Nrf2: a potential therapeutic target for diabetic neuropathy

Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats

(2016) Ruifeng Tian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathway

(2015) Edward E. Schmidt   BIOCHEMICAL SOCIETY TRANSACTIONS

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Epigenetic regulation of Keap1-Nrf2 signaling

(2015) Yue Guo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetes

(2015) Elango Bhakkiyalakshmi et al.   PHARMACOLOGICAL RESEARCH

Heme oxygenase-1, a novel target for the treatment of diabetic complications: focus on diabetic peripheral neuropathy

(2015) Geeta Negi et al.   PHARMACOLOGICAL RESEARCH

Effect of Redox Modulating NRF2 Activators on Chronic Kidney Disease

(2014) Bo-hyun Choi et al.   MOLECULES

Dietary Regulation of Keap1/Nrf2/ARE Pathway: Focus on Plant-Derived Compounds and Trace Minerals

(2014) Amanda Stefanson et al.   Nutrients

Antihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients

(2013) Ali Movahed et al.   Evidence-based Complementary and Alternative Medicine

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats

(2013) Susana González-Reyes et al.   Oxidative Medicine and Cellular Longevity

Renoprotective effect of the antioxidant curcumin: Recent findings

(2013) Joyce Trujillo et al.   Redox Biology

Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: roles of Nrf2 and NF-κB

(2012) Yuehui Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis

(2012) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

(2011) Subash C Gupta et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Nrf2 and NF-κB Modulation by Sulforaphane Counteracts Multiple Manifestations of Diabetic Neuropathy in Rats and High Glucose-Induced Changes

(2011) Geeta Negi et al.   CURRENT NEUROVASCULAR RESEARCH

Nrf2 Activators as Attractive Therapeutics for Diabetic Nephropathy: FIG. 1.

(2011) Judy B. de Haan   DIABETES

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

Cinnamaldehyde protects from the hypertension associated with diabetes

(2011) Hany M. El-Bassossy et al.   FOOD AND CHEMICAL TOXICOLOGY

Cinnamaldehyde Enhances Nrf2 Nuclear Translocation to Upregulate Phase II Detoxifying Enzyme Expression in HepG2 Cells

(2011) Tzou-Chi Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Chemistry of the Cysteine Sensors in Kelch-Like ECH-Associated Protein 1

(2010) Ryan Holland et al.   ANTIOXIDANTS & REDOX SIGNALING

Grapes, Wines, Resveratrol, and Heart Health

(2009) Alberto A A Bertelli et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response

(2009) Z. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Aldose Reductase, Still a Compelling Target for Diabetic Neuropathy

(2008) Peter Oates   CURRENT DRUG TARGETS

The Antioxidant Response as a Drug Target in Diabetic Neuropathy

(2008) Andrea Vincent et al.   CURRENT DRUG TARGETS

Pro-Inflammatory Mechanisms in Diabetic Neuropathy: Focus on the Nuclear Factor Kappa B Pathway

(2008) Norman Cameron et al.   CURRENT DRUG TARGETS

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

(2008) Georg T. Wondrak et al.   FREE RADICAL BIOLOGY AND MEDICINE

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy

(2008) Shyam S. Sharma et al.   LIFE SCIENCES

Sulforaphane protects against cytokine- and streptozotocin-induced β-cell damage by suppressing the NF-κB pathway

(2008) Mi-Young Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY