An update on prucalopride in the treatment of chronic constipation

Effect of prucalopride on intestinal gas tolerance in patients with functional bowel disorders and constipation

(2017) Carolina Malagelada et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Randomised clinical trial: prucalopride, a colonic pro-motility agent, reduces the duration of post-operative ileus after elective gastrointestinal surgery

(2016) J. Gong et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prucalopride exerts neuroprotection in human enteric neurons

(2016) Francesca Bianco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Phase I Study to Investigate the Absorption, Pharmacokinetics, and Excretion of [14C]Prucalopride After a Single Oral Dose in Healthy Volunteers

(2016) Stephen Flach et al.   CLINICAL THERAPEUTICS

Efficacy and Safety of Prucalopride in Chronic Constipation: An Integrated Analysis of Six Randomized, Controlled Clinical Trials

(2016) Michael Camilleri et al.   DIGESTIVE DISEASES AND SCIENCES

Activation of islet 5-HT 4 receptor regulates glycemic control through promoting insulin secretion

(2016) Hui Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Bowel Disorders

(2016) Brian E. Lacy et al.   GASTROENTEROLOGY

Lubiprostone Is Effective in the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome

(2016) Fan Li et al.   MAYO CLINIC PROCEEDINGS

Prucalopride induces high-amplitude propagating contractions in the colon of patients with chronic constipation: a randomized study

(2016) P. B. Miner et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Epidemiology and Burden of Chronic Constipation

(2016) Maria Ines Pinto Sanchez et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety and Tolerability of Prucalopride in Men With Chronic Constipation

(2015) Yan Yiannakou et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The 5-HT4Agonist Prucalopride Stimulates L-DOPA-Induced Dopamine Release in Restricted Brain Regions of the Hemiparkinsonian RatIn Vivo

(2015) Sylvia Navailles et al.   CNS Neuroscience & Therapeutics

Long-term outcome of prucalopride for chronic constipation: a single-centre study

(2015) P. K. Dhruva Rao et al.   Colorectal Disease

Advancing treatment options for chronic idiopathic constipation

(2015) Eamonn M. M. Quigley et al.   EXPERT OPINION ON PHARMACOTHERAPY

Factors Predictive of Treatment-Emergent Adverse Events of Prucalopride: An Integrated Analysis of Four Randomized, Double-Blind, Placebo-Controlled Trials

(2015) Somchai Leelakusolvong et al.   Gut and Liver

Role of Prucalopride in Treatment of Chronic Constipation and Recurrent Functional Obstruction in a Patient With Steinert Myotonic Dystrophy

(2015) Mariano Cesare Giglio et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of long-term treatment with prucalopride

(2015) H. Piessevaux et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Association between health-related quality of life and symptoms in patients with chronic constipation: an integrated analysis of three phase 3 trials of prucalopride

(2015) J. Tack et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Cost-effectiveness of prucalopride in the treatment of chronic constipation in the Netherlands

(2015) Mark J. C. Nuijten et al.   Frontiers in Pharmacology

American College of Gastroenterology Monograph on the Management of Irritable Bowel Syndrome and Chronic Idiopathic Constipation

(2014) Alexander C Ford et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Linaclotide: A novel agent for chronic constipation and irritable bowel syndrome

(2014) B. L. Love et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Prucalopride Is No More Effective Than Placebo for Children With Functional Constipation

(2014) Suzanne M. Mugie et al.   GASTROENTEROLOGY

Pharmacoeconomic study of chronic constipation in a secondary care centre

(2014) C. Walsh et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Prucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjects

(2014) B. F. Kessing et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Acute refractory intestinal pseudo-obstruction in MELAS: Efficacy of prucalopride

(2014) G. Primiano et al.   NEUROLOGY

Prucalopride-associated acute tubular necrosis

(2014) Vithika Sivabalasundaram   World Journal of Clinical Cases

Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation

(2013) A. Shin et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Randomised clinical trial: macrogol/PEG 3350+electrolytes versus prucalopride in the treatment of chronic constipation - a comparison in a controlled environment

(2013) R. Cinca et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Neurological and psychiatric adverse events with prucalopride: case report and possible mechanisms

(2013) C. Carnovale et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Oral Prucalopride in Children With Functional Constipation

(2013) Harland S. Winter et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Comorbidities in Patients With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: A Review of the Literature From the Past Decade

(2013) Dave Nellesen et al.   POSTGRADUATE MEDICINE

The association between prucalopride efficacy and constipation type

(2013) A. M. Jadav et al.   Techniques in Coloproctology

Effect of Prucalopride on the Pharmacokinetics of Oral Contraceptives in Healthy Women

(2013) Vera Van de Velde et al.   Drugs in research & development

Efficacy and safety of oral prucalopride in women with chronic constipation in whom laxatives have failed: an integrated analysis

(2013) Jan Tack et al.   United European Gastroenterology Journal

Systematic review: cardiovascular safety profile of 5-HT4 agonists developed for gastrointestinal disorders

(2012) J. Tack et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prucalopride: evaluation of the pharmacokinetics, pharmacodynamics, efficacy and safety in the treatment of chronic constipation

(2012) Jan Tack et al.   Expert Opinion on Drug Metabolism & Toxicology

Prucalopride in the treatment of chronic constipation in patients from the Asia-Pacific region: a randomized, double-blind, placebo-controlled study

(2012) M. Ke et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction - a double-blind, placebo-controlled, cross-over, multiple n = 1 study

(2011) A. V. Emmanuel et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Opioid-Induced Constipation: Challenges and Therapeutic Opportunities

(2011) Michael Camilleri   AMERICAN JOURNAL OF GASTROENTEROLOGY

Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo- and positive-controlled thorough QT study

(2011) Boaz Mendzelevski et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Impact of Chronic Constipation on Health-Related Quality of Life, Work Productivity, and Healthcare Resource Use: An Analysis of the National Health and Wellness Survey

(2011) Shawn X. Sun et al.   DIGESTIVE DISEASES AND SCIENCES

Cisapride: What can we learn from the rise and fall of a prokinetic?

(2011) Eamonn MM QUIGLEY   Journal of Digestive Diseases

The inability of tegaserod to affect platelet aggregation and coronary artery tone at supratherapeutic concentrations

(2011) Deborah L. Higgins et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The facilitating effect of prucalopride on cholinergic neurotransmission in pig gastric circular muscle is regulated by phosphodiesterase 4

(2011) Evelien Priem et al.   NEUROPHARMACOLOGY

Clinical trial: the efficacy of open-label prucalopride treatment in patients with chronic constipation - follow-up of patients from the pivotal studies

(2010) M. Camilleri et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation

(2010) Cornelius E. J. Sloots et al.   DIGESTIVE DISEASES AND SCIENCES

Tegaserod and the Risk of Cardiovascular Ischemic Events: An Observational Cohort Study

(2010) Jeanne Loughlin et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

5-HT4 receptor agonists: similar but not the same

(2010) J. H. De Maeyer et al.   NEUROGASTROENTEROLOGY AND MOTILITY

A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation

(2010) S. Müller-lissner et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study

(2009) m. camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Psychometric performance and clinical meaningfulness of the Patient Assessment of Constipation – Quality of Life questionnaire in prucalopride (RESOLOR®) trials for chronic constipation

(2009) d. dubois et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation - a 12-week, randomized, double-blind, placebo-controlled study

(2008) E. M. M. QUIGLEY et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives

(2008) J Tack et al.   GUT

A Review of the Literature on Gender and Age Differences in the Prevalence and Characteristics of Constipation in North America

(2008) G. Lindsay McCrea et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation

(2008) Michael Camilleri et al.   NEW ENGLAND JOURNAL OF MEDICINE