Spinocerebellar Ataxia Type 2 Is Associated with the Extracellular Loss of Superoxide Dismutase but Not Catalase Activity

Evidence of oxidative stress and mitochondrial dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts: Effect of coenzyme Q10 supplementation on these parameters

(2017) Nanna Cornelius et al.   MITOCHONDRION

Mesenchymal Stem Cells Improve Motor Functions and Decrease Neurodegeneration in Ataxic Mice

(2015) Jonathan Jones et al.   MOLECULAR THERAPY

Direct Binding of Ataxin-2 to Distinct Elements in 3′ UTRs Promotes mRNA Stability and Protein Expression

(2014) Moe Yokoshi et al.   MOLECULAR CELL

Consensus Paper: Pathological Mechanisms Underlying Neurodegeneration in Spinocerebellar Ataxias

(2013) A. Matilla-Dueñas et al.   CEREBELLUM

Association between Machado–Joseph disease and oxidative stress biomarkers

(2013) Laura Segabinazzi Pacheco et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

(2013) Robert P Mason et al.   NATURE GENETICS

Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model

(2012) Abiodun Ajayi et al.   BMC NEUROSCIENCE

Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

(2012) A. Valencia et al.   HUMAN MOLECULAR GENETICS

In Vitroandin VivoAggregation of a Fragment of Huntingtin Protein Directly Causes Free Radical Production

(2011) Sarah Hands et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress and Cell Membranes in the Pathogenesis of Alzheimer's Disease

(2011) Paul H. Axelsen et al.   PHYSIOLOGY

The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation

(2011) C. McCann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Friedreich Ataxia: Molecular Mechanisms, Redox Considerations, and Therapeutic Opportunities

(2010) Renata Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Downregulation of NF-κB signaling by mutant huntingtin proteins induces oxidative stress and cell death

(2010) Sami Reijonen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Early and Late Events Induced by PolyQ-expanded Proteins

(2010) Alessandra Bertoni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival

(2009) Kevin Kemp et al.   JOURNAL OF NEUROCHEMISTRY

Decreased antioxidant enzyme activity and increased mitochondrial DNA damage in cellular models of Machado-Joseph disease

(2009) Ya-Chun Yu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Molecular epidemiology of spinocerebellar ataxias in Cuba: Insights into SCA2 founder effect in Holguin

(2009) Luis Velázquez Pérez et al.   NEUROSCIENCE LETTERS