NEURON

Low load for disruptive mutations in autism genes and their biased transmission

(2015) Ivan Iossifov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model

(2015) Sinaya Vaisburd et al.   Scientific Reports

Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer’s pathologies

(2015) A Malishkevich et al.   Translational Psychiatry

The transcriptional regulatorADNPlinks the BAF (SWI/SNF) complexes with autism

(2014) Geert Vandeweyer et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

New horizons in schizophrenia treatment: autophagy protection is coupled with behavioral improvements in a mouse model of schizophrenia

(2014) Avia Merenlender-Wagner et al.   Autophagy

Expansion of the clinical phenotype associated with mutations inactivity-dependent neuroprotective protein

(2014) Matthew F Pescosolido et al.   JOURNAL OF MEDICAL GENETICS

The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins

(2014) S Oz et al.   MOLECULAR PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Large-scale discovery of novel genetic causes of developmental disorders

(2014) T. W. Fitzgerald et al.   NATURE

A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP

(2014) Céline Helsmoortel et al.   NATURE GENETICS

Refining analyses of copy number variation identifies specific genes associated with developmental delay

(2014) Bradley P Coe et al.   NATURE GENETICS

Novel Marker for the Onset of Frontotemporal Dementia: Early Increase in Activity-Dependent Neuroprotective Protein (ADNP) in the Face of Tau Mutation

(2014) Yulie Schirer et al.   PLoS One

The rescue of microtubule-dependent traffic recovers mitochondrial function in Parkinson's disease

(2013) A.R. Esteves et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Double-Blind, Placebo-Controlled, Ascending-Dose, Randomized Study to Evaluate the Safety, Tolerability and Effects on Cognition of AL-108 after 12 Weeks of Intranasal Administration in Subjects with Mild Cognitive Impairment

(2013) Bruce H. Morimoto et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Autophagy has a key role in the pathophysiology of schizophrenia

(2013) A Merenlender-Wagner et al.   MOLECULAR PSYCHIATRY

NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy

(2013) S Quraishe et al.   MOLECULAR PSYCHIATRY

NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: Protection against impairments in axonal transport

(2013) Yan Jouroukhin et al.   NEUROBIOLOGY OF DISEASE

Effects of Davunetide on N-acetylaspartate and Choline in Dorsolateral Prefrontal Cortex in Patients with Schizophrenia

(2013) L Fredrik Jarskog et al.   NEUROPSYCHOPHARMACOLOGY

Davunetide: a review of safety and efficacy data with a focus on neurodegenerative diseases

(2013) Bruce H Morimoto et al.   Expert Review of Clinical Pharmacology

Novel Evolutionary-conserved Role for the Activity-dependent Neuroprotective Protein (ADNP) Family That Is Important for Erythropoiesis

(2012) Efrat Dresner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

HP1 Recruits Activity-Dependent Neuroprotective Protein to H3K9me3 Marked Pericentromeric Heterochromatin for Silencing of Major Satellite Repeats

(2011) Kerstin Mosch et al.   PLoS One

Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia

(2011) Daniel C. Javitt et al.   SCHIZOPHRENIA RESEARCH

Neuroprotective effects of NAP against excitotoxic brain damage in the newborn mice: implications for cerebral palsy

(2010) P. Sokolowska et al.   NEUROSCIENCE

NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse—A microtubule-deficient model of schizophrenia

(2010) Avia Merenlender-Wagner et al.   PEPTIDES

Separating derived from ancestral features of mouse and human genomes

(2009) Chris P. Ponting et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Addressing Alzheimers Disease Tangles: From NAP to AL-108

(2009) Illana Gozes et al.   Current Alzheimer Research

NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model

(2009) Natalia Shiryaev et al.   NEUROBIOLOGY OF DISEASE

ADNP Differential Nucleus/Cytoplasm Localization in Neurons Suggests Multiple Roles in Neuronal Differentiation and Maintenance

(2008) Shmuel Mandel et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease

(2008) Y. Matsuoka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Complete Sequence of a Novel Protein Containing a Femtomolar-Activity-Dependent Neuroprotective Peptide

(2003) Merav Bassan et al.   JOURNAL OF NEUROCHEMISTRY