Novel Modulators of Asthma and Allergy: Exosomes and MicroRNAs

Noncoding RNAs and immune checkpoints-clinical implications as cancer therapeutics

(2017) Maria A. Smolle et al.   FEBS Journal

Exosomes from eosinophils autoregulate and promote eosinophil functions

(2017) José Antonio Cañas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Exosomes and their Application in Biomedical Field: Difficulties and Advantages

(2017) Jafar Rezaie et al.   MOLECULAR NEUROBIOLOGY

The link between long noncoding RNAs and depression

(2017) Xiao Huang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

MicroRNAs in melanoma development and resistance to target therapy

(2017) Luigi Fattore et al.   Oncotarget

Exosomes in immunoregulation of chronic lung diseases

(2016) K. P. Hough et al.   ALLERGY

Neutrophil-Derived Exosomes: A New Mechanism Contributing to Airway Smooth Muscle Remodeling

(2016) Amandine Vargas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The role of miRNAs in cardiovascular disease risk factors

(2016) Joy N. Jones Buie et al.   ATHEROSCLEROSIS

Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

(2016) Sergio Portal-Núñez et al.   BIOCHEMICAL PHARMACOLOGY

The role of microRNAs in colorectal cancer

(2016) Ali Mohammadi et al.   BIOMEDICINE & PHARMACOTHERAPY

Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders

(2016) Gilda Varricchi et al.   Current Opinion in Allergy and Clinical Immunology

Regulation of CBL and ESR1 expression by microRNA-22-3p, 513a-5p and 625-5p may impact the pathogenesis of dust mite-induced pediatric asthma

(2016) Xiaoyan Dong et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Asthma inflammatory phenotypes show differential microRNA expression in sputum

(2016) Tania Maes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma

(2016) Ronaldo P. Panganiban et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNAs in glaucoma and neurodegenerative diseases

(2016) Milena Molasy et al.   JOURNAL OF HUMAN GENETICS

ExoCarta: A Web-Based Compendium of Exosomal Cargo

(2016) Shivakumar Keerthikumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation

(2016) Cecilia Lässer et al.   Journal of Translational Medicine

MicroRNA–21 as a novel biomarker in diagnosis and response to therapy in asthmatic children

(2016) Rabab M. Elbehidy et al.   MOLECULAR IMMUNOLOGY

MiR-3162-3p Is a Novel MicroRNA That Exacerbates Asthma by Regulating β-Catenin

(2016) Chao Fang et al.   PLoS One

MicroRNAs, HIV and HCV: a complex relation towards pathology

(2016) Diogo Piedade et al.   REVIEWS IN MEDICAL VIROLOGY

The emerging role of microRNAs in hypoxia-induced pulmonary hypertension

(2016) Vahid Mohsenin   Sleep and Breathing

Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: novel perspectives based on review of the literature

(2016) Mao-Jie Wang et al.   Oncotarget

Molecular Background of miRNA Role in Asthma and COPD: An Updated Insight

(2016) Izabela Szymczak et al.   Biomed Research International

miR-196, an Emerging Cancer Biomarker for Digestive Tract Cancers

(2016) Ya-Ching Lu et al.   Journal of Cancer

Dendritic cell-derived exosomes carry the major cat allergen Fel d 1 and induce an allergic immune response

(2015) H. Vallhov et al.   ALLERGY

Exosome secretion by eosinophils: A possible role in asthma pathogenesis

(2015) Carla Mazzeo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Physical characterization and profiling of airway epithelial derived exosomes using light scattering

(2015) Mehmet Kesimer et al.   METHODS

Mast cells, basophils and B cell connection network

(2015) Sonia Merluzzi et al.   MOLECULAR IMMUNOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity

(2015) Maximilian W. Plank et al.   PLoS One

MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle

(2014) Brian S. Comer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intercellular Communication by Extracellular Vesicles and Their MicroRNAs in Asthma

(2014) Yu Fujita et al.   CLINICAL THERAPEUTICS

MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway

(2014) Ruoxi Hu et al.   FASEB JOURNAL

Altered MicroRNA Expression of Nasal Mucosa in Long-Term Asthma and Allergic Rhinitis

(2014) Hille Suojalehto et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Exosomes from Bronchoalveolar Fluid of Tolerized Mice Prevent Allergic Reaction

(2014) N. Prado et al.   JOURNAL OF IMMUNOLOGY

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production

(2014) Laura J Simpson et al.   NATURE IMMUNOLOGY

A MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells

(2014) Rocio T. Martinez-Nunez et al.   PLoS One

Profiling of Serum and Urinary MicroRNAs in Children with Atopic Dermatitis

(2014) Yani Lv et al.   PLoS One

Airway Smooth Muscle Hyperproliferation is Regulated by microRNA-221 in Severe Asthma

(2013) Mark M Perry et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

(2013) Michel Record et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Exosome-enclosed microRNAs in exhaled breath hold potential for biomarker discovery in patients with pulmonary diseases

(2013) Anirban Sinha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

(2013) Bettina Levänen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lower levels of hsa-mir-15a, which decreases VEGFA, in the CD4+ T cells of pediatric patients with asthma

(2013) Taiji Nakano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proinflammatory role of epithelial cell–derived exosomes in allergic airway inflammation

(2013) Ankur Kulshreshtha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults

(2013) Mark Pinkerton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

(2013) Anatoliy I. Masyuk et al.   JOURNAL OF HEPATOLOGY

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNA profiles in nasal mucosa of patients with allergic and nonallergic rhinitis and asthma

(2013) Hille Suojalehto et al.   International Forum of Allergy & Rhinology

Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma

(2012) P. Torregrosa Paredes et al.   ALLERGY

Untangling asthma phenotypes and endotypes

(2012) I. Agache et al.   ALLERGY

Airway Epithelial miRNA Expression Is Altered in Asthma

(2012) Owen D. Solberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Distinct MicroRNA Expression in Human Airway Cells of Asthmatic Donors Identifies a Novel Asthma-Associated Gene

(2012) Melanie J. Jardim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Extracellular vesicles - vehicles that spread cancer genes

(2012) Janusz Rak et al.   BIOESSAYS

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

(2012) N. Ismail et al.   BLOOD

HomoTarget: A new algorithm for prediction of microRNA targets in Homo sapiens

(2012) Hamed Ahmadi et al.   GENOMICS

Inhibition of miRNA-221 Suppresses the Airway Inflammation in Asthma

(2012) Hou-bing Qin et al.   INFLAMMATION

Secreted Factors from Human Mast Cells Trigger Inflammatory Cytokine Production by Human Airway Smooth Muscle Cells

(2012) Y.C. Xia et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Tissue factor–bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo

(2012) Jin-Ah Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

One Decade of Development and Evolution of MicroRNA Target Prediction Algorithms

(2012) Paula H. Reyes∼Herrera et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi)

(2011) Qiuwei Pan et al.   GUT

Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation

(2011) Manish Kumar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma

(2011) Eleni Tsitsiou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

MicroRNA history: Discovery, recent applications, and next frontiers

(2011) Maria I. Almeida et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target

(2011) Adam Collison et al.   BMC Pulmonary Medicine

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

(2010) Sonja I Buschow et al.   IMMUNOLOGY AND CELL BIOLOGY

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

(2010) Julia Esser et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgE, mast cells, basophils, and eosinophils

(2010) Kelly D. Stone et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proinflammatory Role forlet-7MicroRNAS in Experimental Asthma

(2010) Sumanth Polikepahad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

(2009) Mehmet Kesimer et al.   FASEB JOURNAL

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy

(2009) Andrew E. Williams et al.   PLoS One

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

(2009) J. Mattes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

(2008) Charles H. Lawrie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Eosinophils: Biological Properties and Role in Health and Disease

(2008) SIMON P. HOGAN et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Serum-derived exosomes from antigen-fed mice prevent allergic sensitization in a model of allergic asthma

(2008) Nina Almqvist et al.   IMMUNOLOGY

Sequence Relationships among C. elegans, D. melanogaster and Human microRNAs Highlight the Extensive Conservation of microRNAs in Biology

(2008) Carolina Ibáñez-Ventoso et al.   PLoS One

Dendritic Cells Release HLA-B-Associated Transcript-3 Positive Exosomes to Regulate Natural Killer Function

(2008) Venkateswara Rao Simhadri et al.   PLoS One