Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

(2016) Oksana Gerlits et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Macromolecular structure phasing by neutron anomalous diffraction

(2016) Maxime G. Cuypers et al.   Scientific Reports

Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state

(2016) Steven Dajnowicz et al.   Acta Crystallographica Section D-Structural Biology

High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution

(2016) E. I. Howard et al.   IUCrJ

Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer

(2015) Ryszard Michalczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography

(2015) Qun Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sub-atomic resolution X-ray crystallography and neutron crystallography: promise, challenges and potential

(2015) Matthew P. Blakeley et al.   IUCrJ

Energy optimization of a regular macromolecular crystallography beamline for ultra-high-resolution crystallography

(2015) Gerd Rosenbaum et al.   JOURNAL OF SYNCHROTRON RADIATION

L-Arabinose Binding, Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study

(2014) Paul Langan et al.   STRUCTURE

Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein

(2014) Melina Haupt et al.   IUCrJ

The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography

(2013) Flora Meilleur et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Joint X-ray/Neutron Crystallographic Study of HIV-1 Protease with Clinical Inhibitor Amprenavir: Insights for Drug Design

(2013) Irene T. Weber et al.   JOURNAL OF MEDICINAL CHEMISTRY

Near-Atomic Resolution Neutron Crystallography on PerdeuteratedPyrococcus furiosusRubredoxin: Implication of Hydronium Ions and Protonation State Equilibria in Redox Changes

(2012) M. G. Cuypers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neutron Diffraction of Acetazolamide-Bound Human Carbonic Anhydrase II Reveals Atomic Details of Drug Binding

(2012) S. Zoë Fisher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fourth-generation spallation neutron target-moderator-reflector-shield assembly at the Manuel Lujan Jr. neutron scattering center

(2012) M. Mocko et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography

(2012) J. C.- H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid visualization of hydrogen positions in protein neutron crystallographic structures

(2011) Parthapratim Munshi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal structure of small protein crambin at 0.48 Å resolution

(2011) Andrea Schmidt et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH Values

(2011) Andrey Y. Kovalevsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network “Switch” Is Observed between pH 7.8 and 10.0

(2011) Zoë Fisher et al.   BIOCHEMISTRY

Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface

(2011) Eduardo I. Howard et al.   JOURNAL OF MOLECULAR RECOGNITION

Reintroducing Electrostatics into Macromolecular Crystallographic Refinement: Application to Neutron Crystallography and DNA Hydration

(2011) Timothy D. Fenn et al.   STRUCTURE

Neutron macromolecular crystallography with LADI-III

(2010) Matthew P. Blakeley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A history of neutrons in biology: the development of neutron protein crystallography at BNL and LANL

(2010) Benno P. Schoenborn   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies

(2010) Isabelle Petit-Haertlein et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction

(2010) Marc-Michael Blum et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)—Comparison with related β-propeller enzymes

(2010) Marc-Michael Blum et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation

(2010) Stephen J. Tomanicek et al.   FEBS LETTERS

Experimental measurement of the neutron time-emission spectra at the Manuel Lujan Jr. Neutron Scattering Center

(2010) M. Mocko et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer

(2010) N. Sukumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study

(2010) Andrey Y. Kovalevsky et al.   STRUCTURE

Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules

(2009) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein

(2009) Isabelle Petit-Haertlein et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Neutron Structure of Human Carbonic Anhydrase II: Implications for Proton Transfer

(2009) S. Zoë Fisher et al.   BIOCHEMISTRY

Reversed Enantioselectivity of Diisopropyl Fluorophosphatase against Organophosphorus Nerve Agents by Rational Design

(2009) Marco Melzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid determination of hydrogen positions and protonation states of diisopropyl fluorophosphatase by joint neutron and X-ray diffraction refinement

(2009) Marc-Michael Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutron macromolecular crystallography

(2009) M.P. Blakeley   Crystallography Reviews

Hydrogen Location in Stages of an Enzyme-Catalyzed Reaction: Time-of-Flight Neutron Structure ofd-Xylose Isomerase with Boundd-Xylulose†‡

(2008) Andrey Y. Kovalevsky et al.   BIOCHEMISTRY

Protein structures by spallation neutron crystallography

(2008) Paul Langan et al.   JOURNAL OF SYNCHROTRON RADIATION

The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-ray Diffraction

(2008) Leighton Coates et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY