Molecular mechanism of polymer-assisting supersaturation of poorly water-soluble loratadine based on experimental observations and molecular dynamic simulations

Crystallizing Micronized Particles of a Poorly Water-Soluble Active Pharmaceutical Ingredient: Nucleation Enhancement by Polymeric Additives

(2016) Sendhil K. Poornachary et al.   CRYSTAL GROWTH & DESIGN

Supersaturation Potential of Salt, Co-Crystal, and Amorphous Forms of a Model Weak Base

(2016) Luis Almeida e Sousa et al.   CRYSTAL GROWTH & DESIGN

Solvent-shift strategy to identify suitable polymers to inhibit humidity-induced solid-state crystallization of lacidipine amorphous solid dispersions

(2016) Mengchi Sun et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Probing the role of chemical enhancers in facilitating drug release from patches: Mechanistic insights based on FT-IR spectroscopy, molecular modeling and thermal analysis

(2016) Wenting Song et al.   JOURNAL OF CONTROLLED RELEASE

A silica-supported solid dispersion of bifendate using supercritical carbon dioxide method with enhanced dissolution rate and oral bioavailability

(2015) Cuifang Cai et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Probing the mechanisms of drug release from amorphous solid dispersions in medium-soluble and medium-insoluble carriers

(2015) Dajun D. Sun et al.   JOURNAL OF CONTROLLED RELEASE

Drug–Polymer–Water Interaction and Its Implication for the Dissolution Performance of Amorphous Solid Dispersions

(2015) Yuejie Chen et al.   MOLECULAR PHARMACEUTICS

Computer-Assisted Drug Formulation Design: Novel Approach in Drug Delivery

(2015) Abdelkader A. Metwally et al.   MOLECULAR PHARMACEUTICS

Prediction of oral absorption of cinnarizine – A highly supersaturating poorly soluble weak base with borderline permeability

(2014) Mark Berlin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Dissolution evaluationin vitroand bioavailabilityin vivoof self-microemulsifying drug delivery systems for pH-sensitive drug loratadine

(2014) Haiyan Li et al.   JOURNAL OF MICROENCAPSULATION

Excipient-Assisted Vinpocetine Nanoparticles: Experiments and Molecular Dynamic Simulations

(2014) Cai-Xia Li et al.   MOLECULAR PHARMACEUTICS

Impact of Polymers on the Crystallization and Phase Transition Kinetics of Amorphous Nifedipine during Dissolution in Aqueous Media

(2014) Shweta A. Raina et al.   MOLECULAR PHARMACEUTICS

Assessing the Efficiency of Polymeric Excipients by Atomistic Molecular Dynamics Simulations

(2014) Prateek K. Jha et al.   MOLECULAR PHARMACEUTICS

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

(2013) Romelia Salomon-Ferrer et al.   Journal of Chemical Theory and Computation

Studies of Bicalutamide–Excipients Interaction by Combination of Molecular Docking and Molecular Dynamics Simulation

(2013) Caixia Li et al.   MOLECULAR PHARMACEUTICS

Investigating the molecular structures of solid dispersions by the simulated annealing method

(2012) Defang Ouyang   CHEMICAL PHYSICS LETTERS

Effect of Additives on Crystal Growth and Nucleation of Amorphous Flutamide

(2012) Niraj S. Trasi et al.   CRYSTAL GROWTH & DESIGN

Preparation and characterization of fusion processed solid dispersions containing a viscous thermally labile polymeric carrier

(2012) Justin R. Hughey et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solvent shift method for anti-precipitant screening of poorly soluble drugs using biorelevant medium and dimethyl sulfoxide

(2011) Taro Yamashita et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of relative humidity on the interaction between different aryl propionic acid derivatives and poly(vinylpyrrolydone) K30: Evaluation of the effect on drug bioavailability

(2010) Ledjan Malaj et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

PACKMOL: A package for building initial configurations for molecular dynamics simulations

(2009) L. Martínez et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Acid–base equilibria and solubility of loratadine and desloratadine in water and micellar media

(2008) Gordana Popović et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS