Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes

Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA–DNA hybrids

(2016) Karan J. Abraham et al.   NUCLEIC ACIDS RESEARCH

TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions

(2016) Rekha Rai et al.   Nature Communications

Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 inSaccharomyces cerevisiae

(2015) Hannah Kaizer et al.   GENETICS

LINE-1 in cancer: multifaceted functions and potential clinical implications

(2015) Lu Xiao-Jie et al.   GENETICS IN MEDICINE

Atrans-Dominant Form of Gag Restricts Ty1 Retrotransposition and Mediates Copy Number Control

(2015) Agniva Saha et al.   JOURNAL OF VIROLOGY

miR-128 represses L1 retrotransposition by binding directly to L1 RNA

(2015) Matthias Hamdorf et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ty1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions

(2015) Yuri Nishida et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analyses of LINE–LINE-mediated nonallelic homologous recombination

(2015) Michał Startek et al.   NUCLEIC ACIDS RESEARCH

An RNA polymerase III subunit determines sites of retrotransposon integration

(2015) A. Bridier-Nahmias et al.   SCIENCE

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase

(2015) Aaron L. Moye et al.   Nature Communications

miR-128 represses L1 retrotransposition by binding directly to L1 RNA

(2015) Matthias Hamdorf et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ty1 Retrotransposon Restriction Factor p22 Targets Gag

(2015) Jessica M. Tucker et al.   PLoS Genetics

The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae

(2015) Evan P Hass et al.   eLife

Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 inSaccharomyces cerevisiae

(2015) Hannah Kaizer et al.   GENETICS

R-loops highlight the nucleus in ALS

(2015) Jayesh S Salvi et al.   Nucleus

R-loops highlight the nucleus in ALS

(2015) Jayesh S Salvi et al.   Nucleus

Guanine quadruplexes are formed by specific regions of human transposable elements

(2014) Matej Lexa et al.   BMC GENOMICS

Roles for Pbp1 and Caloric Restriction in Genome and Lifespan Maintenance via Suppression of RNA-DNA Hybrids

(2014) Jayesh S. Salvi et al.   DEVELOPMENTAL CELL

Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability

(2014) Guliang Wang et al.   DNA REPAIR

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells

(2014) D. Pezic et al.   GENES & DEVELOPMENT

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

(2014) E. Helman et al.   GENOME RESEARCH

Telomeropathies: An emerging spectrum disorder

(2014) Brody Holohan et al.   JOURNAL OF CELL BIOLOGY

Ribosomal RNA gene repeats, their stability and cellular senescence

(2014) Takehiko KOBAYASHI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase

(2014) Tai-Yuan Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

(2014) S. Ray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells

(2014) Rajika Arora et al.   Nature Communications

Genome-Wide Profiling of Yeast DNA:RNA Hybrid Prone Sites with DRIP-Chip

(2014) Yujia A. Chan et al.   PLoS Genetics

Genome-Wide Distribution of RNA-DNA Hybrids Identifies RNase H Targets in tRNA Genes, Retrotransposons and Mitochondria

(2014) Aziz El Hage et al.   PLoS Genetics

Identification of human TERT elements necessary for telomerase recruitment to telomeres

(2014) Jens C Schmidt et al.   eLife

Death by transposition - the enemy within?

(2013) John M. Sedivy et al.   BIOESSAYS

The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening

(2013) Verena Pfeiffer et al.   EMBO JOURNAL

R Loops Are Linked to Histone H3 S10 Phosphorylation and Chromatin Condensation

(2013) Maikel Castellano-Pozo et al.   MOLECULAR CELL

Migrating bubble during break-induced replication drives conservative DNA synthesis

(2013) Natalie Saini et al.   NATURE

Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

(2013) Bettina Balk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quadruplex-forming sequences occupy discrete regions inside plant LTR retrotransposons

(2013) M. Lexa et al.   NUCLEIC ACIDS RESEARCH

Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1

(2012) Jayesh S. Salvi et al.   AGING CELL

Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA

(2012) Carolyn M. George et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Active human retrotransposons: variation and disease

(2012) Dustin C Hancks et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations

(2012) C. Robberecht et al.   GENOME RESEARCH

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

(2012) Jayakrishnan Nandakumar et al.   NATURE

The telomere syndromes

(2012) Mary Armanios et al.   NATURE REVIEWS GENETICS

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders

(2012) Wanhe Li et al.   PLoS One

The Smc complexes in DNA damage response

(2012) Nan Wu et al.   Cell and Bioscience

New clues to understand the role of THO and other functionally related factors in mRNP biogenesis

(2011) Rosa Luna et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast

(2011) Takehiko Kobayashi   CELLULAR AND MOLECULAR LIFE SCIENCES

Telomerase regulation

(2011) Catherine Cifuentes-Rojas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Maintaining the end: Roles of telomere proteins in end-protection, telomere replication and length regulation

(2011) Jason A. Stewart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae

(2011) Jasmine S Smith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro

(2011) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

(2011) A. P. Jason de Koning et al.   PLoS Genetics

DNA Transposons: Nature and Applications in Genomics

(2010) Martin Munoz-Lopez et al.   CURRENT GENOMICS

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

(2010) A. El Hage et al.   GENES & DEVELOPMENT

TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres In Vivo

(2010) E. Abreu et al.   MOLECULAR AND CELLULAR BIOLOGY

The nuclear envelope in genome organization, expression and stability

(2010) Karim Mekhail et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Abundance of Ribosomal RNA Gene Copies Maintains Genome Integrity

(2010) S. Ide et al.   SCIENCE

Non-B DNA structure-induced genetic instability and evolution

(2009) Junhua Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of rDNA stability by sumoylation

(2009) Nadine Eckert-Boulet et al.   DNA REPAIR

Rrm3 Protects the Saccharomyces cerevisiae Genome From Instability at Nascent Sites of Retrotransposition

(2009) R. Stamenova et al.   GENETICS

Posttranslational interference of Ty1 retrotransposition by antisense RNAs

(2009) E. Matsuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple pathways inhibit NHEJ at telomeres

(2008) S. Marcand et al.   GENES & DEVELOPMENT

A cryptic unstable transcript mediates transcriptional trans-silencing of the Ty1 retrotransposon in S. cerevisiae

(2008) J. Berretta et al.   GENES & DEVELOPMENT

Comparative Analyses of Human Single- and Multilocus Tandem Repeats

(2008) D. Ames et al.   GENETICS

Role for perinuclear chromosome tethering in maintenance of genome stability

(2008) Karim Mekhail et al.   NATURE

Overproduction of non-translatable mRNA silences. The transcription ofTy1 retrotransposons inS. cerevisiae via functional inactivation of the nuclear cap-binding complex and subsequent hyperstimulation of the TORC1 pathway

(2008) Xiaofeng Wu et al.   YEAST

An essential role of Tap42-associated PP2A and 2A-like phosphatases inTy1transcriptional silencing ofS. cerevisiae

(2008) Yi Wei Jiang   YEAST