Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer’s pathologies

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

(2014) Alessia Di Nardo et al.   HUMAN MOLECULAR GENETICS

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

(2014) Adam L Boxer et al.   LANCET NEUROLOGY

The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins

(2014) S Oz et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP

(2014) Céline Helsmoortel et al.   NATURE GENETICS

Novel Marker for the Onset of Frontotemporal Dementia: Early Increase in Activity-Dependent Neuroprotective Protein (ADNP) in the Face of Tau Mutation

(2014) Yulie Schirer et al.   PLoS One

Potential Impact ofDSM-5Criteria on Autism Spectrum Disorder Prevalence Estimates

(2014) Matthew J. Maenner et al.   JAMA Psychiatry

Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences

(2014) Michelle Mielke et al.   Clinical Epidemiology

The rescue of microtubule-dependent traffic recovers mitochondrial function in Parkinson's disease

(2013) A.R. Esteves et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NAP Alpha-Aminoisobutyric Acid (IsoNAP)

(2013) Illana Gozes et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy

(2013) S Quraishe et al.   MOLECULAR PSYCHIATRY

Effects of Davunetide on N-acetylaspartate and Choline in Dorsolateral Prefrontal Cortex in Patients with Schizophrenia

(2013) L Fredrik Jarskog et al.   NEUROPSYCHOPHARMACOLOGY

Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E

(2013) Pauline Gosselin et al.   NUCLEIC ACIDS RESEARCH

Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries

(2012) Michael E. Talkowski et al.   CELL

Protection Against Tauopathy by the Drug Candidates NAP (Davunetide) and D-SAL: Biochemical, Cellular and Behavioral Aspects

(2012) Natalia Shiryaev et al.   CURRENT PHARMACEUTICAL DESIGN

Novel Evolutionary-conserved Role for the Activity-dependent Neuroprotective Protein (ADNP) Family That Is Important for Erythropoiesis

(2012) Efrat Dresner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-dependent neuroprotector homeobox protein: A candidate protein identified in serum as diagnostic biomarker for Alzheimer's disease

(2012) Ming-Hui Yang et al.   Journal of Proteomics

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Selective deletion of forebrain glycogen synthase kinase 3  reveals a central role in serotonin-sensitive anxiety and social behaviour

(2012) C. Latapy et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The ADNP Derived Peptide, NAP Modulates the Tubulin Pool: Implication for Neurotrophic and Neuroprotective Activities

(2012) Saar Oz et al.   PLoS One

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort

(2011) Jindan Yu et al.   Behavioral and Brain Functions

The Synaptic Protein Neuroligin-1 Interacts with the Amyloid β-Peptide. Is There a Role in Alzheimer’s Disease?

(2011) Margarita C. Dinamarca et al.   BIOCHEMISTRY

Activity-Dependent Neuroprotective Protein Modulates Its Own Gene Expression

(2011) Moutasem S. Aboonq et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

ZMIZ1 Preferably Enhances the Transcriptional Activity of Androgen Receptor with Short Polyglutamine Tract

(2011) Xiaomeng Li et al.   PLoS One

Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia

(2011) Daniel C. Javitt et al.   SCHIZOPHRENIA RESEARCH

Activity-dependent neuroprotective protein (ADNP) is regulated in the brains of mouse models of human tauopathies: Toward davunetide replacement therapy

(2010) Illana Gozes et al.   Alzheimers & Dementia

A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition

(2010) James Y. Garbern et al.   BRAIN

Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: Deregulation in schizophrenia

(2010) Efrat Dresner et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse—A microtubule-deficient model of schizophrenia

(2010) Avia Merenlender-Wagner et al.   PEPTIDES

Addressing Alzheimers Disease Tangles: From NAP to AL-108

(2009) Illana Gozes et al.   Current Alzheimer Research

NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model

(2009) Natalia Shiryaev et al.   NEUROBIOLOGY OF DISEASE

Expression of Activity-Dependent Neuroprotective Protein in the Immune System: Possible Functions and Relevance to Multiple Sclerosis

(2009) Manjit Braitch et al.   NEUROIMMUNOMODULATION

A novel missense mutation (Leu46Val) of PAX6 found in an autistic patient

(2009) Motoko Maekawa et al.   NEUROSCIENCE LETTERS

Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes

(2008) Yan Dai et al.   CARCINOGENESIS

ADNP Differential Nucleus/Cytoplasm Localization in Neurons Suggests Multiple Roles in Neuronal Differentiation and Maintenance

(2008) Shmuel Mandel et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease

(2008) Y. Matsuoka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Ageing and the regulation of protein synthesis: a balancing act?

(2008) Nektarios Tavernarakis   TRENDS IN CELL BIOLOGY

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR

Complete Sequence of a Novel Protein Containing a Femtomolar-Activity-Dependent Neuroprotective Peptide

(2003) Merav Bassan et al.   JOURNAL OF NEUROCHEMISTRY