Chemotherapeutic tumor microparticles combining low-dose irradiation reprogram tumor-promoting macrophages through a tumor-repopulating cell-curtailing pathway

Cancer Stem Cells: Basic Concepts and Therapeutic Implications

(2016) Dany Nassar et al.   Annual Review of Pathology-Mechanisms of Disease

Delivery of oncolytic adenovirus into the nucleus of tumorigenic cells by tumor microparticles for virotherapy

(2016) Li Ran et al.   BIOMATERIALS

A Breakthrough: Macrophage-Directed Cancer Immunotherapy

(2016) C. D. Mills et al.   CANCER RESEARCH

Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles

(2016) Jingwei Ma et al.   CELL RESEARCH

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

Filling the Tank: Keeping Antitumor T Cells Metabolically Fit for the Long Haul

(2016) G. M. Delgoffe   Cancer Immunology Research

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression

(2016) Ruihua Ma et al.   OncoImmunology

Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors

(2015) Y. Li et al.   CANCER RESEARCH

Brief Report: Human Mesenchymal Stem-Like Cells Facilitate Floating Tumorigenic Cell Growth via Glutamine-Ammonium Cycle

(2015) Ke Tang et al.   STEM CELLS

The origin and function of tumor-associated macrophages

(2014) Yang Liu et al.   Cellular & Molecular Immunology

Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression

(2014) Youhua Tan et al.   Nature Communications

Complement-Dependent Modulation of Antitumor Immunity following Radiation Therapy

(2014) Michelle Elvington et al.   Cell Reports

Radiotherapy and the Tumor Stroma: The Importance of Dose and Fractionation

(2014) Turid Hellevik et al.   Frontiers in Oncology

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy

(2013) Felix Klug et al.   CANCER CELL

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift

(2013) Silvia C. Formenti et al.   JNCI-Journal of the National Cancer Institute

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

Harnessing the Power of the Immune System to Target Cancer

(2012) Gregory Lizée et al.   Annual Review of Medicine

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

Interaction between regulatory T cells and cancer stem cells

(2012) Xiaozhou Yu et al.   INTERNATIONAL JOURNAL OF CANCER

Soft fibrin gels promote selection and growth of tumorigenic cells

(2012) Jing Liu et al.   NATURE MATERIALS

T cell homing to epithelial barriers in allergic disease

(2012) Sabina A Islam et al.   NATURE MEDICINE

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles

(2012) Ke Tang et al.   Nature Communications

TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b

(2012) Dapeng Li et al.   OncoImmunology

Irradiation Promotes an M2 Macrophage Phenotype in Tumor Hypoxia

(2012) Chi-Shiun Chiang et al.   Frontiers in Oncology

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

(2011) Lucia De Monte et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model

(2010) Zhuoshun Yang et al.   PLoS One

Gamma-Ray Resistance of Regulatory CD4+CD25+Foxp3+T Cells in Mice

(2009) Yanyan Qu et al.   RADIATION RESEARCH

Immunogenic cancer cell death: a key-lock paradigm

(2008) Antoine Tesniere et al.   CURRENT OPINION IN IMMUNOLOGY