Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8+ T-Cell Repertoire in Older People

Presentation of a Conserved Adenoviral Epitope on HLA-C*0702 Allows Evasion of Natural Killer but Not T Cell Responses

(2017) Anna Keib et al.   VIRAL IMMUNOLOGY

Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium

(2016) Annette Pachnio et al.   PLoS Pathogens

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

(2016) Yen-Ling Chiu et al.   Scientific Reports

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

(2015) Amir Horowitz et al.   JOURNAL OF IMMUNOLOGY

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

(2015) Prakash K. Gupta et al.   PLoS Pathogens

Cytomegalovirus Infection and Memory T Cell Inflation

(2015) Jihye Kim et al.   Immune Network

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

(2014) Michael P. Weekes et al.   CELL

Classical and non-classical MHC I molecule manipulation by human cytomegalovirus: so many targets—but how many arrows in the quiver?

(2014) Anne Halenius et al.   Cellular & Molecular Immunology

CD8 T Cell-Evasive Functions of Human Cytomegalovirus Display Pervasive MHC Allele Specificity, Complementarity, and Cooperativity

(2014) S. Ameres et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus infection is associated with increased mortality in the older population

(2013) George M. Savva et al.   AGING CELL

Viral inoculum dose impacts memory T-cell inflation

(2013) Anke Redeker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Competition for Antigen at the Level of the APC Is a Major Determinant of Immunodominance during Memory Inflation in Murine Cytomegalovirus Infection

(2013) L. A. Farrington et al.   JOURNAL OF IMMUNOLOGY

The Context of Gene Expression Defines the Immunodominance Hierarchy of Cytomegalovirus Antigens

(2013) I. Dekhtiarenko et al.   JOURNAL OF IMMUNOLOGY

Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA

(2013) S. J. Griffiths et al.   JOURNAL OF IMMUNOLOGY

Immunoprevalence and Immunodominance of HLA-Cw*0801-Restricted T Cell Response Targeting the Hepatitis B Virus Envelope Transmembrane Region

(2013) A. T. Tan et al.   JOURNAL OF VIROLOGY

Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion

(2013) Stefanie Ameres et al.   PLoS Pathogens

The inverted CD4/CD8 ratio and associated parameters in 66-year-old individuals: the Swedish HEXA immune study

(2012) J. Strindhall et al.   AGE

Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?

(2012) Selena Viganò et al.   Clinical & Developmental Immunology

Evaluating Cellular Polyfunctionality with a Novel Polyfunctionality Index

(2012) Martin Larsen et al.   PLoS One

HLA-C as a mediator of natural killer and T-cell activation: spectator or key player?

(2011) Marie-Eve Blais et al.   IMMUNOLOGY

Cytomegalovirus-Specific T Cell Immunity Is Maintained in Immunosenescent Rhesus Macaques

(2011) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

(2011) R. Lachmann et al.   JOURNAL OF VIROLOGY

Differential microRNA regulation of HLA-C expression and its association with HIV control

(2011) Smita Kulkarni et al.   NATURE

Seropositivity to Cytomegalovirus, Inflammation, All-Cause and Cardiovascular Disease-Related Mortality in the United States

(2011) Amanda M. Simanek et al.   PLoS One

Counteraction of HLA-C-Mediated Immune Control of HIV-1 by Nef

(2010) A. Specht et al.   JOURNAL OF VIROLOGY

Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals

(2009) S. Chidrawar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunobiology of Human Cytomegalovirus: from Bench to Bedside

(2009) T. Crough et al.   CLINICAL MICROBIOLOGY REVIEWS

Inflation and Long-Term Maintenance of CD8 T Cells Responding to a Latent Herpesvirus Depend upon Establishment of Latency and Presence of Viral Antigens

(2009) A. Lang et al.   JOURNAL OF IMMUNOLOGY

CMV-Specific TCR-Transgenic T Cells for Immunotherapy

(2009) A. Schub et al.   JOURNAL OF IMMUNOLOGY

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

(2009) Rasmi Thomas et al.   NATURE GENETICS

Immune evasion proteins gpUS2 and gpUS11 of human cytomegalovirus incompletely protect infected cells from CD8 T cell recognition

(2009) K. Besold et al.   VIROLOGY

CMV and the Art of Memory Maintenance

(2008) Paul Klenerman et al.   IMMUNITY