Classical and non-classical MHC I molecule manipulation by human cytomegalovirus: so many targets—but how many arrows in the quiver?

Effect of NKG2D ligand expression on host immune responses

(2015) Marine Champsaur et al.   IMMUNOLOGICAL REVIEWS

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

(2014) Michael P. Weekes et al.   CELL

Human Cytomegalovirus Regulates Surface Expression of the Viral Protein UL18 by Means of Two Motifs Present in the Cytoplasmic Tail

(2014) M. Maffei et al.   JOURNAL OF IMMUNOLOGY

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I

(2014) D. J. H. van den Boomen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

(2014) Michael L. van de Weijer et al.   Nature Communications

Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation

(2014) Ceri A. Fielding et al.   PLoS Pathogens

Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III

(2014) Eugenia Corrales-Aguilar et al.   PLoS Pathogens

MicroRNA Editing Facilitates Immune Elimination of HCMV Infected Cells

(2014) Daphna Nachmani et al.   PLoS Pathogens

Some Basic Aspects of HLA-G Biology

(2014) Estibaliz Alegre et al.   Journal of Immunology Research

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

(2013) V. Beziat et al.   BLOOD

MAITs, MR1 and vitamin B metabolites

(2013) Richard W Birkinshaw et al.   CURRENT OPINION IN IMMUNOLOGY

A natural tapasin isoform lacking exon 3 modifies peptide loading complex function

(2013) Nele Beutler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells

(2013) Susan L. Heatley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cytomegalovirus pp71 Stimulates Major Histocompatibility Complex Class I Presentation of IE1-Derived Peptides at Immediate Early Times of Infection

(2013) J. Hesse et al.   JOURNAL OF VIROLOGY

Human cytomegalovirus (HCMV) US2 protein interacts with human CD1d (hCD1d) and down-regulates invariant NKT (iNKT) cell activity

(2013) Jihye Han et al.   MOLECULES AND CELLS

The C-Terminal Amino Acid of the MHC-I Heavy Chain Is Critical for Binding to Derlin-1 in Human Cytomegalovirus US11-Induced MHC-I Degradation

(2013) Sunglim Cho et al.   PLoS One

Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion

(2013) Stefanie Ameres et al.   PLoS Pathogens

Forced interaction of cell surface proteins with Derlin-1 in the endoplasmic reticulum is sufficient to induce their dislocation into the cytosol for degradation

(2012) Sunglim Cho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex

(2012) Sabine Hulpke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamics of Major Histocompatibility Complex Class I Association with the Human Peptide-loading Complex

(2012) Michaela S. Panter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cytomegalovirus UL40 Signal Peptide Regulates Cell Surface Expression of the NK Cell Ligands HLA-E and gpUL18

(2012) V. Prod'homme et al.   JOURNAL OF IMMUNOLOGY

The Impact of a Large and Frequent Deletion in the Human TCR   Locus on Antiviral Immunity

(2012) R. M. Brennan et al.   JOURNAL OF IMMUNOLOGY

Human Cytomegalovirus Infection of M1 and M2 Macrophages Triggers Inflammation and Autologous T-Cell Proliferation

(2012) C. Bayer et al.   JOURNAL OF VIROLOGY

Human cytomegalovirus US3 modulates destruction of MHC class I molecules

(2012) Vanessa M. Noriega et al.   MOLECULAR IMMUNOLOGY

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

(2012) Margit H. Lampen et al.   MOLECULAR IMMUNOLOGY

Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor

(2012) Carrie R Willcox et al.   NATURE IMMUNOLOGY

Decoding Human Cytomegalovirus

(2012) N. Stern-Ginossar et al.   SCIENCE

The tolerogenic interplay(s) among HLA-G, myeloid APCs, and regulatory cells

(2011) E. D. Carosella et al.   BLOOD

HLA-C as a mediator of natural killer and T-cell activation: spectator or key player?

(2011) Marie-Eve Blais et al.   IMMUNOLOGY

Tapasin Discriminates Peptide-Human Leukocyte Antigen-A*02:01 Complexes Formed with Natural Ligands

(2011) Gustav Roder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC-I-Like Molecules in the Evasion of Natural Killer Cell Surveillance

(2011) Maria Jamela Revilleza et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription

(2011) A. Halenius et al.   JOURNAL OF VIROLOGY

High-Resolution Profiling and Analysis of Viral and Host Small RNAs during Human Cytomegalovirus Infection

(2011) T. J. Stark et al.   JOURNAL OF VIROLOGY

Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses

(2011) Marieke C. Verweij et al.   MOLECULAR IMMUNOLOGY

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1

(2011) Sungchul Kim et al.   NATURE IMMUNOLOGY

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

(2010) G. Magri et al.   BLOOD

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

(2010) S. Gregori et al.   BLOOD

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

(2010) Boyoun Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intracellular Sequestration of the NKG2D Ligand ULBP3 by Human Cytomegalovirus

(2010) N. J. Bennett et al.   JOURNAL OF IMMUNOLOGY

Structure of the HCMV UL16-MICB Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse NKG2D Ligands

(2010) Steffen Müller et al.   PLoS Pathogens

The NKG2D ligand ULBP4 binds to TCR 9/ 2 and induces cytotoxicity to tumor cells through both TCR   and NKG2D

(2009) Y. Kong et al.   BLOOD

Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation

(2009) Seong-Ok Lee et al.   EMBO JOURNAL

ULBP6/RAET1L is an additional human NKG2D ligand

(2009) Robert A. Eagle et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

(2009) Gang Dong et al.   IMMUNITY

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

(2009) Helen R. Stagg et al.   JOURNAL OF CELL BIOLOGY

NKG2D Ligand MICA Is Retained in the cis-Golgi Apparatus by Human Cytomegalovirus Protein UL142

(2009) O. Ashiru et al.   JOURNAL OF VIROLOGY

Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6

(2008) G. E. Dugan et al.   JOURNAL OF VIROLOGY

Inhibition of CD1 Antigen Presentation by Human Cytomegalovirus

(2008) M. J. Raftery et al.   JOURNAL OF VIROLOGY

Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor

(2008) Z. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for NKG2A/CD94 recognition of HLA-E

(2008) B. K. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UL40 Human Cytomegalovirus Variability Evolution Patterns Over Time in Renal Transplant Recipients

(2008) Isabelle Garrigue et al.   TRANSPLANTATION

Human Cytomegalovirus UL18 Utilizes US6 for Evading the NK and T-Cell Responses

(2008) Youngkyun Kim et al.   PLoS Pathogens

Signal Peptide-Dependent Inhibition of MHC Class I Heavy Chain Translation by Rhesus Cytomegalovirus

(2008) Colin J. Powers et al.   PLoS Pathogens