Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

(2016) Cláudia Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Association of Methotrexate with Native and PEGylated PAMAM-G4 Dendrimers: Effect of the PEGylation Degree on the Drug-Loading Capacity and Preferential Binding Sites

(2016) Luis F. Barraza et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Mechanism of PAMAM Dendrimers Internalization in Hippocampal Neurons

(2016) Felipe Vidal et al.   MOLECULAR PHARMACEUTICS

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

(2016) Alan Enciso et al.   MOLECULES

Dendrimers in Medicine: Therapeutic Concepts and Pharmaceutical Challenges

(2015) Lin-ping Wu et al.   BIOCONJUGATE CHEMISTRY

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

(2015) Andreas Wicki et al.   JOURNAL OF CONTROLLED RELEASE

PAMAM dendrimer with 4-carbomethoxypyrrolidone—In vitro assessment of neurotoxicity

(2015) Anna Janaszewska et al.   Nanomedicine-Nanotechnology Biology and Medicine

A holistic approach to targeting disease with polymeric nanoparticles

(2015) Christopher J. Cheng et al.   NATURE REVIEWS DRUG DISCOVERY

Dendrimer nanocarriers drug action: perspective for neuronal pharmacology

(2015) Leonardo Guzman et al.   Neural Regeneration Research

Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity

(2015) Christian Peters et al.   NEUROBIOLOGY OF AGING

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

(2014) Shaofei Wang et al.   BIOMATERIALS

Folate-functionalized dendrimers for targeting Chlamydia-infected tissues in a mouse model of reactive arthritis

(2014) Ilyes Benchaala et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications

(2014) R. M. Kannan et al.   JOURNAL OF INTERNAL MEDICINE

Dendrimer Advances for the Central Nervous System Delivery of Therapeutics

(2013) Leyuan Xu et al.   ACS Chemical Neuroscience

Sodium selective ion channel formation in living cell membranes by polyamidoamine dendrimer

(2013) Gabriella Nyitrai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Modified PAMAM dendrimer with 4-carbomethoxypyrrolidone surface groups reveals negligible toxicity against three rodent cell-lines

(2013) Anna Janaszewska et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanotherapeutic approaches for brain cancer management

(2013) Laura Saenz del Burgo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Angiopep-Conjugated Nanoparticles for Targeted Long-Term Gene Therapy of Parkinson’s Disease

(2013) Rongqin Huang et al.   PHARMACEUTICAL RESEARCH

Dendrimer as nanocarrier for drug delivery

(2013) Prashant Kesharwani et al.   PROGRESS IN POLYMER SCIENCE

Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review

(2013) Jiangyu Wu et al.   TheScientificWorldJOURNAL

Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue

(2013) Gabriella Nyitrai et al.   JOURNAL OF NANOBIOTECHNOLOGY

Gene and doxorubicin co-delivery system for targeting therapy of glioma

(2012) Shuhuan Liu et al.   BIOMATERIALS

Targeted therapy for cancer using pH-responsive nanocarrier systems

(2012) Somkamon Manchun et al.   LIFE SCIENCES

Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate the Cellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells

(2012) Susana R. Cerqueira et al.   MACROMOLECULAR BIOSCIENCE

In Vivo Distribution and Toxicity of PAMAM Dendrimers in the Central Nervous System Depend on Their Surface Chemistry

(2012) Lorenzo Albertazzi et al.   MOLECULAR PHARMACEUTICS

Surface modification of PAMAM dendrimer improves its biocompatibility

(2012) Michal Ciolkowski et al.   Nanomedicine-Nanotechnology Biology and Medicine

Polyamidoamine dendrimer nanoparticle cytotoxicity, oxidative stress, caspase activation and inflammatory response: experimental observation and numerical simulation

(2012) Sourav Prasanna Mukherjee et al.   Nanomedicine-Nanotechnology Biology and Medicine

Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model

(2012) S. Kannan et al.   Science Translational Medicine

Barriers to Non-Viral Vector-Mediated Gene Delivery in the Nervous System

(2011) Francisco C. Pérez-Martínez et al.   PHARMACEUTICAL RESEARCH

Dendrimer toxicity: Let's meet the challenge

(2010) Keerti Jain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synaptotoxicity of Alzheimer Beta Amyloid Can Be Explained by Its Membrane Perforating Property

(2010) Fernando J. Sepulveda et al.   PLoS One

The decrease of PAMAM dendrimer-induced cytotoxicity by PEGylation via attenuation of oxidative stress

(2009) Wei Wang et al.   NANOTECHNOLOGY

Application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability

(2008) Narendra K Jain et al.   Expert Opinion on Drug Metabolism & Toxicology

Wide Varieties of Cationic Nanoparticles Induce Defects in Supported Lipid Bilayers

(2008) Pascale R. Leroueil et al.   NANO LETTERS