Unique Features of Pancreatic-Resident Regulatory T Cells in Autoimmune Type 1 Diabetes
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Unique Features of Pancreatic-Resident Regulatory T Cells in Autoimmune Type 1 Diabetes
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-09-29
DOI
10.3389/fimmu.2017.01235
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Generation of human islet-specific regulatory T cells by TCR gene transfer
- (2017) Caroline M. Hull et al. JOURNAL OF AUTOIMMUNITY
- TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs
- (2017) William F. Hawse et al. JOURNAL OF IMMUNOLOGY
- Stability and function of regulatory T cells expressing the transcription factor T-bet
- (2017) Andrew G. Levine et al. NATURE
- Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression
- (2017) Guido Sebastiani et al. Scientific Reports
- Tissue Tregs
- (2016) Marisella Panduro et al. Annual Review of Immunology
- Characterization of resident lymphocytes in human pancreatic islets
- (2016) M. Radenkovic et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The Expanding Role of Natural Killer Cells in Type 1 Diabetes and Immunotherapy
- (2016) Chris Fraker et al. Current Diabetes Reports
- A Regulatory T-Cell Gene Signature Is a Specific and Sensitive Biomarker to Identify Children With New-Onset Type 1 Diabetes
- (2016) Anne M. Pesenacker et al. DIABETES
- Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication
- (2016) Sangeeta Dhawan et al. DIABETES
- β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice
- (2016) Fatima Manzoor et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function
- (2016) Yanbao Xiong et al. JOURNAL OF IMMUNOLOGY
- T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN
- (2016) Anna Nosko et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Singular role for T-BET+CXCR3+regulatory T cells in protection from autoimmune diabetes
- (2016) Tze Guan Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protective role of adenovirus vector-mediated interleukin-10 gene therapy on endogenous islet β-cells in recent-onset type 1 diabetes in NOD mice
- (2016) CHENG LI et al. Experimental and Therapeutic Medicine
- Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
- (2016) John A. Todd et al. PLOS MEDICINE
- Therapeutic Window of Interleukin-2 for Autoimmune Diseases: Figure 1
- (2015) Qizhi Tang DIABETES
- Reversal of New-Onset Type 1 Diabetes With an Agonistic TLR4/MD-2 Monoclonal Antibody
- (2015) Kyle J. Bednar et al. DIABETES
- Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
- (2015) Michelle Rosenzwajg et al. JOURNAL OF AUTOIMMUNITY
- Combination Therapy Using IL-2/IL-2 Monoclonal Antibody Complexes, Rapamycin, and Islet Autoantigen Peptides Increases Regulatory T Cell Frequency and Protects against Spontaneous and Induced Type 1 Diabetes in Nonobese Diabetic Mice
- (2015) J. N. Manirarora et al. JOURNAL OF IMMUNOLOGY
- Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
- (2015) Alexandria Huynh et al. NATURE IMMUNOLOGY
- Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice
- (2015) Mara Kornete et al. PLoS One
- Population dynamics of islet-infiltrating cells in autoimmune diabetes
- (2015) Angela M. Magnuson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-35 administration counteracts established murine type 1 diabetes – possible involvement of regulatory T cells
- (2015) Kailash Singh et al. Scientific Reports
- T-bet Expression by Foxp3+ T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis
- (2015) Rhoanne C. McPherson et al. Frontiers in Immunology
- Extension of the CD4+Foxp3+CD25−/low regulatory T-cell subpopulation in type 1 diabetes mellitus
- (2014) András Zóka et al. AUTOIMMUNITY
- Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets — Results of one year follow-up
- (2014) Natalia Marek-Trzonkowska et al. CLINICAL IMMUNOLOGY
- Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes
- (2014) Michael S. Turner et al. DIABETOLOGIA
- -Cell-Specific IL-2 Therapy Increases Islet Foxp3+Treg and Suppresses Type 1 Diabetes in NOD Mice
- (2013) M. C. Johnson et al. DIABETES
- Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2
- (2013) Jonathan Sitrin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-2R Signaling Is Essential for Functional Maturation of Regulatory T Cells during Thymic Development
- (2013) G. Cheng et al. JOURNAL OF IMMUNOLOGY
- Regulatory T cells in nonlymphoid tissues
- (2013) Dalia Burzyn et al. NATURE IMMUNOLOGY
- Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice
- (2013) Elke Gülden et al. PLoS One
- Excessive Th1 responses due to the absence of TGF- signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis
- (2013) H. Ishigame et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial
- (2013) Agnès Hartemann et al. Lancet Diabetes & Endocrinology
- Dendritic Cell Subsets in Type 1 Diabetes: Friend or Foe?
- (2013) Penelope A. Morel Frontiers in Immunology
- Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model
- (2012) Benjamin K Nti et al. Cellular & Molecular Immunology
- TGF Receptor Signaling Is Essential for Inflammation-Induced but Not -Cell Workload-Induced -Cell Proliferation
- (2012) X. Xiao et al. DIABETES
- Administration of CD4+CD25highCD127- Regulatory T Cells Preserves -Cell Function in Type 1 Diabetes in Children
- (2012) N. Marek-Trzonkowska et al. DIABETES CARE
- Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice
- (2012) Y. Yamada et al. DIABETOLOGIA
- ICOS-Dependent Homeostasis and Function of Foxp3+ Regulatory T Cells in Islets of Nonobese Diabetic Mice
- (2012) M. Kornete et al. JOURNAL OF IMMUNOLOGY
- PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
- (2012) Daniela Cipolletta et al. NATURE
- Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes
- (2011) Sridevi Devaraj et al. CYTOKINE
- Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes
- (2011) Alessandra Ferraro et al. DIABETES
- Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation
- (2011) Ilona Gutcher et al. IMMUNITY
- Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets
- (2011) Joel Montane et al. JOURNAL OF CLINICAL INVESTIGATION
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells
- (2010) Marc Vocanson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulatory T Cells Sequentially Migrate from Inflamed Tissues to Draining Lymph Nodes to Suppress the Alloimmune Response
- (2009) Nan Zhang et al. IMMUNITY
- Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function
- (2009) Huei-Min Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- T-bet-Deficient NOD Mice Are Protected from Diabetes Due to Defects in Both T Cell and Innate Immune System Function
- (2009) J. H. Esensten et al. JOURNAL OF IMMUNOLOGY
- The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
- (2009) Meghan A Koch et al. NATURE IMMUNOLOGY
- Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery
- (2008) Tomoki Ito et al. IMMUNITY
- Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction
- (2008) Qizhi Tang et al. IMMUNITY
- Innate immunity and intestinal microbiota in the development of Type 1 diabetes
- (2008) Li Wen et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now