Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

MicroRNA-29b mediates altered innate immune development in acute leukemia

(2016) Bethany L. Mundy-Bosse et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

(2016) Rizwan Romee et al.   Science Translational Medicine

Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells

(2016) Nicolas Dulphy et al.   Frontiers in Immunology

Natural killer cell immunosenescence in acute myeloid leukaemia patients: new targets for immunotherapeutic strategies?

(2015) Beatriz Sanchez-Correa et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion

(2015) Zena Khaznadar et al.   JOURNAL OF IMMUNOLOGY

Acute Myeloid Leukemia

(2015) Hartmut Döhner et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1hiTIM-3+ T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation

(2015) Y Kong et al.   Blood Cancer Journal

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Increased NK Cell Maturation in Patients with Acute Myeloid Leukemia

(2015) Anne-Sophie Chretien et al.   Frontiers in Immunology

Targeting the Innate Immune System as Immunotherapy for Acute Myeloid Leukemia

(2015) Emily Curran et al.   Frontiers in Oncology

New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape

(2014) Deepak Mittal et al.   CURRENT OPINION IN IMMUNOLOGY

Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

(2014) Robert K Hills et al.   LANCET ONCOLOGY

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

(2013) F. Mussai et al.   BLOOD

Interaction between natural killer cells and regulatory T cells: perspectives for immunotherapy

(2013) Isabela Pedroza-Pacheco et al.   Cellular & Molecular Immunology

CD40 ligation reverses T cell tolerance in acute myeloid leukemia

(2013) Long Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

At the Bench: Preclinical rationale for exploiting NK cells and γδ T lymphocytes for the treatment of high-risk leukemias

(2013) Håkan Norell et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Location and cellular stages of natural killer cell development

(2013) Jianhua Yu et al.   TRENDS IN IMMUNOLOGY

Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease

(2013) Carolyn M. Nielsen et al.   Frontiers in Immunology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients

(2011) Beatriz Sanchez-Correa et al.   IMMUNOLOGY AND CELL BIOLOGY

CD56brightCD16+ NK Cells: A Functional Intermediate Stage of NK Cell Differentiation

(2011) V. Beziat et al.   JOURNAL OF IMMUNOLOGY

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

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Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

(2010) N. K. Bjorkstrom et al.   BLOOD

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset

(2010) S. Lopez-Verges et al.   BLOOD

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

(2009) Q. Zhou et al.   BLOOD

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts

(2009) R. Le Dieu et al.   BLOOD

PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model

(2009) L. Zhang et al.   BLOOD

Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia

(2009) M. J. Szczepanski et al.   CLINICAL CANCER RESEARCH

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

(2008) A. Curti et al.   BLOOD