Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-07-05
DOI
10.3389/fimmu.2017.00537
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding
- (2017) Patrick Koenig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
- (2016) Mattia Bonsignori et al. CELL
- Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires
- (2016) Ming Tian et al. CELL
- A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data
- (2016) Ang Cui et al. JOURNAL OF IMMUNOLOGY
- Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection
- (2016) Zizhang Sheng et al. PLoS Computational Biology
- Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation
- (2016) Duncan K. Ralph et al. PLoS Computational Biology
- SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts
- (2016) Chaim A. Schramm et al. Frontiers in Immunology
- Denoising DNA deep sequencing data—high-throughput sequencing errors and their correction
- (2015) David Laehnemann et al. BRIEFINGS IN BIOINFORMATICS
- Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes
- (2015) Leng-Siew Yeap et al. CELL
- Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
- (2015) Xueling Wu et al. CELL
- Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
- (2015) Jinal N Bhiman et al. NATURE MEDICINE
- Restricted, canonical, stereotyped and convergent immunoglobulin responses
- (2015) Carole J. Henry Dunand et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Inferring processes underlying B-cell repertoire diversity
- (2015) Yuval Elhanati et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Quantifying evolutionary constraints on B-cell affinity maturation
- (2015) Connor O. McCoy et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- AID targeting: old mysteries and new challenges
- (2015) Vivek Chandra et al. TRENDS IN IMMUNOLOGY
- Optimizing antibody expression by using the naturally occurring framework diversity in a live bacterial antibody display system
- (2015) T. Noelle Lombana et al. Scientific Reports
- Antibody-Specific Model of Amino Acid Substitution for Immunological Inferences from Alignments of Antibody Sequences
- (2014) Alexander Mirsky et al. MOLECULAR BIOLOGY AND EVOLUTION
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
- (2013) Florian Klein et al. CELL
- Integrating B Cell Lineage Information into Statistical Tests for Detecting Selection in Ig Sequences
- (2013) M. Uduman et al. JOURNAL OF IMMUNOLOGY
- Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data
- (2013) Gur Yaari et al. Frontiers in Immunology
- High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals
- (2012) B S Briney et al. GENES AND IMMUNITY
- Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes
- (2012) Bryan S. Briney et al. PLoS One
- A Mechanism for TCR Sharing between T Cell Subsets and Individuals Revealed by Pyrosequencing
- (2011) Vanessa Venturi et al. JOURNAL OF IMMUNOLOGY
- Somatic hypermutation targeting is influenced by location within the immunoglobulin V region
- (2011) Reuma Magori Cohen et al. MOLECULAR IMMUNOLOGY
- Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
- (2011) X. Wu et al. SCIENCE
- Search and clustering orders of magnitude faster than BLAST
- (2010) Robert C. Edgar BIOINFORMATICS
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Two levels of protection for the B cell genome during somatic hypermutation
- (2008) Man Liu et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started