Guanabenz Prevents d-Galactosamine/Lipopolysaccharide-Induced Liver Damage and Mortality

Harnessing the integrated stress response for the treatment of multiple sclerosis

(2016) Sharon W Way et al.   LANCET NEUROLOGY

GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation

(2016) S Ito et al.   Cell Death & Disease

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure

(2015) Jianhua Rao et al.   BIOCHEMICAL JOURNAL

Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model

(2015) Nana Chen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Growth arrest and DNA damage-inducible 34 regulates liver regeneration in hepatic steatosis in mice

(2015) Yuka Inaba et al.   HEPATOLOGY

Ocean acidification and the Permo-Triassic mass extinction

(2015) M. O. Clarkson et al.   SCIENCE

Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

(2015) Sharon W. Way et al.   Nature Communications

Vasopressors for the Treatment of Septic Shock: Systematic Review and Meta-Analysis

(2015) Tomer Avni et al.   PLoS One

The Role of the Liver in Sepsis

(2014) Jun Yan et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis

(2014) Lijun Wang et al.   NEUROBIOLOGY OF DISEASE

Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes

(2014) Christiane Neuber et al.   PLoS One

Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury

(2014) Sujata Saraswat Ohri et al.   PLoS One

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

(2014) M. N. Lee et al.   SCIENCE

Mapping the crossroads of immune activation and cellular stress response pathways

(2013) Nuno Cláudio et al.   EMBO JOURNAL

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Host innate immune responses to sepsis

(2013) Willem Joost Wiersinga et al.   Virulence

Signaling Organelles of the Innate Immune System

(2012) Jonathan C. Kagan   CELL

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

(2012) Hideo Negishi et al.   NATURE IMMUNOLOGY

Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells

(2012) G. Clavarino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the subcellular sites of innate immune signal transduction

(2012) Jonathan C. Kagan   TRENDS IN IMMUNOLOGY

Induction of GADD34 Is Necessary for dsRNA-Dependent Interferon-β Production and Participates in the Control of Chikungunya Virus Infection

(2012) Giovanna Clavarino et al.   PLoS Pathogens

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Severe sepsis in cirrhosis

(2009) Thierry Gustot et al.   HEPATOLOGY