On the Molecular Evolution of Leptin, Leptin Receptor, and Endospanin

Leptin expression in mandarin fish Siniperca chuatsi (Basilewsky): Regulation by postprandial and short-term fasting treatment

(2016) Xiaochen Yuan et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Identification of the Long-Sought Leptin in Chicken and Duck: Expression Pattern of the Highly GC-Rich AvianleptinFits an Autocrine/Paracrine Rather Than Endocrine Function

(2016) Eyal Seroussi et al.   ENDOCRINOLOGY

Seasonal and parity effects on ghrelin levels throughout the estrous cycle in dairy cows

(2016) Hen Honig et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Impaired central leptin signaling and sensitivity in rainbow trout with high muscle adiposity

(2016) Ningping Gong et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Stimulation of food intake after central administration of gonadotropin-inhibitory hormone is similar in genetically selected low and high body weight lines of chickens

(2016) Betty R. McConn et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Two isoforms of leptin in the White-clouds Mountain minnow ( Tanichthys albonubes ): Differential regulation by estrogen despite similar response to fasting

(2016) Ting Chen et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Leptin receptor gene in the European sea bass (Dicentrarchus labrax): Cloning, phylogeny, tissue distribution and neuroanatomical organization

(2016) Sebastián Escobar et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Discovery and functional characterization of leptin and its receptors in Japanese quail ( Coturnix japonica )

(2016) Dandan Wang et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales

(2016) H. C. Ball et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Seasonal Control of Mammalian Energy Balance: Recent Advances in the Understanding of Daily Torpor and Hibernation

(2016) M. Jastroch et al.   JOURNAL OF NEUROENDOCRINOLOGY

Modulation of tissue repair by regeneration enhancer elements

(2016) Junsu Kang et al.   NATURE

Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish

(2016) Maximilian Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reverse Genetics in Zebrafish: Mutants, Morphants, and Moving Forward

(2016) Nathan D. Lawson   TRENDS IN CELL BIOLOGY

Fed and fasted chicks from lines divergently selected for low or high body weight have differential hypothalamic appetite-associated factor mRNA expression profiles

(2015) Jiaqing Yi et al.   BEHAVIOURAL BRAIN RESEARCH

The soluble leptin receptor

(2015) Michael Schaab et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Activation of transmembrane cell-surface receptors via a common mechanism? The “rotation model”

(2015) Ichiro N. Maruyama   BIOESSAYS

Roles of leptin and ghrelin in adipogenesis and lipid metabolism of rainbow trout adipocytes in vitro

(2015) Cristina Salmerón et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

Phenomenon of leptin resistance in seasonal animals: the failure of leptin action in the brain

(2015) M. Szczesna et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Effects of nutritional status on plasma leptin levels and in vitro regulation of adipocyte leptin expression and secretion in rainbow trout

(2015) Cristina Salmerón et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Comparative analysis reveals loss of the appetite-regulating peptide hormone ghrelin in falcons

(2015) Inge Seim et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Roles of leptin in bone metabolism and bone diseases

(2015) Xu Xu Chen et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Intracellular leptin signaling following effective weight loss

(2015) Ayse Sahin-Efe et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ensembl Genomes 2016: more genomes, more complexity

(2015) Paul Julian Kersey et al.   NUCLEIC ACIDS RESEARCH

Leptin Manipulation Reduces Appetite and Causes a Switch in Mating Preference in the Plains Spadefoot Toad (Spea bombifrons)

(2015) Nicholas W. Garcia et al.   PLoS One

Duplicated Leptin Receptors in Two Species of Eel Bring New Insights into the Evolution of the Leptin System in Vertebrates

(2015) Marina Morini et al.   PLoS One

Seasonal Differences in Relative Gene Expression of Putative Central Appetite Regulators in Arctic Charr (Salvelinus alpinus) Do Not Reflect Its Annual Feeding Cycle

(2015) Anja Striberny et al.   PLoS One

Avian blood induced intranuclear translocation of STAT3 via the chicken leptin receptor

(2014) Takeshi Ohkubo et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Ancient Origins and Evolutionary Conservation of Intracellular and Neural Signaling Pathways Engaged by the Leptin Receptor

(2014) Melissa Y. Cui et al.   ENDOCRINOLOGY

Discovery of a Novel Functional Leptin Protein (LEP) in Zebra Finches: Evidence for the Existence of an Authentic Avian Leptin Gene Predominantly Expressed in the Brain and Pituitary

(2014) Guian Huang et al.   ENDOCRINOLOGY

Discovery and Characterization of the First Genuine Avian Leptin Gene in the Rock Dove (Columba livia)

(2014) Miriam Friedman-Einat et al.   ENDOCRINOLOGY

Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice

(2014) V Vauthier et al.   GENE THERAPY

Prolactin is a major inhibitor of hepatic Leptin A synthesis and secretion: Studies utilizing a homologous Leptin A ELISA in the tilapia

(2014) Jonathan D. Douros et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Comparative endocrinology of leptin: Assessing function in a phylogenetic context

(2014) Richard L. Londraville et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

(2014) A. Veloso et al.   GENOME RESEARCH

Polymorphisms of Leptin-b Gene Associated with Growth Traits in Orange-Spotted Grouper (Epinephelus coioides)

(2014) Hai Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Leptin in teleostean fish, towards the origins of leptin physiology

(2014) Marnix Gorissen et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Krogh 1929 or 'The Krogh Principle'

(2014) S. Lindstedt   JOURNAL OF EXPERIMENTAL BIOLOGY

The Loss of Adipokine Genes in the Chicken Genome and Implications for Insulin Metabolism

(2014) Nataša Đaković et al.   MOLECULAR BIOLOGY AND EVOLUTION

NIH working group report: Innovative research to improve maintenance of weight loss

(2014) Paul S. MacLean et al.   Obesity

Discovery of the Elusive Leptin in Birds: Identification of Several ‘Missing Links’ in the Evolution of Leptin and Its Receptor

(2014) Jeremy W. Prokop et al.   PLoS One

Leptin receptor signaling inhibits ovarian follicle development and egg laying in chicken hens

(2014) Ming M Lei et al.   Reproductive Biology and Endocrinology

Structural and Mechanistic Paradigm of Leptin Receptor Activation Revealed by Complexes with Wild-Type and Antagonist Leptins

(2014) Kedar Moharana et al.   STRUCTURE

Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

(2013) Waseem Akhtar et al.   CELL

Alternative Splice Variants of the Rainbow Trout Leptin Receptor Encode Multiple Circulating Leptin-Binding Proteins

(2013) Ningping Gong et al.   ENDOCRINOLOGY

Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder

(2013) Eduardo N. Fuentes et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Leptin receptor-deficient (knockout) medaka, Oryzias latipes, show chronical up-regulated levels of orexigenic neuropeptides, elevated food intake and stage specific effects on growth and fat allocation

(2013) Shin-ichi Chisada et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Pegylated leptin antagonist with strong orexigenic activity in mice is not effective in chickens

(2013) A. Gertler et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

A systematic genome-wide analysis of zebrafish protein-coding gene function

(2013) Ross N. W. Kettleborough et al.   NATURE

Three-Phase Fuel Deposition in a Long-Distance Migrant, the Red Knot (Calidris canutus piersmai), before the Flight to High Arctic Breeding Grounds

(2013) Ning Hua et al.   PLoS One

Role of leptin receptors in granulosa cells during ovulation

(2013) Lisa Dupuis et al.   REPRODUCTION

Novel interaction of Rab13 and Rab8 with endospanins

(2013) Mirkka J. Hirvonen et al.   FEBS Open Bio

Leptin expression affects metabolic rate in zebrafish embryos (D. rerio)

(2013) Mark R. Dalman et al.   Frontiers in Physiology

Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor

(2013) Zhiying Li et al.   Molecular Metabolism

Ghrelin and leptin modulate the feeding behaviour of the hawksbill turtle Eretmochelys imbricata during nesting season

(2013) D. W. Goldberg et al.   Conservation Physiology

Expression of leptin and its receptor genes in the ovarian follicles of cycling and early pregnant pigs

(2012) N. Smolinska et al.   Animal

Drosophila Cytokine Unpaired 2 Regulates Physiological Homeostasis by Remotely Controlling Insulin Secretion

(2012) Akhila Rajan et al.   CELL

Seasonal appetite regulation in the anadromous Arctic charr: Evidence for a role of adiposity in the regulation of appetite but not for leptin in signalling adiposity

(2012) Eirik Frøiland et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Knockdown of leptin A expression dramatically alters zebrafish development

(2012) Qin Liu et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Ligand-Induced Architecture of the Leptin Receptor Signaling Complex

(2012) Liliya V. Mancour et al.   MOLECULAR CELL

Leptin and leptin receptor: Analysis of a structure to function relationship in interaction and evolution from humans to fish

(2012) J.W. Prokop et al.   PEPTIDES

Effects of long-term restricted feeding on plasma leptin, hepatic leptin expression and leptin receptor expression in juvenile Atlantic salmon (Salmo salar L.)

(2011) Susanne Trombley et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Endospanins Regulate a Postinternalization Step of the Leptin Receptor Endocytic Pathway

(2011) Karin Séron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The regulation of food intake in mammalian hibernators: a review

(2011) Gregory L. Florant et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evolution of Leptin Structure and Function

(2011) Robert J. Denver et al.   NEUROENDOCRINOLOGY

Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila

(2011) T. Copf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin in Teleost Fishes: An Argument for Comparative Study

(2011) Donald L. Copeland et al.   Frontiers in Physiology

The chicken LEP (OB) gene has not been mapped

(2010) F Pitel et al.   ANIMAL GENETICS

Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus

(2010) Jae-Pil Jeon et al.   BMC GENOMICS

Leptin and leptin receptor genes in Atlantic salmon: Cloning, phylogeny, tissue distribution and expression correlated to long-term feeding status

(2010) Ivar Rønnestad et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Decreased blood–brain leptin transfer in an ovine model of obesity and weight loss: resolving the cause of leptin resistance

(2010) C L Adam et al.   INTERNATIONAL JOURNAL OF OBESITY

Lack of leptin activity in blood samples of Adélie penguin and bar-tailed godwit

(2010) Sara Yosefi et al.   JOURNAL OF ENDOCRINOLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Leptin mRNA and Protein Immunoreactivity in Adipose Tissue and Liver of Rainbow Trout(Oncorhynchus mykiss) and Immunohistochemical Localization in Liver

(2009) B. Pfundt et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Isolation of a novel leptin receptor gene promoter preferentially functioning in neuronal cells

(2009) Tetsurou Satoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Leptin stimulatesXenopuslung development: evolution in a dish

(2009) J.S. Torday et al.   EVOLUTION & DEVELOPMENT

A homologous salmonid leptin radioimmunoassay indicates elevated plasma leptin levels during fasting of rainbow trout

(2009) Peter Kling et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Is there a leptin gene in the chicken genome? Lessons from phylogenetics, bioinformatics and genomics

(2009) Frédérique Pitel et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice

(2009) Thierry Touvier et al.   JOURNAL OF CLINICAL INVESTIGATION

Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution

(2009) Marnix Gorissen et al.   JOURNAL OF ENDOCRINOLOGY

The expression of leptin and its receptor during different physiological stages in the bovine ovary

(2009) M. Sarkar et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8

(2009) Elmar Krieger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Leptin resistance: a prediposing factor for diet-induced obesity

(2008) Philip J. Scarpace et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family

(2008) N. Danilova et al.   BLOOD

Production of recombinant leptin and its effects on food intake in rainbow trout (Oncorhynchus mykiss)

(2008) Koji Murashita et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Leptin effects on testis and epididymis in the lizard Podarcis sicula, during summer regression

(2008) Rosalba Putti et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells

(2008) Rita L. Nokes et al.   JOURNAL OF CELL BIOLOGY

Global Analysis of Yeast Endosomal Transport Identifies the Vps55/68 Sorting Complex

(2008) Cayetana Schluter et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology