Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply
Authors
Keywords
-
Journal
Clinical and Translational Gastroenterology
Volume 8, Issue 6, Pages e98
Publisher
Springer Nature
Online
2017-06-16
DOI
10.1038/ctg.2017.28
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma
- (2016) Yves-Paul Vandewynckel et al. BMC CANCER
- Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26
- (2016) David Kung-Chun Chiu et al. HEPATOLOGY
- Phase III randomized study of sorafenib plus doxorubicin versus sorafenib in patients with advanced hepatocellular carcinoma (HCC): CALGB 80802 (Alliance).
- (2016) Ghassan K. Abou-Alfa et al. JOURNAL OF CLINICAL ONCOLOGY
- Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: The SPACE trial
- (2016) Riccardo Lencioni et al. JOURNAL OF HEPATOLOGY
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
- (2016) Yunlong Yang et al. Nature Communications
- A randomized study of KRAS-guided maintenance therapy with bevacizumab, erlotinib or metronomic capecitabine after first-line induction treatment of metastatic colorectal cancer: the Nordic ACT2 trial
- (2015) H. Hagman et al. ANNALS OF ONCOLOGY
- Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210
- (2015) Muhammad Zaeem Noman et al. CANCER RESEARCH
- CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice
- (2015) Yunching Chen et al. HEPATOLOGY
- Hypoxia after transarterial chemoembolization may trigger a progenitor cell phenotype in hepatocellular carcinoma
- (2015) Jin-Ping Lai et al. HISTOPATHOLOGY
- SEARCH: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Sorafenib Plus Erlotinib in Patients With Advanced Hepatocellular Carcinoma
- (2015) Andrew X. Zhu et al. JOURNAL OF CLINICAL ONCOLOGY
- Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trial
- (2015) Andrew X Zhu et al. LANCET ONCOLOGY
- Hepatocellular Carcinoma: A Phase II Randomized Controlled Double-Blind Trial of Transarterial Chemoembolization in Combination with Biweekly Intravenous Administration of Bevacizumab or a Placebo
- (2015) Matthias Pinter et al. RADIOLOGY
- Vascular Normalization Induced by Sinomenine Hydrochloride Results in Suppressed Mammary Tumor Growth and Metastasis
- (2015) Huimin Zhang et al. Scientific Reports
- Immune checkpoint blockade in hepatocellular carcinoma: Current progress and future directions
- (2014) Tai Hato et al. HEPATOLOGY
- Influence of preoperative transcatheter arterial chemoembolization on gene expression in the HIF-1α pathway in patients with hepatocellular carcinoma
- (2014) Weiguang Xu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions
- (2014) Garrick K. Wilson et al. JOURNAL OF HEPATOLOGY
- Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27
- (2013) J. A. Young et al. BLOOD
- A randomised phase II/III trial of 3-weekly cisplatin-based sequential transarterial chemoembolisation vs embolisation alone for hepatocellular carcinoma
- (2013) T Meyer et al. BRITISH JOURNAL OF CANCER
- Vascular Normalization as an Emerging Strategy to Enhance Cancer Immunotherapy
- (2013) Y. Huang et al. CANCER RESEARCH
- Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling
- (2013) Qi Zhang et al. CARCINOGENESIS
- A Phase II and Biomarker Study of Ramucirumab, a Human Monoclonal Antibody Targeting the VEGF Receptor-2, as First-Line Monotherapy in Patients with Advanced Hepatocellular Cancer
- (2013) A. X. Zhu et al. CLINICAL CANCER RESEARCH
- Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study
- (2013) A. X. Zhu et al. CLINICAL CANCER RESEARCH
- Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial
- (2013) Ann-Lii Cheng et al. JOURNAL OF CLINICAL ONCOLOGY
- Ectopic Blood Supply of Hepatocellular Carcinoma as Depicted by Angiography with Computed Tomography: Associations with Morphological Features and Therapeutic History
- (2013) Guang-wen Chen et al. PLoS One
- Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization
- (2012) Wen-Quan Wang et al. Journal of Hematology & Oncology
- Claudin-1 induces epithelial–mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells
- (2012) Y Suh et al. ONCOGENE
- Efficacy of Bevacizumab plus Erlotinib for Advanced Hepatocellular Carcinoma and Predictors of Outcome: Final Results of a Phase II Trial
- (2012) A.O. Kaseb et al. ONCOLOGY
- Cediranib (AZD2171) in Patients With Advanced Hepatocellular Carcinoma
- (2011) Steven Robert Alberts et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Phase 2 trial of bevacizumab, capecitabine, and oxaliplatin in treatment of advanced hepatocellular carcinoma
- (2011) Weijing Sun et al. CANCER
- Management of hepatocellular carcinoma: An update
- (2011) Jordi Bruix et al. HEPATOLOGY
- Phase II Study of Concomitant Thalidomide During Radiotherapy for Hepatocellular Carcinoma
- (2011) Hui-Ju Ch’ang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Role of vascular endothelial growth factor in angiodysplasia: An interventional study with thalidomide
- (2011) Honghong Tan et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Chemoembolization for intermediate HCC: Is there proof of survival benefit?
- (2011) Alejandro Forner et al. JOURNAL OF HEPATOLOGY
- Radioembolization for hepatocellular carcinoma
- (2011) Bruno Sangro et al. JOURNAL OF HEPATOLOGY
- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
- (2011) Andrea Facciabene et al. NATURE
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Normalization of the Vasculature for Treatment of Cancer and Other Diseases
- (2011) Shom Goel et al. PHYSIOLOGICAL REVIEWS
- Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease
- (2010) Sara Van de Veire et al. CELL
- Doxorubicin Plus Sorafenib vs Doxorubicin Alone in Patients With Advanced Hepatocellular Carcinoma
- (2010) Ghassan K. Abou-Alfa et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre-Clinical Models
- (2010) DAI FUKUMURA et al. MICROCIRCULATION
- Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma
- (2010) Zuo-Lin Xiang et al. MOLECULAR BIOLOGY REPORTS
- Prospective Randomized Comparison of Chemoembolization with Doxorubicin-Eluting Beads and Bland Embolization with BeadBlock for Hepatocellular Carcinoma
- (2009) Katerina Malagari et al. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
- An Akt/Hypoxia-Inducible Factor-1 /Platelet-Derived Growth Factor-BB Autocrine Loop Mediates Hypoxia-Induced Chemoresistance in Liver Cancer Cells and Tumorigenic Hepatic Progenitor Cells
- (2009) C. K. Lau et al. CLINICAL CANCER RESEARCH
- Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study
- (2009) Andrew X. Zhu et al. JOURNAL OF CLINICAL ONCOLOGY
- Anticancer strategies involving the vasculature
- (2009) Victoria L. Heath et al. Nature Reviews Clinical Oncology
- Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy
- (2009) George J. Cerniglia et al. PLoS One
- Early Hepatocellular Carcinoma: Pathology, Imaging, and Therapy
- (2008) Tadatoshi Takayama et al. ANNALS OF SURGICAL ONCOLOGY
- 398 POSTER Phase I, pharmacokinetic (PK), dose-escalation study of EZN-2968, a novel hypoxia-inducible factor-1 alpha (HIF-1a) antagonist, administered weekly in patients (pts) with solid tumours
- (2008) N. Lewis et al. EJC SUPPLEMENTS
- Phase II Trial Evaluating the Clinical and Biologic Effects of Bevacizumab in Unresectable Hepatocellular Carcinoma
- (2008) Abby B. Siegel et al. JOURNAL OF CLINICAL ONCOLOGY
- Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. JNCI-Journal of the National Cancer Institute
- A RNA antagonist of hypoxia-inducible factor-1 , EZN-2968, inhibits tumor cell growth
- (2008) L. M. Greenberger et al. MOLECULAR CANCER THERAPEUTICS
- Vascular normalization in Rgs5-deficient tumours promotes immune destruction
- (2008) Juliana Hamzah et al. NATURE
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now